全文获取类型
收费全文 | 145561篇 |
免费 | 48350篇 |
国内免费 | 648篇 |
专业分类
耳鼻咽喉 | 2704篇 |
儿科学 | 5456篇 |
妇产科学 | 1982篇 |
基础医学 | 26398篇 |
口腔科学 | 6242篇 |
临床医学 | 18796篇 |
内科学 | 36936篇 |
皮肤病学 | 9587篇 |
神经病学 | 18850篇 |
特种医学 | 6346篇 |
外科学 | 22523篇 |
综合类 | 1308篇 |
现状与发展 | 3篇 |
一般理论 | 52篇 |
预防医学 | 8413篇 |
眼科学 | 3494篇 |
药学 | 11528篇 |
中国医学 | 1553篇 |
肿瘤学 | 12388篇 |
出版年
2023年 | 553篇 |
2022年 | 1426篇 |
2021年 | 3585篇 |
2020年 | 6095篇 |
2019年 | 12178篇 |
2018年 | 11813篇 |
2017年 | 12590篇 |
2016年 | 13860篇 |
2015年 | 14392篇 |
2014年 | 14883篇 |
2013年 | 15839篇 |
2012年 | 9860篇 |
2011年 | 9534篇 |
2010年 | 11976篇 |
2009年 | 8000篇 |
2008年 | 6050篇 |
2007年 | 4858篇 |
2006年 | 4530篇 |
2005年 | 4066篇 |
2004年 | 3508篇 |
2003年 | 3134篇 |
2002年 | 2976篇 |
2001年 | 2254篇 |
2000年 | 2119篇 |
1999年 | 1454篇 |
1998年 | 532篇 |
1997年 | 480篇 |
1996年 | 388篇 |
1995年 | 383篇 |
1994年 | 338篇 |
1993年 | 336篇 |
1992年 | 758篇 |
1991年 | 791篇 |
1990年 | 671篇 |
1989年 | 722篇 |
1988年 | 700篇 |
1987年 | 706篇 |
1986年 | 600篇 |
1985年 | 585篇 |
1984年 | 464篇 |
1983年 | 395篇 |
1982年 | 280篇 |
1981年 | 251篇 |
1980年 | 231篇 |
1979年 | 355篇 |
1978年 | 288篇 |
1977年 | 221篇 |
1974年 | 240篇 |
1973年 | 256篇 |
1972年 | 211篇 |
排序方式: 共有10000条查询结果,搜索用时 15 毫秒
11.
Jakub Pazdrowski Aleksandra Daczak‐Pazdrowska Adriana Polaska Joanna Ka
mierska Wojciech Barczak Mateusz Szewczyk Pawe Golusiski Zygmunt Adamski Ryszard aba Wojciech Golusiski 《Skin research and technology》2019,25(6):857-861
Radiodermatitis is one of the commonest side effects of radiotherapy. They are usually assessed by semi‐quantitative clinical scores, which are not validated and may be subject to inter‐observer variability. A few previous studies suggested that high‐frequency ultrasonography (HF‐USG) is useful in the assessment of the acute phase of radiation dermatitis in breast cancer patients. (a) To monitor skin changes by HF‐USG during the course of radiotherapy due to head and neck cancers, and (b) to determine whether there is any connection between skin sonograms and the skin scoring criteria. This prospective, observational study includes patients diagnosed with head and neck cancers, treated with radiotherapy or concomitant chemoradiation. The final analysis includes six patients. In every patient, the HF‐USG as well as dermatological assessment (target lesion score—TLS and CACE v. 4.0) were performed 4×: before, in the middle, day after, and 3 months after radiotherapy. There were significant differences between non‐irradiated skin thickness and thickness of skin with clinically obvious radiodermatitis (TLS grade 1‐4; P < .0001), as well as between irradiated, unchanged skin thickness (TLS grade 0) and thickness of skin with clinically obvious radiodermatitis (TLS grade 1‐4; P = .0002). There was no significant difference between non‐irradiated and irradiated, unchanged skin thickness (TLS grade 0; P = .9318). In four patients, we demonstrated subepidermal low echogenic band (SLEB). HF‐USG can be useful tool to noninvasive and objective assessment of skin changes during radiotherapy. 相似文献
12.
