子宫内膜异位症与nm23-H1基因之间关系的研究

目的　研究nm2 3 H1基因在子宫内膜异位症发生中的作用。方法　采用免疫组化方法研究 2 5例子宫内膜异位症患者的病理组织和 2 2例正常子宫内膜组织中的nm2 3 H1蛋白的表达情况 ;用RT PCR方法研究 2 5例子宫内膜异位症患者的病理组织中nm2 3 H1基因的mRNA的表达情况。结果　子宫内膜异位症组中的nm2 3 H1蛋白表达水平明显低于对照组 (P <0 .0 1) ,子宫内膜异位症组中 ,nm2 3 H1蛋白表达与mRNA表达的结果无显著性差异 (P >0 .0 5 )。结论　nm2 3 H1基因在子宫内膜异位症的发生发展中起一定的作用。     

出生缺陷与电磁辐射和食物链关系分析

目的探讨出生缺陷与电磁辐射和食物链的关系。方法选择195例出生缺陷患儿母亲作为研究组,195例健康儿母亲为对照组,对两组孕期居住环境及使用手机、电脑、电磁炉、微波炉频率和饮食习惯等进行调查,并检测分娩时母血雌激素、孕酮、睾酮水平。结果研究组居住靠近变压器、电视塔、通讯转播塔比例高于对照组（P均〈0.05）,孕期食用人工饲料喂养的家禽、牲畜、鱼等的频率高于对照组（P均〈0.05）;研究组孕期使用手机、电脑、电磁炉、微波炉、观看电视的频率高于对照组（P均〈0.05）。结论电磁辐射和食用人工饲料喂养的家禽、牲畜、鱼类等肉食对出生缺陷可能有影响。     

Linux操作系统在医学院校的教学实践

本文强调了Linux教学实施的必要性,着重从Linux系统教学实践和Linux系统下的软件应用方面总结了我校实施Linux系统的教学实践过程,并对教学方法展开了讨论。     

培养创新型临床医学人才的思考

文章从创新及创新型人才的概念入手，通过调研指出，目前临床医学人才培养存在的主要问题，提出在新时期要转变教育教学观念、强化创新意识教育、增强创新思维训练、着力创新人格塑造，以培养创新型临床医学人才。     

浅谈医疗设备临床使用安全风险管理

本文针对目前医疗设备临床使用与管理现状,提出了医疗设备风险管理概念。基于医疗设备在临床使用中的风险分析与评估,阐述了相应的风险控制与管理,通过一系列有效的质控措施,保证医疗设备的安全有效运转。     

Hodgkin Lymphoma after Disseminated Mycobacterium genavense Infection,Germany

Mycobacterium genavense infection, a rare nontuberculous mycobacteria infection, occurs in heavily immunocompromised patients (i.e., those with advanced HIV disease, genetic disorders, or acquired immunologic disorders and those undergoing immunosuppressive therapy). We report a case of disseminated M. genavense infection preceding Hodgkin lymphoma in a patient without obvious risk factors for this infection.     

人工神经网络技术诊断附件包块良恶性的可行性研究

目的 探索运用计算机智能人工神经网络技术建立诊断模型来判断附件包块良恶性的可行性.方法 180例附件包块患者随机分为训练组和测试组.训练组结合统计学多因素分析方法筛选出的参数建立人工神经网络诊断模型;测试组通过ROC曲线分析比较与恶性风险指数模型诊断性能的高低.结果 18项指标中单因素分析有14项指标对判断附件包块的性质有意义（P＜0.05）.由统计学多因素分析选出的参数（年龄、血清CA125、包块内壁突起、腹水及血流平均速度）共5项作为神经网络模型输入层参数,建立模型.ROC曲线证实神经网络模型较恶性风险指数模型的诊断性能高（P＜0.05）.结论 人工神经网络诊断模型对附件包块良恶性判断有良好的诊断性能.     

一种纯机械式无电源的输液泵动力源

目的设计一种动力源,驱动纯机械式无电源输液泵。方法通过气源、磁场、发条三种能量动力源的比较,采用发条作为储能媒介,设计发条定时器;通过无固有周期擒纵调速器,保证发条匀速稳定输出,带动输液泵蠕动泵头的转动。结果发条定时器储能、释放能量驱动匀速机匀速运输,取代传统电机驱动蠕动泵头。结论与气源、磁场相比较,发条作为动力源具有易控制、维护简单、耐热、耐腐蚀等优点。     

miR-211对高糖诱导下晶状体上皮细胞氧化应激反应的调控作用

目的 探讨miR-211对高糖诱导下晶状体上皮细胞氧化应激反应的调控作用及其可能存在的作用机制.方法 将HLEC-B3细胞在含不同浓度(0、10、20、40 mmol/L)葡萄糖的培养基中培养48 h,RT-PCR检测细胞miR-211表达,Western blot检测细胞SIRT1蛋白表达,试剂盒检测总抗氧化能力(T...     

Corneal densitometry in patients with arcus senilis and its correlation with serum lipid levels

Purpose:To evaluate corneal densitometry (CD) of patients with arcus senilis (AS) and its association with the serum lipid markers.Methods:This is a cross-sectional, case-control study. The AS diagnosis was made clinically. Forty-five eyes of 45 patients with AS and 38 eyes of 38 age-matched control subjects with no noticeable AS were enrolled in the study. All participants underwent detailed ophthalmologic examination along with corneal Scheimpflug imaging with CD measurement. The evaluated serum lipid markers of the participants included total cholesterol, triglyceride, low-density lipoprotein (LDL), high-density lipoprotein (HDL), and very-low-density lipoprotein (VLDL). The Spearman correlation analysis was used to correlate the serum lipid values and the CD. P < 0.05 was defined as statistically significant.Results:The male to female ratio was 26/19 and 14/24 in the study and control groups, respectively (P = 0.057). The mean age was 59.56 ± 8.7 and 56.47 ± 8.6 years in the study and control groups, respectively (P = 0.117). The mean total CD values in the zones extending from 2 to 12 mm were higher in the study group than in the control group (P < 0.001). The serum HDL level was found to be significantly decreased in the study group compared to the control group (P = 0.048 and Z = −1.976). There was a significant positive correlation between the serum triglyceride level and the CD value of the outermost zone (10–12 mm) (r = 0.334 and P = 0.025).Conclusion:The CD of patients with AS was found to increase not only in the peripheral zone but also in the cornea’s paracentral zone compared to the healthy controls. The serum triglyceride level should give an insight into the intensity of arcus senilis. The serum HDL levels were decreased in patients with AS.