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High mortality with an intraperitoneal antiadhesive in the rat 总被引:2,自引:0,他引:2
R J Felton D W Tuggle A L Milewicz C K Shock D V Taylor T A Perkins W P Tunell 《Current surgery》1990,47(6):444-446
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Jack T. Trevors 《Environmental toxicology》1987,2(3):283-291
Samples taken from an activated sludge reactor used for the biodegradation of metal cutting fluids were studied for the presence of plasmid-containing bacteria. Twenty different bacterial isolates contained one or more plasmids. After numerous transfers of the isolates through LB broth, 55% of the plasmids were spontaneously lost as evidenced by agarose gel electrophoresis. Eighty percent of the isolates were resistant to one or more antibiotics, 65% resistant to two or more antibiotics, 40% resistant to three or more, 20% resistant to four or more and 5% resistant to five antibiotics. The isolates were also tested for their sensitivity to several common metals. This study has demonstrated that activated sludge is a natural reservoir for plasmid-containing bacteria involved in biodegradation of wastes. 相似文献
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Is neurogenesis reparative after status epilepticus? 总被引:1,自引:0,他引:1
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Azra Raza Harvey D. Preisler Ya Qin Li Richard A. Larson Jack Goldberg George Browman John Bennett Hans Grunwald Ralph Vogler Cathi Kukla 《American journal of hematology》1993,42(4):359-366
A pilot study was conducted of the biological characteristics of the leukemia cells of newly diagnosed patients with poor prognosis acute myelogenous leukemia (AML). This study included measurements of the pretherapy proliferative rate of the leukemia cells in vivo, assessment of differentiation in vivo during remission induction therapy, and the level of expression of the fms, myc, and IL1β genes in pretherapy leukemia cells. Short cell cycle times were characteristic of the best prognostic category and were associated with a rapid reduction in marrow leukemia cells in cytosine arabinoside (araC)-sensitive patients. Expression of c-fms was associated with rapid reduction in marrow leukemia cells during araC therapy and with a successful treatment outcome. Expression of the IL1β gene was associated with short remissions. These studies suggest that when compared to newly diagnosed standard prognosis AML, the leukemia of poor prognosis patients is more likely to exhibit long cell cycle times, low levels of fms expression, and is less likely to be associated with myeloid differentiation during remission induction therapy. © 1993 Wiley-Liss, Inc. 相似文献