雷公藤和昆明山海棠植物中挥发性化学成分比较

雷公藤(Tripterygium wilfordii Hook.f.)为卫矛科雷公藤属植物的一种,分布在我国长江以南诸省区。民间早期用其治疗类风湿性关节炎,现已用于多系统疾病的治疗。雷公藤的主要成分包括二萜类、三萜类、倍半萜类和生物碱。近年来,雷公藤的多种药理作用引起广大科研人员的关注,同时,也促进了同属     

京剧器乐的听力损伤（附55例调查报告）

本文对从事京剧打击乐的55人（110耳）进行了听力调查及动态观察。利用图表进行对比分析，发现110耳中高频听力损伤89耳，占81％；语频听力损伤32耳，占29.1%；其中伴有高频耳鸣78耳，占70．9％。动态观察30人（60耳），均为永久性听阈阈移。高频听力损伤最早出现的频率是4kHz，并见典型“V”谷，符合噪声性聋的诊断。     

Der Risikobegriff in Wissenschaft und Gesellschaft

The formal-normative concept of risk in natural and technical sciences is oriented toward effects and damage. A complete understanding of cause and effect relationships is necessary, however, it is normally not available and uncertainties are inadequately taken into account. Risk is distinguished from safety in the formal-normative context. Safety itself can only be understood, however, in relation to uncertainty and therefore to damage. In the legal context, risk is defined by the triad of danger, risk, and residual risk. Risk in the legal context is limited to the domain between danger and residual risk. However, uncertainty has to be considered as distinct from residual risk. In social sciences risk is distinguished from danger. A difference is made between people who decide, i.e., regulators, and those who are affected by the decision. People who decide attribute consequences of the decision and the involvement of risks to their own decision. Concern, however, is grounded in decisions of others, in non-participation, and possible damage is therefore realized as danger and not as risk.     

大鼠延髓腹外侧区在可乐定心血管效应中的作用

目的：探讨大鼠延髓腹外侧区（VLM）在介导可乐定心血管效应中的作用。方法：氨基甲酸乙酯麻醉SD大鼠，应用微量注射和细胞外记录等方法观察尾端延髓腹外侧区（CVLM）和头端延髓腹外侧区（RVLM）内局部给予可乐定导致的心血管活动变化。结果：单侧CVLM微量注射可乐定（5nmol/100nl,n=10)不仅能明显升主动脉血压（AP）和增加心率（HR）（P＜0．01），而且能增加同侧RVLM压力敏感性神经元（n=80)的放电频率（P＜0．01），而单侧RVLM微量注射可乐定（5nmol/100nl,n=9)，明显降低AP和HR（P＜0．01）。结论：RVLM和CVLM在介导可乐定的心血管效应中具有不同的作用。     

Akinetic Mutism and Cognitive-Affective Syndrome Caused by Unilateral PICA Infarction

A 42-year-old man with left posterior inferior cerebellar artery (PICA) infarction presented with akinetic mutism and cognitive impairment. Initially he suffered from akinetic mutism and MRI-documented infarction in the distribution of the left PICA. Twelve days later he developed cognitive impairment. Neuropsychological tests were performed, with the results corrected for age and education being compared with published Korean norms. Impaired performances were evident on executive function testing, with difficulties in planning, abstract reasoning, set-shifting, and perseveration. Akinetic mutism and cognitive-affective syndrome may be a manifestation of unilateral PICA infarction.     

中药抑抗灵治疗抗精子抗体介导的免疫性不育的实验研究Ⅰ

目的 :观察中药抑抗灵对抗精子抗体 (AsAb)介导的免疫性不育的疗效。　方法 :在建立AsAb介导的免疫性不育动物模型的基础上 ,将新西兰兔随机分为 4组 ,即抑抗灵治疗组 ,强的松治疗组 ,未治疗组及阴性对照组。抑抗灵治疗组再随机分为 3组 ,即低剂量组 ,中剂量组和高剂量组。疗程均为 4 5d ,分别在治疗的第 15、30、4 5d检测原血清AsAb呈阳性的雄、雌兔血清AsAb ,计算转阴率 ;检测顺从采精雄兔的精子密度 ,活力 ,活动率及精浆AsAb。　结果 :在抑抗灵治疗的第 15、30、4 5d ,雄、雌兔血清AsAb转阴率低剂量组分别为 30 %、6 0 %、10 0 %和4 4 .4 %、77.8%、10 0 % ;中剂量组分别为 30 %、5 5 .6 %、87.5 %和 4 0 %、6 0 %、10 0 % ;高剂量组分别为 33.3%、6 6 .7%、10 0 %和 4 0 %、6 6 .7%、10 0 %。强的松治疗组雄、雌兔血清AsAb转阴率 15、30、4 5d为 30 %、6 0 %、10 0 %和 30 %、70 %、10 0 %。未经治疗的雄、雌兔AsAb的自然转阴率 15、30、4 5d分别为 0、10 %、2 0 %。经统计 ,未治疗组与抑抗灵 3个剂量组 4 5d比较 ,未治疗组与强的松治疗组 4 5d比较 ,同一剂量抑抗灵治疗 4 5d与 15d血清AsAb转阴率比较差异均有显著性 (P均 <0 .0 5 )。治疗完成后检测顺从采精雄兔精浆AsAb ,经抑抗灵低、中、高剂量治     

Simple Partial Status Epilepticus Localized by Single-Photon Emission Computed Tomography Subtraction in Chronic Cerebral Paragonimiasis

A patient with chronic cerebral paragonimiasis began to have new motor seizures of the right face manifested by clonic contractions that occurred several hundred times a day, consistent with simple partial status epilepticus. Ictal electroencephalogram discharges started from the left frontal region and then spread to the left hemisphere with left frontal maximum. But clinical seizures were limited to the right face. The frequent partial seizures were controlled by the intravenous infusion of phenytoin. Brain magnetic resonance imaging showed multiple conglomerated round nodules with encephalomalacia in the left temporal and occipital lobes. Applying the technique of ictal-interictal single-photo emission computed tomography subtraction, the authors were able to localize the focal ictal-hyperperfusion on left precentral cortex adjacent to the lesions that correspond to the anatomical distribution of left face motor area.     

儿童牙病治疗中医护配合的技巧

儿童牙病要经过诊查-麻醉-牙科处理，要用精密或锐利的器械伸入患儿口腔，所以治疗的前提必须是患儿自觉张口合作。在治疗护理过程中，除了掌握儿童的各年龄阶段的性格特征外，医生、护士的语言交流和操作还需一定的技巧，配合应默契。现对我院250例3岁～12岁患儿治疗及护理配合体会报告如下。