全文获取类型
收费全文 | 88598篇 |
免费 | 6793篇 |
国内免费 | 2733篇 |
专业分类
耳鼻咽喉 | 874篇 |
儿科学 | 1537篇 |
妇产科学 | 1513篇 |
基础医学 | 11171篇 |
口腔科学 | 1627篇 |
临床医学 | 9658篇 |
内科学 | 16309篇 |
皮肤病学 | 1869篇 |
神经病学 | 5626篇 |
特种医学 | 2820篇 |
外国民族医学 | 11篇 |
外科学 | 9976篇 |
综合类 | 8647篇 |
现状与发展 | 8篇 |
一般理论 | 18篇 |
预防医学 | 6626篇 |
眼科学 | 2131篇 |
药学 | 8427篇 |
68篇 | |
中国医学 | 3350篇 |
肿瘤学 | 5858篇 |
出版年
2024年 | 227篇 |
2023年 | 1123篇 |
2022年 | 2780篇 |
2021年 | 4179篇 |
2020年 | 2748篇 |
2019年 | 2744篇 |
2018年 | 3038篇 |
2017年 | 2610篇 |
2016年 | 2591篇 |
2015年 | 3710篇 |
2014年 | 4719篇 |
2013年 | 5373篇 |
2012年 | 7840篇 |
2011年 | 7995篇 |
2010年 | 5127篇 |
2009年 | 4376篇 |
2008年 | 5608篇 |
2007年 | 5408篇 |
2006年 | 4756篇 |
2005年 | 4383篇 |
2004年 | 3422篇 |
2003年 | 3114篇 |
2002年 | 2551篇 |
2001年 | 1162篇 |
2000年 | 1100篇 |
1999年 | 900篇 |
1998年 | 544篇 |
1997年 | 479篇 |
1996年 | 395篇 |
1995年 | 343篇 |
1994年 | 286篇 |
1993年 | 221篇 |
1992年 | 268篇 |
1991年 | 245篇 |
1990年 | 220篇 |
1989年 | 176篇 |
1988年 | 150篇 |
1987年 | 133篇 |
1986年 | 126篇 |
1985年 | 98篇 |
1984年 | 79篇 |
1983年 | 79篇 |
1982年 | 88篇 |
1981年 | 87篇 |
1980年 | 57篇 |
1979年 | 71篇 |
1978年 | 39篇 |
1977年 | 48篇 |
1976年 | 44篇 |
1974年 | 31篇 |
排序方式: 共有10000条查询结果,搜索用时 0 毫秒
21.
本研究经杀菌试验和免疫后保护力试验探讨小鼠巨噬细胞在抗白色念珠菌感染中的作用,结果表明白色念珠菌酵母形体对巨噬细胞杀伤作用的抵抗力及对小鼠的毒力均较菌丝形体强。小鼠体内不同部位巨噬细胞杀伤白色念珠菌的作用不同,脾脏巨噬细胞作用大于腹腔残存巨噬细胞。经白色念珠菌活菌静脉免疫后脾巨噬细胞杀白色念珠菌作用增强,但其对再感染的抵抗力不增强。 相似文献
22.
23.
24.
石刻雕塑作业劳动卫生学调查及实验研究 总被引:1,自引:0,他引:1
测定了石雕作业粉尘浓度,几何平均浓度为82.35~3.67mg/m3。工人职业性健康检查结果,接尘工人的咽部充血、咳嗽、咯痰检出率高于对照组;肺功能低下的检出率也高于对照组。该厂自1972年以来发生尘肺患者17例,其病情发展和晋期缓慢,发病工龄长。动物实验研究表明,石雕粉尘有轻微的致纤维化作用。 相似文献
25.
Mnica De la Fuente Juan Jos Garrido Rosa María Arahuetes Angel Hernanz 《Journal of neuroimmunology》1993,42(1)
The neuropeptides neurotensin and neuromedin N (from 10−12 M to 10−9 M) have been showed in this study to stimulate significantly in vitro several steps of the phagocytic process: adherence to substrate, chemotaxis, ingestion of inert particles (latex beads) and production of superoxide anion measured by nitroblue tetrazolium reduction in resting peritoneal macrophages from BALB/c mice. A dose-response relationship was observed, with a maximal stimulation of the phagocytic process at 10−11 M. The two neuropeptides induced no change of intracellular cyclic AMP in murine macrophages. Moreover, adherence and chemotaxis decreased significantly in the presence of EGTA (1 mM), a chelator of extracellular Ca2+, or ryanodine (0.5 mM), a blocker of a Ca2+-gated channel from the endoplasmic reticulum, in both controls and samples with the addition of neurotensin or neuromedin N. These results suggest that there is no relation between the cAMP messenger system and the phagocytic process stimulation in murine peritoneal macrophages by neurotensin or neuromedin N. In addition, the results observed with EGTA and ryanodine could indicate that these two neuropeptides produce their effects through an increase of intracellular Ca2+ concentration. 相似文献
26.