Jean‐Franois Etter 《Addiction (Abingdon, England)》2019,114(12):2252-2256
13.
14.
Moderate sedatives have been increasingly used to improve patient comfort during flexible bronchoscopy (FB). However, routine use of moderate sedation during FB is controversial because its efficacy and safety are not well established.This study aims to evaluate the efficacy and safety of moderate sedation during FB.A search was made of Medline, EMBASE, and the Cochrane Library to May 2014.Randomized controlled trials (RCTs) and quasi-RCTs were included.The main analysis was designed to examine the efficacy of moderate sedation during FB in sedation than no-sedation.The willingness to repeat FB was significantly more in sedation than no-sedation (odds ratio [OR] 2.30; 95% confidence interval [CI] 1.11–4.73; P = 0.02; I2 = 22.5). The duration of FB was shorter in sedation group than no-sedation group (standardized mean difference [SMD] −0.21; 95% CI −0.38 to −0.03; P = 0.02; I2 = 78.3%). Event of hypoxia was not significantly different between sedation and no-sedation groups (OR 0.86; 95% CI 0.42–1.73; P = 0.67; I2 = 0%). The SpO2 during procedure was not different between sedation and no-sedation groups (SMD −0.14; 95% CI −0.37 to 0.08; P = 0.21; I2 = 49.9%). However, in subgroup analysis without supplemental oxygen, the SpO2 was significantly lower in sedation than no-sedation group (SMD −0.45; 95% CI −0.78 to −0.11; P = 0.01; I2 = 0.0%).According to this meta-analysis, moderate sedation in FB would be useful in patients who will require repeated bronchoscopies as well as safe in respiratory depression. To our knowledge, although the various sedative drugs are already used in the real field, this analysis was the first attempt to quantify objective results. We anticipate more definite and studies designed to elucidate standardized outcomes for moderate sedation in FB. 相似文献
15.
Andy KH Lim 《World journal of gastroenterology : WJG》2020,26(10):1020-1028
Rhabdomyolysis is a syndrome of skeletal muscle injury with release of cellular constituents such as potassium,phosphate,urate and intracellular proteins such as myoglobin into the circulation,which may cause complications including acute kidney injury,electrolyte disturbance and cardiac instability.Abnormal liver function tests are frequently observed in cases of severe rhabdomyolysis.Typically,there is an increase in serum aminotransferases,namely aspartate aminotransferase and alanine aminotransferase.This raises the question of liver injury and often triggers a pathway of investigation which may lead to a liver biopsy.However,muscle can also be a source of the increased aminotransferase activity.This review discusses the dilemma of finding abnormal liver function tests in the setting of muscle injury and the potential implications of such an association.It delves into some of the clinical and experimental evidence for correlating muscle injury to raised aminotransferases,and discusses pathophysiological mechanisms such as oxidative stress which may cause actual liver injury.Serum aminotransferases lack tissue specificity to allow clinicians to distinguish primary liver injury from muscle injury.This review also explores potential approaches to improve the accuracy of our diagnostic tools,so that excessive or unnecessary liver investigations can be avoided. 相似文献
16.
17.
Ángel Becerra Héctor Trujillo Lucía Valencia Aurelio Rodríguez‐Pérez 《Brazilian Journal of Anesthesiology》2019,69(2):200-203
Background and objectives
A prompt and effective management of trauma patient is necessary. The aim of this case report is to highlight the importance of intraoperative echocardiography as a useful tool in patients suffering from refractory hemodynamic instability no otherwise explained.Case report
A 41 year‐old woman suffered a car accident. At the emergency department, no abnormalities were found in ECG or chest X‐ray. Abdominal ultrasound revealed the presence of abdominal free liquid and the patient was submitted to urgent exploratory laparotomy. Nevertheless, she persisted suffering arterial hypotension and metabolic acidosis. Looking for the reason of her hemodynamic instability, intraoperative transthoracic echocardiography was performed, finding out the presence of pericardial effusion. Once the cardiac surgeon extracted pericardial clots, patient's situation improved clinically and analytically.Conclusion
Every anesthesiologist should be able to use the intraoperative echocardiography as an effective tool in order to establish the appropriate measures to promote the survival of patients suffering severe trauma. 相似文献18.
19.