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Michelle Bosquet Enlow Lucy King Hannah MC Schreier Jamie M. Howard David Rosenfield Thomas Ritz Rosalind J. Wright 《Early human development》2014
Background
Early environmental exposures may help shape the development of the autonomic nervous system (ANS) and hypothalamic–pituitary–adrenal (HPA) axis, influencing vulnerability for health problems across the lifespan. Little is known about the role of maternal sensitivity in influencing the development of the ANS in early life.Aims
To examine associations among maternal sensitivity and infant behavioral distress and ANS and HPA axis reactivity to the Repeated Still-Face Paradigm (SFP-R), a dyadic stress task.Study design
Observational repeated measures study.Subjects
Thirty-five urban, sociodemographically diverse mothers and their 6-month-old infants.Outcome measures
Changes in infant affective distress, heart rate, respiratory sinus arrhythmia (RSA), and T-wave amplitude (TWA) across episodes of the SFP-R were assessed. A measure of cortisol output (area under the curve) in the hour following cessation of the SFP-R was also obtained.Results
Greater maternal insensitivity was associated with greater infant sympathetic activation (TWA) during periods of stress and tended to be associated with greater cortisol output following the SFP-R. There was also evidence for greater affective distress and less parasympathetic activation (RSA) during the SFP-R among infants of predominantly insensitive mothers.Conclusions
Caregiving quality in early life may influence the responsiveness of the sympathetic and parasympathetic branches of the ANS as well as the HPA axis. Consideration of the ANS and HPA axis systems together provides a fuller representation of adaptive versus maladaptive stress responses. The findings highlight the importance of supporting high quality caregiving in the early years of life, which is likely to promote later health. 相似文献114.
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Pedro Luis Cepas-Guillén Isaac Pascual Eulogio Garcia Pilar Jimenez-Quevedo Alfonso Jurado-Roman Tomás Benito-González Rodrigo Estevez-Loureiro Pedro Li Dabit Arzamendi Bruno Melica Eduardo Infante de Oliveira Pedro Martín Lorenzo Felipe Fernández-Vázquez Guillermo Galeote Luis Nombela-Franco Leire Unzue Pablo Avanzas Manel Sabate Xavier Freixa 《老年心脏病学杂志》2022,19(1):90
Given the increase in life expectancy indeveloped countries,nonagenarian population will become clinically and numerically relevant in our daily routine practice in the near future.Age has been observed to exert a profound influence on the prevalence of severe mitral regurgitation (MR) in the population.[1]Mitral valve surgery remains the gold standard of care for patients with symptomatic severe MR. 相似文献
116.
Infante Jon Serrano-Cárdenas Karla M. Corral‐Juan Marc Farré Xavier Sánchez Ivelisse de Lucas Enrique M. García Antonio Martín-Gurpegui José Luis Berciano José Matilla-Dueñas Antoni 《Journal of neurology》2020,267(2):324-330
Journal of Neurology - Adolescent-onset spastic ataxia is a proposed novel phenotype in compound heterozygous carriers of an intronic mutation (c.1909 + 22G > A) in... 相似文献
117.
Maitane Garca Imanol Amayra Juan Francisco Lpez-Paz Oscar Martnez Esther Lzaro Manuel Prez Sarah Berrocoso Mohammad Al-Rashaida Jon Infante 《Cerebellum (London, England)》2020,19(3):392-400
Chiari malformation type I (CM-I) is a neurological disorder in which cerebellar tonsils are herniated through the foramen magnum into the spinal canal. A 相似文献
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Ester Orlandi MD Stefano Cavalieri MD Roberta Granata MD Piero Nicolai MD Paolo Castelnuovo MD Cesare Piazza MD Alberto Schreiber MD Mario Turri-Zanoni MD Pasquale Quattrone MD Rosalba Miceli MD Gabriele Infante PhD Fausto Sessa MD Carla Facco MD Giuseppina Calareso MD Nicola Alessandro Iacovelli MD Davide Mattavelli MD Alberto Paderno MD Carlo Resteghini MD Laura Deborah Locati MD Lisa Licitra MD Paolo Bossi MD 《The Laryngoscope》2020,130(4):857-865
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Alexandra Pérez-Soriano MD Paloma Bravo MSc Marta Soto MSc Jon Infante MD PhD Manel Fernández BTech Francesc Valldeoriola MD PhD Esteban Muñoz MD PhD Yaroslau Compta MD PhD Eduard Tolosa MD PhD Alicia Garrido MD Mario Ezquerra PhD Rubén Fernández-Santiago PhD María-José Martí MD PhD the Catalan MSA registry 《Movement disorders》2020,35(10):1873-1879
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