Juan C. Kupferman Charles L. Stewart Frederick J. Kaskel Richard N. Fine 《Pediatric nephrology (Berlin, Germany)》1996,10(2):143-146
Renal and urological anomalies in Down syndrome (DS) have received little attention compared with the nephrourological findings described in other chromosomal abnormalities. Renal hypoplasia, hydroureteronephrosis, ureterovesical and ureteropelvic junction obstruction, and vesicoureteral reflux, but not posterior urethral valves, have been associated with DS. We report the occurrence of posterior urethral valves in three male infants with DS at a single institution. All had multiple urological procedures for correction or palliation of obstruction. Children with DS may have an increased risk for developing posterior urethral valves and obstructive uropathy. Furthermore, they may also develop chronic renal failure secondary to posterior urethral valves. Therefore, we suggests that infants with DS be screened with ultrasonography for renal and urological abnormalities early in life and, if abnormal, a contrast voiding cystourethrogram be performed to rule out posterior urethral valves or other bladder or urethral abnormalities. A review of the renal and urological anomalies in DS reported in the literature since 1960 is presented. 相似文献
27.
不同术后镇痛模式对红细胞免疫功能的影响 总被引:4,自引:1,他引:3
目的探讨不同术后镇痛模式对红细胞免疫功能的影响。方法50例妇科手术患者,按术后不同镇痛模式分为硬膜外自控镇痛(PCEA)组和静脉自控镇痛(PCIA)组。并分别于术前、术后1、3、7 d采静脉血样检测红细胞C3b受体花环率(RCR)、红细胞免疫复合物花环率(RICR)、红细胞免疫粘附促进因子(RFER)和红细胞免疫粘附抑制因子(RFIR)。结果与术前比,PCEA组术后1 d RCR、RFER显著上升(P<0.05),RFIR显著下降(P<0.05),术后3 d RCR、RFER仍显著上升(P<0.05),而RICR显著下降(P<0.05);PCIA组术后1 d RCR、RFER显著下降(P<0.05),RFIR、RICR显著上升(P<0.05);PCIA组术后1、3 d RCR、RFER比PCEA组显著降低(P<0.05),而RICR显著上升(P<0.05);两组各参数在术后7 d基本恢复至术前水平。结论PCEA对红细胞免疫功能的稳定和恢复作用明显强于PCIA。 相似文献
28.
Alicia Gómez-Barrio David Montero-Pereira Juan J. Nogal-Ruiz José A. Escario Susana Muelas-Serrano Vladimir V. Kouznetsov Leonor Y. Vargas Méndez Juan M. Urbina Gonzáles Carmen Ochoa 《Acta parasitologica / Witold Stefański Institute of Parasitology, Warszawa, Poland》2006,51(1):73-78
A study of some antiparasitic properties of several homoallylamines and related tetrahydroquinolines and quinolines, previously
described, was carried out using in vitro activity assays against the epimastigote form of Trypanosoma cruzi and against Trichomonas vaginalis. Unspecific cytotoxicity against murine macrophages was also studied. Although the antichagasic and trichomonacidal activities
are not comparable to those of the standard drugs, nifurtimox and metronidazole, some of the compounds exhibit an interesting
specific antiparasitic activity. 相似文献
29.
30.
Dong Hwee Kim Yoon Kyoo Kang Miriam Hwang Ho Sung Jo Ki Hoon Kim 《Clinical neurophysiology》2004,115(5):1021-1026
OBJECTIVE: To evaluate the usefulness of the TenElectrodes, a new stimulator for inching test, in the diagnosis and localization of ulnar neuropathy at the elbow (UNE). METHODS: Sixty-two ulnar nerves in 40 control subjects and 24 ulnar nerves in 23 patients with typical symptoms and signs of UNE were studied. The inching test of ulnar motor nerve using TenElectrodes was done along 8 cm across the elbow in the extended position. RESULTS: In the inching test of the control group, the mean segmental latency difference was 0.19+/-0.08 ms. Maximal latency difference over a 1 cm segment did not exceed 0.40 ms in any of the controls but exceeded 0.5 ms or more in all clinical UNE patients. In all UNE patients, the lesion sites were identified by the inching test using TenElectrodes: the retroepicondylar groove (54.2%), the humeroulnar arcade (29.2%), and dual compression (16.6%). CONCLUSIONS: TenElectrodes is a useful stimulator for the inching test in the diagnosis of UNE. The precise localization of compression was possible in all patients with UNE and the most common site was the retroepicondylar groove. 相似文献