全文获取类型
收费全文 | 210695篇 |
免费 | 3975篇 |
国内免费 | 77篇 |
专业分类
耳鼻咽喉 | 1464篇 |
儿科学 | 7943篇 |
妇产科学 | 3886篇 |
基础医学 | 21001篇 |
口腔科学 | 2407篇 |
临床医学 | 15887篇 |
内科学 | 38109篇 |
皮肤病学 | 1450篇 |
神经病学 | 19959篇 |
特种医学 | 9949篇 |
外国民族医学 | 8篇 |
外科学 | 33631篇 |
综合类 | 2941篇 |
一般理论 | 34篇 |
预防医学 | 21292篇 |
眼科学 | 3558篇 |
药学 | 11727篇 |
中国医学 | 646篇 |
肿瘤学 | 18855篇 |
出版年
2021年 | 451篇 |
2020年 | 316篇 |
2019年 | 545篇 |
2018年 | 22450篇 |
2017年 | 17778篇 |
2016年 | 19938篇 |
2015年 | 1485篇 |
2014年 | 1594篇 |
2013年 | 2142篇 |
2012年 | 8713篇 |
2011年 | 22849篇 |
2010年 | 19806篇 |
2009年 | 12464篇 |
2008年 | 21224篇 |
2007年 | 23493篇 |
2006年 | 2434篇 |
2005年 | 4005篇 |
2004年 | 5136篇 |
2003年 | 5995篇 |
2002年 | 4069篇 |
2001年 | 1081篇 |
2000年 | 1120篇 |
1999年 | 942篇 |
1998年 | 638篇 |
1997年 | 571篇 |
1996年 | 433篇 |
1995年 | 412篇 |
1994年 | 434篇 |
1993年 | 379篇 |
1992年 | 661篇 |
1991年 | 689篇 |
1990年 | 738篇 |
1989年 | 652篇 |
1988年 | 522篇 |
1987年 | 489篇 |
1986年 | 520篇 |
1985年 | 504篇 |
1984年 | 444篇 |
1983年 | 386篇 |
1982年 | 378篇 |
1981年 | 311篇 |
1980年 | 309篇 |
1979年 | 407篇 |
1978年 | 295篇 |
1977年 | 292篇 |
1976年 | 265篇 |
1975年 | 278篇 |
1974年 | 345篇 |
1973年 | 278篇 |
1972年 | 291篇 |
排序方式: 共有10000条查询结果,搜索用时 0 毫秒
21.
22.
23.
Rosendo A. Rodriguez MD PhD Fraser Rubens MD MSc Carlos D. Rodriguez Howard J. Nathan MD 《Journal of neuroimaging》2006,16(2):126-132
OBJECTIVE: The application of intensity thresholds for embolus detection with transcranial Doppler (TCD) can exclude from analysis an unrecognized proportion of high-intensity transient signals (HITS))whose intensities are below the threshold. The lack of consistent threshold criteria between clinical trials may explain part of the discrepancy in the reported HITS counts. We investigated the effect of choosing different thresholds on the sensitivity and specificity of detecting HITS during cardiopulmonary bypass (CPB). METHODS: Two observers independently analyzed TCD recordings from 8 patients under CPB. Doppler signals were classified as true HITS, equivocal HITS, artifacts, and Doppler speckles according to preestablished criteria. The relative intensity of Doppler signals was measured by two different methods (TCD software vs manual). Receiver Operating Characteristic curves determined the optimal threshold for each of the two intensity methods. RESULTS: Reviewers achieved agreement in 96% of 2190 Doppler signals (kappa = 0.90). Relative intensities calculated with the TCD-software method were 3 dB (95% CI: 3.0-3.4) higher than the manual method. The optimal threshold was found at 10 dB (sensitivity: 99%; specificity: 90.8%) with the software method and at 7 dB with the manual method (sensitivity: 96%; specificity: 83%). The use of an intensity threshold 2 dB higher than the optimal increased the rejection of true HITS by 8% and 14%, respectively. CONCLUSIONS: Using intensity thresholds higher than the optimal for embolus detection decreases HITS counts. Choosing a threshold depends on the type of method used for measuring the signal intensity. Uniform threshold criteria and comparative studies between different Doppler devices are necessary for making clinical trials more comparable. 相似文献
24.
