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Terzin V Földesi I Kovács L Pokorny G Wittmann T Czakó L 《World journal of gastroenterology : WJG》2012,18(21):2649-2653
AIM: To investigate the association between autoimmune pancreatitis (AIP) and systemic autoimmune diseases (SAIDs) by measurement of serum immunoglobulin G4 (IgG4).METHODS: The serum level of IgG4 was measured in 61 patients with SAIDs of different types who had not yet participated in glucocorticosteroid treatment. Patients with an elevated IgG4 level were examined by abdominal ultrasonography (US) and, in some cases, by computer tomography (CT).RESULTS: Elevated serum IgG4 levels (919 ± 996 mg/L) were detected in 17 (28%) of the 61 SAID patients. 10 patients had Sjögren’s syndrome (SS) (IgG4: 590 ± 232 mg/L), 2 of them in association with Hashimoto’s thyroiditis, and 7 patients (IgG4: 1388 ± 985.5 mg/L) had systemic lupus erythematosus (SLE). The IgG4 level in the SLE patients and that in patients with SS were not significantly different from that in AIP patients (783 ± 522 mg/L). Abdominal US and CT did not reveal any characteristic features of AIP among the SAID patients with an elevated IgG4 level.CONCLUSION: The serum IgG4 level may be elevated in SAIDs without the presence of AIP. The determination of serum IgG4 does not seem to be suitable for the differentiation between IgG4-related diseases and SAIDs. 相似文献
43.
Füst Ágnes Tóth Jeannette Imre László Nagy Zoltán Zsolt 《International ophthalmology》2021,41(5):1827-1834
International Ophthalmology - To observe and describe the anterior segment optical coherence tomography features of limbally localised non-malignant epithelial mass lesions Thirteen patients (age:... 相似文献
44.
Péter Monostori Gabriella F. Kocsis Zsuzsanna Ökrös Péter Bencsik Orsolya Czétényi Zoltán Kiss Balázs Gellén Csaba Bereczki Imre Ocsovszki Judit Pipis János Pálóczi Márta Sárközy Szilvia Török Ilona S. Varga István Kiss Eszter Fodor Tamás Csont Péter Ferdinandy Sándor Túri 《Clinical and experimental nephrology》2013,17(4):569-574
Background
The development of erythropoiesis-stimulating agents (ESAs) with extended serum half-lives has allowed marked prolongation of the administration intervals. The level of oxidative stress is increased in chronic kidney disease, and is reportedly decreased after long-term ESA treatment. However, the effect of different dosing regimens of ESAs on oxidative stress has not been elucidated.Methods
Five-sixths nephrectomized (NX) rats received either 0.4 μg/kg darbepoetin alfa (DA) weekly or 0.8 μg/kg DA fortnightly between weeks 4 and 10. NX animals receiving saline and a sham-operated (SHAM) group served as controls. The levels of oxidized and reduced glutathione (GSSG, GSH) were followed from blood samples drawn fortnightly.Results
During the follow-up, the ratios GSSG/GSH showed similar trends in both DA groups, levels being significantly lower than those in the SHAM group at weeks 8 and 10. GSSG levels were lower than the baseline throughout the study in all groups except for NX controls. The GSH levels were increased in all three NX groups (weeks 6–10) compared with both the baseline and the SHAM groupConclusion
Our results suggest that the extent of oxidative stress is similar in response to different dosing regimens of DA in 5/6 NX rats when comparable hemoglobin levels are maintained. These findings remain to be confirmed in chronic kidney disease patients. 相似文献45.
Attila Nemes Tamás Forster Imre Ungi Viktória Nagy Andrea Vass Attila Pálinkás 《Scandinavian cardiovascular journal : SCJ》2013,47(5):286-292
Objectives. The aim of the present study was to examine the long-term prognostic value of coronary flow velocity reserve (CFR) evaluated by means of stress transoesophageal echocardiography (STEE) in patients who have undergone percutaneous coronary intervention (PCI). Design. The study comprised 31 patients with significant LAD stenosis who underwent LAD-PCI. In consequence of their clinical signs, 11 subjects required rePCI or coronary artery bypass graft (CABG) operation within six months. The clinical status of the remaining 20 cases improved during the follow-up. STEE examinations were performed before LAD-PCI and after it. Results. The CFR of patients in a stable clinical condition improved during the follow-up, while the CFR of those who required rePCI or CABG remained unchanged. From this patient population, two subjects died during the 5-year follow-up. Conclusions. Most of the patients who displayed an improved CFR after PCI suffered no major clinical events during the 5-year follow-up; in contrast, in those who a priori had a low CFR and did not show any improvement after PCI, major events did occur during this period. 相似文献
46.
Dimitra Zannidi Kalliopi Karatzi Eva Karaglani Stavros Liatis Greet Cardon Violeta Iotova Kaloyan Tsochev Nevyana Chakarova Luis A. Moreno Paloma Flores-Barrantes Sándorné Radó Imre Rurik Jaana Lindström Konstantinos Makrilakis Yannis Manios the FeelDiabetes Study Group 《Journal of human nutrition and dietetics》2023,36(1):62-74
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András Komócsi Dániel Aradi Dániel Kehl Imre Ungi Attila Thury Tünde Pintér James J. Di Nicolantonio Adrienn Tornyos András Vorobcsuk 《Archives of Medical Science》2014,10(2):203-212
Introduction
Superior outcomes with transradial (TRPCI) versus transfemoral coronary intervention (TFPCI) in the setting of acute ST-segment elevation myocardial infarction (STEMI) have been suggested by earlier studies. However, this effect was not evident in randomized controlled trials (RCTs), suggesting a possible allocation bias in observational studies. Since important studies with heterogeneous results regarding mortality have been published recently, we aimed to perform an updated review and meta-analysis on the safety and efficacy of TRPCI compared to TFPCI in the setting of STEMI.Material and methods
Electronic databases were searched for relevant studies from January 1993 to November 2012. Outcome parameters of RCTs were pooled with the DerSimonian-Laird random-effects model.Results
Twelve RCTs involving 5,124 patients were identified. According to the pooled analysis, TRPCI was associated with a significant reduction in major bleeding (odds ratio (OR): 0.52 (95% confidence interval (CI) 0.38–0.71, p < 0.0001)). The risk of mortality and major adverse events was significantly lower after TRPCI (OR = 0.58 (95% CI: 0.43–0.79), p = 0.0005 and OR = 0.67 (95% CI: 0.52–0.86), p = 0.002 respectively).Conclusions
Robust data from randomized clinical studies indicate that TRPCI reduces both ischemic and bleeding complications in STEMI. These findings support the preferential use of radial access for primary PCI. 相似文献50.