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131.
Heidi E. Hagerott Sakil Kulkarni Ricardo Restrepo Jesse Reeves-Garcia 《Pediatric radiology》2014,44(7):810-815
Background
Umbilical venous catheterization is a common procedure performed in neonatal intensive care units. Hepatic collections due to inadvertent extravasation of parenteral nutrition into the liver have been described previously in literature.Objective
To recognize the clinicoradiologic features and treatment options of hepatic collections due to inadvertent extravasation of parenteral nutrition fluids caused by malpositioning of umbilical venous catheter (UVC) in the portal venous system.Materials and methods
This is a case series describing five neonates during a 6-year period at a single tertiary care referral center, with extravasation of parenteral nutrition into the liver parenchyma causing hepatic collections.Results
All five neonates receiving parenteral nutrition presented with abdominal distension in the second week of life. Two out of five (40%) had anemia requiring blood transfusion and 3/5 (60%) had hemodynamic instability at presentation. Ultrasound of the liver confirmed the diagnosis in all the cases. Three of the five (60%) cases underwent US-guided aspiration of the collections, one case underwent conservative management and one case required emergent laparotomy due to abdominal compartment syndrome. US used in follow-up of these cases revealed decrease in size of the lesions and/or development of calcifications.Conclusion
Early recognition of this complication, prompt diagnosis with US of liver and timely treatment can lead to better outcome in newborns with hepatic collections secondary to inadvertent parenteral nutrition infusion via malposition of UVC. 相似文献132.
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134.
BackgroundThe patient–clinician interaction is a site at which defensive practice could occur, when clinicians provide tests, procedures and treatments mainly to reduce perceived legal risks, rather than to advance patient care. Defensive practice is a driver of low‐value care and exposes patients to the risks of unnecessary interventions. To date, patient perspectives on defensive practice and its impacts on them are largely missing from the literature. This exploratory study conducted in Australia aimed to examine the views and experiences of healthcare consumer representatives in this under‐examined area.MethodsSemi‐structured interviews were conducted with healthcare consumer representatives involved in healthcare consumer advocacy organisations in Australia. Data were transcribed and analysed thematically.ResultsNine healthcare consumer representatives participated. Most had over 20 years of involvement and advocacy in healthcare, including personal experiences as a patient or carer and/or formal service roles on committees or complaint bodies for healthcare organisations. Participants uniformly viewed defensive practice as having a negative impact on the clinician–patient relationship. Themes identified the importance of fostering patient–clinician partnership, effective communication and informed decision‐making. The themes support a shift from the concept of defensive practice to preventive practice in partnership, which focuses on the shared interests of patients and clinicians in achieving safe and high‐value care.ConclusionThis Australian study offers healthcare consumers'' perspectives on the impacts of defensive practice on patients. The findings highlight the features of clinician–patient partnership that will help to improve communication and decision‐making, and prevent the defensive provision of low‐value care.Patient or Public ContributionHealthcare consumer representatives were involved as participants in this study. 相似文献
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136.
Jesse Mez MD MS Daniel H. Daneshvar MD PhD Bobak Abdolmohammadi BA Alicia S. Chua MS Michael L. Alosco PhD Patrick T. Kiernan BA Laney Evers BA Laura Marshall BA Brett M. Martin MS Joseph N. Palmisano MS Christopher J. Nowinski PhD Ian Mahar PhD Jonathan D. Cherry PhD Victor E. Alvarez MD Brigid Dwyer MD Bertrand R. Huber MD PhD Thor D. Stein MD PhD Lee E. Goldstein MD PhD Douglas I. Katz MD Robert C. Cantu MD Rhoda Au PhD Neil W. Kowall MD Robert A. Stern PhD Michael D. McClean MS ScD Jennifer Weuve MPH ScD Yorghos Tripodis PhD Ann C. McKee MD 《Annals of neurology》2020,87(1):116-131
137.
Margaret A. DiGuardo Jaime I. Davila Rory A. Jackson Asha A. Nair Numrah Fadra Kay T. Minn Mazen A. Atiq Shabnam Zarei Joseph H. Blommel Shannon M. Knight Jin Jen Bruce W. Eckloff Jesse S. Voss Kandelaria M. Rumilla Sarah E. Kerr Dora M. Lam-Himlin Andrew M. Bellizzi Rondell P. Graham Kevin C. Halling 《The Journal of molecular diagnostics : JMD》2021,23(5):555-564
138.
Shivali Sarawgi Mary E. Oglesby Jesse R. Cougle 《Journal of behavior therapy and experimental psychiatry》2013,44(4):456-462
Background and objectivesResearch suggests a relationship between intolerance of uncertainty (IU) and obsessive-compulsive disorder (OCD), though this has been limited to self-report measures of OCD symptoms. The current investigation examined the relationship between IU and multiple symptom domains of OCD using self-report and in vivo assessments of OC symptoms.MethodsFive separate studies are presented in which undergraduate students (N = 603) were administered a self-report measure of IU and tasks related to either ordering and arranging, checking, washing, contamination avoidance, or neutralization.ResultsIntolerance of uncertainty was found to be significantly related to each self-report measure of the OCD symptom domains (ps < .01). Further, IU was predictive of performance on all in vivo tasks (ps < .05) except one concerning neutralizing/harm-related obsessions.LimitationsThis study relied on an unselected sample and was correlational in design.ConclusionsThe current study demonstrates that IU is related to multiple OC symptom dimensions. Future experimental research is warranted to evaluate the causal role of IU in OCD. 相似文献
139.
Fann JR Thomas-Rich AM Katon WJ Cowley D Pepping M McGregor BA Gralow J 《General hospital psychiatry》2008,30(2):112-126
OBJECTIVE: While many breast cancer patients experience "normal" distress, there is a subset who experience clinically significant depression. We examined the current knowledge about the prevalence, impact and treatment of major depression in women with breast cancer. METHOD: We reviewed the evidence for the prevalence of depression in women with breast cancer from the last 20 years and summarized the medical literature on the pharmacology and psychotherapy of depression in this population. RESULTS: Despite evidence that depression significantly impacts quality of life in breast cancer patients, few studies focus on the epidemiology and treatment of major depression. Treatment studies have focused on distress and mixed depressive states, with resulting lack of replicable studies showing treatment efficacy. Potential biological and psychosocial determinants of major depression following breast cancer are discussed in a proposed model. The need for further research on the epidemiology and treatment of major depression in this population is proposed. CONCLUSION: Major depression is a frequent but underrecognized and undertreated condition among breast cancer patients, which causes amplification of physical symptoms, increased functional impairment and poor treatment adherence. More research on the epidemiology and treatment of major depression in this population is needed. 相似文献
140.
Sarah E. Henderson Jesse R. Lowe Mauro A. Tudares Michael S. Gold Alejandro J. Almarza 《Archives of oral biology》2015