25.
26.
Susanne Ramsauer 《Zeitschrift für Psychodrama und Soziometrie》2007,6(2):293-302
Anliegen dieses Artikels ist, die besondere Qualit?t und Chance von Psychodramatischer Supervision zu beschreiben, und gleichzeitig
die Kompatibilit?t und fruchtbare Erg?nzung des Moreno’schen Ansatzes innerhalb des Formats Supervision innerhalb der Sozialen
Arbeit auf zuzeigen. Dies wird anhand von 2 ausgew?hlten Praxisbeispielen dargestellt. Die Handlungskompetenz von Supervisandinnen
und Supervisanden kann durch einfache psychodramatische Interventionen erweitert werden. Handlungshemmung wird überwunden,
Spontaneit?t und Kreativit?t kommen ins Laufen und er?ffnen Perspektiven. 相似文献
27.
28.
Debra L. Roter Richard M. Frankel Judith A. Hall David Sluyter 《Journal of general internal medicine》2006,21(1):28-34
Relationship-centered care reflects both knowing and feeling: the knowledge that physician and patient bring from their respective domains of expertise, and the physician’s and patient’s experience, expression, and perception of emotions during the medical encounter. These processes are conveyed and reciprocated in the care process through verbal and nonverbal communication. We suggest that the emotional context of care is especially related to nonverbal communication and that emotion-related communication skills, including sending and receiving nonverbal messages and emotional self-awareness, are critical elements of high-quality care. Although nonverbal behavior has received far less study than other care processes, the current review argues that it holds significance for the therapeutic relationship and influences important outcomes including satisfaction, adherence, and clinical outcomes of care. 相似文献
29.
Rammurti T Kamble George B Selby Martha Mims Mohamed A Kharfan-Dabaja Howard Ozer James N George 《Biology of blood and marrow transplantation》2006,12(5):506-510
Iron overload presenting as exacerbation of hepatic graft-versus-host disease (GVHD) after allogeneic hematopoietic stem cell transplantation has not been previously described. We report 6 patients with established hepatic GVHD in whom iron overload (median serum ferritin, 7231 mug/dL; median transferrin saturation, 77%) resulting from a lifetime median of 20 units of packed red blood cell transfusions was manifested by worsening of liver function. Liver biopsies performed in 4 patients confirmed severe iron overload and also hepatic GVHD. Analysis for the C282Y and H63D hemochromatosis gene mutation was negative for the homozygous state in all 6 patients. Erythropoietin-assisted phlebotomy resulted in normalization of liver function at a median of 7 months and of serum ferritin at a median of 11 months. Immunosuppressive therapy was successfully tapered in all 4 patients who completed the phlebotomy program, and this supported the impression that iron overload, rather than GVHD, was the principal cause of liver dysfunction. At a median follow-up of 50 months (range, 18-76 months) from the transplantation and 25 months (range, 5-36 months) from ferritin normalization, all 4 patients require maintenance phlebotomy. We conclude that iron overload can mimic GVHD exacerbation, thus resulting in unnecessary continuation or intensification of immunosuppressive therapy for GVHD, and that maintenance phlebotomy is necessary after successful iron-reduction therapy. 相似文献
30.
Dr. Arthur A. Dunk MRCP Natasha Kyprianou MSc Peter Davies PhD Howard C. Thomas PhD FRCP 《Digestive diseases and sciences》1988,33(4):472-476
Castrated or sham-operated male athymic mice were inoculated with cells from the human hepatocellular carcinoma cell line PLC/PRF/5. There were no significant differences between the two groups with respect to the number of animals developing tumors, the time to tumor development, or the subsequent rate of increase in either tumor base area or mouse serum alpha-fetoprotein concentration. Androgen receptors were assayed in nuclei obtained from three separate liver cancer cell lines and from normal adult human liver. Similar concentrations, ranging from 235 to 550 fmol/mg DNA, of nuclear androgen receptors were detected in all tissues. Low percentages of androgen receptors were retained on DNA-cellulose. Although the presence of receptors implies the potential for metabolic effects of androgens in normal and malignant liver, our in vivostudies suggest that castration does not alter significantly the growth of liver cancer xenografts in athymic mice. 相似文献