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931.
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933.
Prognostic value of advanced lung cancer inflammation index in head and neck squamous cell carcinoma
Jank Bernhard J. Kadletz Lorenz Schnöll Julia Selzer Edgar Perisanidis Christos Heiduschka Gregor 《European archives of oto-rhino-laryngology》2019,276(5):1487-1492
European Archives of Oto-Rhino-Laryngology - The advanced lung cancer inflammation index (ALI) is a useful tool for prediction of outcome in several malignancies. However, to date, its significance... 相似文献
934.
Kristin Julia Glaas Marcel Fabian Schipper Jörg Klenzner Thomas Eysel-Gosepath Katrin Jansen Philipp Franz Matthias Schäfer Ralf 《European archives of oto-rhino-laryngology》2019,276(9):2441-2447
European Archives of Oto-Rhino-Laryngology - Since the 1980s, health-related quality of life (HRQOL) has been recognized in the assessment of medical treatment. To determine the health-related... 相似文献
935.
Aronoff Justin M. Staisloff Hannah E. Kirchner Abbigail Lee Daniel H. Stelmach Julia 《Journal of the Association for Research in Otolaryngology》2019,20(6):595-603
Journal of the Association for Research in Otolaryngology - There is often a mismatch for bilateral cochlear implant (CI) users between the electrodes in the two ears that receive the same... 相似文献
936.
Federico Pappalardo Evgenij Potapov Antonio Loforte Michiel Morshuis David Schibilsky Daniel Zimpfer Julia Riebandt Christian Etz Matteo Attisani Mauro Rinaldi Assad Haneya Faiz Ramjankhan Dirk Donker Ulrich P Jorde Daniel Lewin Radi Wieloch Rafael Ayala Jochen Cremer Letizia Bertoldi Michael Borger Artur Lichtenberg Jan Gummert Diyar Saeed the Durable MCS after ECLS study group 《Interactive Cardiovascular and Thoracic Surgery》2022,34(4):676
Open in a separate window OBJECTIVESImplanting a durable left ventricular assist device (LVAD) in a patient on extracorporeal life support (ECLS) is challenging. The goal of this study was to compare the results of patients from a European registry who had a durable LVAD implanted with or without transition from ECLS to cardiopulmonary bypass (CPB).METHODSA total of 531 patients on ECLS support who had an LVAD implant between January 2010 and August 2018 were analysed; after 1:1 propensity score matching, we identified and compared 175 patients in each group.RESULTSThe duration of preoperative ECLS was 7 [standard deviation (SD) 6] vs 7 (SD 6) days in patients with or without CPB (P = 0.984). The surgical time was longer in the CPB group [285 (SD 72) vs 209 [SD 75] min; P ≤ 0.001). The postoperative chest tube output was comparable [1513 (SD 1311) vs 1390 (SD 1121) ml; P = 0.3]. However, re-exploration for bleeding was necessary in 41% vs 29% of patients with or without CPB (P = 0.01) and a significantly higher number of packed red blood cells and fresh frozen plasma [8 (SD 8) vs 6 (SD 4) units; P = 0.001 and 6 (SD 7) vs 5 (SD 5) units; P = 0.03] were administered to patients operated on with CPB. A postoperative mechanical right ventricular support device was necessary in 50% vs 41% of patients (P = 0.08). The stroke rate was not significantly different (P 0.99). No difference in survival was observed.CONCLUSIONSOmitting CPB for an LVAD implant in patients on ECLS is safe and results in shorter operating time, less re-exploration for bleeding and fewer blood products. However, no survival benefit is observed. 相似文献
937.
Wiebke Schlrmann Julia A. Bockwoldt Sabine M. Hübner Elisa Wittwer Sarah Reiners Stefan Lorkowski Christine Dawczynski Matthias A. Ehrmann Michael Glei 《Nutrients》2022,14(7)
The aim of the present study was to examine β-glucan production and the potential prebiotic and chemopreventive effects of wheat and rye sourdoughs and breads generated with wild-type and non-β-glucan-forming isogenic mutant strains of Levilactobacillus brevis and Pediococcus claussenii. Sourdough and bread samples were subjected to in vitro digestion and fermentation. Fermentation supernatants (FS) and pellets (FP) were analyzed (pH values, short-chain fatty acids (SCFA), ammonia, bacterial taxa) and the effects of FS on LT97 colon adenoma cell growth, viability, caspase-2 and -3 activity, genotoxic and antigenotoxic effects and on gene and protein expression of p21, cyclin D2, catalase and superoxide dismutase 2 (SOD2) were examined. Concentrations of SCFA were increased and concentrations of ammonia were partly reduced in the FS. The relative abundance of Bifidobacteriaceae was increased in all FPs. Treatment with FS reduced the growth and viability of LT97 cells and significantly increased caspase-2 and -3 activities without exhibiting genotoxic or antigenotoxic effects. The p21 mRNA and protein levels were increased while that of cyclin D2 was reduced. Catalase and SOD2 mRNA and protein expression were marginally induced. The presented results indicate a comparable chemopreventive potential of wheat and rye sourdoughs and breads without an additional effect of the formed β-glucan. 相似文献
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939.
Vincent van de Ven Chanju Lee Julia Lifanov Sarah Kochs Henk Jansma Peter De Weerd 《Hippocampus》2020,30(9):926-937
The hippocampus and dorsal striatum are both associated with temporal processing, but they are thought to play distinct roles. The hippocampus has been reported to contribute to storing temporal structure of events in memory, whereas the striatum contributes to temporal motor preparation and reward anticipation. Here, we asked whether the striatum cooperates with the hippocampus in processing the temporal context of memorized visual associations. In our task, participants were trained to implicitly form temporal expectations for one of two possible time intervals associated to specific cue‐target associations, and subsequently were scanned using ultra‐high‐field 7T functional magnetic resonance imaging. During scanning, learned temporal expectations could be violated when the pairs were presented at either the associated or not‐associated time intervals. When temporal expectations were met during testing trials, activity in left and right hippocampal subfields and right putamen decreased, compared to when temporal expectations were not met. Further, psycho‐physiological interactions showed that functional connectivity between left hippocampal subfields and caudate decreased when temporal expectations were not met. Our results indicate that the hippocampus and striatum cooperate to process implicit temporal expectation from mnemonic associations. Our findings provide further support for a hippocampal‐striatal network in temporal associative processing. 相似文献
940.