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991.
Leblanc A Ruud KL Branda ME Tiedje K Boehmer KR Pencille LJ Van Houten H Matthews M Shah ND May CR Yawn BP Montori VM 《BMC health services research》2012,12(1):130-9
ABSTRACT: BACKGROUND: Shared decision making contributes to high quality healthcare by promoting a patientcentered approach. Patient involvement in selecting the components of a diabetes medication program that best match the patient's values and preferences may also enhance medication adherence and improve outcomes. Decision aids are tools designed to involve patients in shared decision making, but their adoption in practice has been limited. In this study, we propose to obtain a preliminary estimate of the impact of patient decision aids vs. usual care on measures of patient involvement in decision making, diabetes care processes, medication adherence, glycemic and cardiovascular risk factor control, and resource utilization. In addition, we propose to identify, describe, and explain factors that promote or inhibit the routine embedding of decision aids in practice. METHODS: We will be conducting a mixed-methods study comprised of a cluster-randomized, practical, multicentered trial enrolling clinicians and their patients (n = 240) with type 2 diabetes from rural and suburban primary care practices (n = 8), with an embedded qualitative study to examine factors that influence the incorporation of decision aids into routine practice. The intervention will consist of the use of a decision aid (Statin Choice and Aspirin Choice, or Diabetes Medication Choice) during the clinical encounter. The qualitative study will include analysis of video recordings of clinical encounters and in-depth, semi-structured interviews with participating patients, clinicians, and clinic support staff, in both trial arms. DISCUSSION: Upon completion of this trial, we will have new knowledge about the effectiveness of diabetes decision aids in these practices. We will also better understand the factors that promote or inhibit the successful implementation and normalization of medication choice decision aids in the care of chronic patients in primary care practices. Trial registration NCT00388050. 相似文献
992.
993.
Harris JK Karamehic-Muratovic A Herbers SH Moreland-Russell S Cheskin R Lindberg KA 《Journal of immigrant and minority health / Center for Minority Public Health》2012,14(3):413-419
More than 60% of Bosnian refugees in the United States may be current smokers. Examining health beliefs can provide insight
into smoking behaviors in this community. Four hundred ninety-nine Bosnians were interviewed about health beliefs and personal
health risks related to smoking. ANOVA was used to compare current, former, and never smokers. General health beliefs were
significantly different by smoking status with medium effect sizes (P < .001; η2 = 0.04–0.06); current smokers were less likely to agree that smokers live shorter lives and that smokers are more likely
to get heart disease. Significant differences with large effect sizes (P < .001; η2 = 0.11–0.29) were found in perception of personal risk of lung cancer and heart disease among current, former, and never
smokers. Current smokers perceived their own health risks as less severe than those of other smokers. High smoking rates and
smokers’ optimism related to health indicate that culturally tailored educational and cessation interventions are needed for
Bosnian refugee communities. 相似文献
994.
Telling stories is essential to the continuous process of creating meaning and to self-understanding. Persons with aphasia are vulnerable to psychosocial problems by their limited ability to talk and interact with others. This single-case study illustrates how a young woman with aphasia and a trained nurse interacted to coconstruct stories within the context of a longitudinal clinical intervention aimed at promoting psychosocial well-being in the first year after a stroke. Data were collected through qualitative interviews and participant observation; they were then analyzed from a hermeneutic-phenomenological perspective. The experience of coconstructing stories made an important contribution to improving the participant's psychological well-being. The shared construction of the participant's story evolved as a cumulative process, and it was facilitated by the establishment of trust in the participant-nurse relationship, the systematic use of worksheets and supported conversations, and a specific focus on psychosocial topics and structural organization. 相似文献
995.
996.
997.
Visscher KL Hutnik CM 《Canadian journal of ophthalmology. Journal canadien d'ophtalmologie》2012,47(1):72-78
Health literacy represents the cognitive and social skills that determine the motivation and ability of individuals to gain access to, understand, and use information in ways that promote and maintain good health.(1) According to the 2003 International Adult Literacy and Life Skills Survey (IALSS), over 12 million (60%) adult Canadians lack the capacity to obtain, understand, and act on health information and services, as well as make appropriate health decisions on their own.(2,3) Of these 12 million Canadians, the elderly are the most health illiterate age group in Canada. What this suggests for Canadian physicians is that to improve the CanMEDS roles of communicator and health advocate,(4) physicians need to recognize health literacy as a modifiable contributor of poor health outcomes and work to remove literacy-related barriers.(5) This is particularly important for ophthalmologists who manage chronic illnesses in elderly patients.(2,6,7) The objective of this review is 2-fold. The first objective is to describe health literacy in Canada and provide a summary on the current state of health literacy research, both generally in medicine and specifically to Ophthalmology. The second objective is to propose a 3-step approach of evidence based techniques for managing low health literate patients in clinic. 相似文献
998.
999.
DE Laurie RK Splan K Green KM Still RL McKown GW Laurie 《Investigative ophthalmology & visual science》2012,53(10):6130-6136
Purpose. Lacritin is a human tear glycoprotein that promotes basal tear protein secretion in cultured rat lacrimal acinar cells and proliferation of subconfluent human corneal epithelial cells. When topically added to rabbit eyes, lacritin promotes basal tearing. Despite these activities on several species, lacritin's presence in nonprimate tears or other tissues has not been explored. Here we probed for lacritin in normal horse tears. Methods. Sequences were collected from the Ensembl genomic alignment of human LACRT gene with high-quality draft horse genome (EquCab2.0) and analyzed. Normal horse tears were collected and assayed by Western blotting, ELISA, and mass spectrometry. Newly generated rabbit antibodies, respectively, against N- and C-terminal regions of human lacritin were employed. Results. Identity was 75% and 45%, respectively, at nucleotide and protein levels. Structural features were conserved, including a C-terminal amphipathic α-helix. Anti-C-terminal antibodies strongly detected a ~13 kDa band in horse tears that was validated by mass spectrometry. In human tears, the same antibody detected uncleaved lacritin (~24 kDa) strongly and C-terminal fragments of ~13 and ~11 kDa weakly. Anti-N-terminal antibodies were slightly reactive with a ~24 kDa horse antigen and showed no reaction with the anti-C-terminal-reactive ~13 kDa species. Similar respective levels of horse C-terminal versus N-terminal immunoreactivity were apparent by ELISA. Conclusions. Lacritin is present in horse tears, largely as a C-terminal fragment homologous to the mitogenic and bactericidal region in human lacritin, suggesting potential benefit in corneal wound repair. 相似文献
1000.
Maria?D.?RaduEmail author Henning?Kelb?k Erik?J?rgensen Steffen?Helqvist Bettina?L?jmand Thomas?Engstr?m Kari?I.?Saunam?ki 《Current cardiovascular imaging reports》2014,7(9):9286
Optical coherence tomography (OCT) is a high-resolution technology for imaging of biological tissues that has shown tremendous potential for intracoronary use. Based on near-infrared light rather than ultrasound, catheter-based OCT provides cross-sectional images of the vessel wall and related devices in a histology-like manner. At present, OCT is primarily being used in research to better characterize and understand the pathophysiology of vulnerable plaques and to study the acute and long-term effects of coronary stent implantation. The present review provides the interventional cardiologist with a summary of the clinical research involving OCT, with an emphasis on specific challenges and how these may be overcome to promote a shift from the mainly research application of this technology, to a wider adoption in clinical practice. 相似文献