全文获取类型
收费全文 | 1276725篇 |
免费 | 99758篇 |
国内免费 | 1987篇 |
专业分类
耳鼻咽喉 | 18423篇 |
儿科学 | 44349篇 |
妇产科学 | 35008篇 |
基础医学 | 182164篇 |
口腔科学 | 33581篇 |
临床医学 | 111244篇 |
内科学 | 258208篇 |
皮肤病学 | 28020篇 |
神经病学 | 100356篇 |
特种医学 | 51198篇 |
外国民族医学 | 660篇 |
外科学 | 196380篇 |
综合类 | 27048篇 |
现状与发展 | 1篇 |
一般理论 | 377篇 |
预防医学 | 95714篇 |
眼科学 | 27912篇 |
药学 | 94764篇 |
2篇 | |
中国医学 | 2422篇 |
肿瘤学 | 70639篇 |
出版年
2018年 | 13131篇 |
2017年 | 9963篇 |
2016年 | 10899篇 |
2015年 | 12369篇 |
2014年 | 17162篇 |
2013年 | 26209篇 |
2012年 | 36016篇 |
2011年 | 38050篇 |
2010年 | 22800篇 |
2009年 | 21806篇 |
2008年 | 36634篇 |
2007年 | 39245篇 |
2006年 | 39499篇 |
2005年 | 38437篇 |
2004年 | 37592篇 |
2003年 | 36444篇 |
2002年 | 35795篇 |
2001年 | 63987篇 |
2000年 | 66497篇 |
1999年 | 56407篇 |
1998年 | 15128篇 |
1997年 | 13753篇 |
1996年 | 14195篇 |
1995年 | 13452篇 |
1994年 | 12765篇 |
1993年 | 11790篇 |
1992年 | 44554篇 |
1991年 | 43464篇 |
1990年 | 42216篇 |
1989年 | 40111篇 |
1988年 | 36894篇 |
1987年 | 36234篇 |
1986年 | 33618篇 |
1985年 | 32278篇 |
1984年 | 24136篇 |
1983年 | 20268篇 |
1982年 | 11723篇 |
1981年 | 10691篇 |
1980年 | 9515篇 |
1979年 | 21341篇 |
1978年 | 14821篇 |
1977年 | 12532篇 |
1976年 | 11693篇 |
1975年 | 12623篇 |
1974年 | 14661篇 |
1973年 | 14117篇 |
1972年 | 12944篇 |
1971年 | 11729篇 |
1970年 | 11050篇 |
1969年 | 10024篇 |
排序方式: 共有10000条查询结果,搜索用时 19 毫秒
941.
J. E. Hammond R. G. Berger T. S. Carey R. Rutledge T. J. Cleveland J. P. Kichak C. F. Ayscue 《Journal of medical systems》1991,15(3):257-267
Many hospitals today have implemented widely disparate information systems on mainframe and mini-computer hardware. The advent of network technology in hospitals has made it possible to access information in these systems. Unfortunately, the user interfaces to applications on these systems are unique and difficult to learn, which makes them unsuitable for use by clinical services. In this paper we describe the development of a Physician's Workstation which integrates information from multiple existing information systems and discuss how the workstation makes it possible to move from the departmental systems of the present to the computer-based medical record system of the future. 相似文献
942.
Complications associated with central venous catheters inserted in critically ill neonates 总被引:2,自引:0,他引:2
V Hruszkewycz P C Holtrop D G Batton R S Morden P Gibson J D Band 《Infection control and hospital epidemiology》1991,12(9):544-548
OBJECTIVE: To assess the incidence and spectrum of complications associated with central venous catheter (CVC) placement in the critically ill infant. DESIGN: A prospective study of all babies hospitalized in a neonatal intensive care unit (NICU) from January 1989 to December 1989. Potential risk factors associated with infection were evaluated by a case-control comparison. SETTING: Conducted at a university-affiliated, tertiary care community hospital. PATIENTS: Neonates requiring intensive care and a central venous catheter. Controls consisted of noninfected babies. RESULTS: Of 263 critically ill neonates, only 13 (4.9%) required a CVC insertion. Seventeen CVCs were placed in these 13 neonates for a total duration of 600 days (median, 32 days/cannula). Fifteen (88%) of these cannulas had one or more complications during its catheter life including dislodgement or leakage (53%), occlusion or thrombosis (47%), infections (29%), or minor bleeding (12%). Five babies (29%) developed 6 episodes of bloodstream infection including 3 sporadic cases due to Staphylococcus epidermidis and a cluster of fungemia due to Malassezia furfur associated with lipid emulsion therapy. Infants with a CVC-associated infection were a younger gestational age (24 weeks versus 32 weeks, p = .04) and weighed less at birth (580 g versus 1285 g, p = .02). The overall rate of bloodstream infection was one episode per 100 days of catheter use. CONCLUSIONS: CVCs may be lifesaving to a critically ill neonate, but complications occur frequently. Use must be restricted to infants in whom alternate delivery routes of intravenous therapy or support are otherwise unavailable. 相似文献
943.
D P Taggart D C McMillan T Preston R Richardson A Shenkin H J Burns D J Wheatley 《Nutrition (Burbank, Los Angeles County, Calif.)》1991,7(4):271-274
Total energy expenditure (TEE) was measured by doubly labeled water in 13 preoperative patients undergoing elective coronary artery surgery and compared to resting energy expenditure (REE) measured by indirect calorimetry (IC) calculated from the Harris-Benedict (HB) formula or from formulas based on midarm circumference and arm muscle circumference. Mean REE measured by IC and calculated from the HB, midarm circumference, arm muscle circumference formulas were 62, 75, 62, and 69%, respectively, of TEE measured by doubly labeled water. REE measured by IC correlated significantly with that predicted by the HB (p = 0.006) but not the anthropometric formulas. The relationship between REE derived from anthropometric predictive formulas and REE measured by IC is altered in ischemic heart disease. 相似文献
944.
U Caliceti A Rinaldi Ceroni G Lisignoli P Chieco O Cavicchi 《Archives of oto-rhino-laryngology》1989,246(5):365-367
A microfluorometric method was used to determine the nuclear DNA content in the nasopharyngeal carcinomas (NPC) of 25 patients treated before 1983. Eleven patients are still alive with no evidence of disease (NED), while the rest died of their disease (DOD). All of the patients received a cycle of radiotherapy, while some also received chemotherapy or neck dissections. The neoplastic cells studied were taken from the original biopsy blocks, deparaffinized, isolated by enzymatic treatment and mechanical fragmentation, and then Feulgen-stained. The cytofluorometric measurement was carried out by a microphotometer equipped for fluorescence excitation and connected to a computer. This method allowed us to construct a histogram of the DNA content in the neoplastic cells. Different neoplastic classes were identified and represent the heteroclonality of the tumor, which can be expressed by the heteroclonality index (HCT). From the collected data it appears that the NED patients all had a low HTC (less than 1) and only 7 of the DOD patients had low HTCs (less than 1). Six of the DOD patients with a low HTC were in advanced stages of their tumor at the time of diagnosis, while the remaining patient did not complete his treatment. Our results show that the DNA analysis of the NPC cell population may offer a useful tool in predicting the biological behavior of this tumor and also improving its treatment. 相似文献
945.
Twenty two patients (age range: 1 month to 11 years) were treated for congenital diaphragmatic defects (excluding hiatus hernia) in the six year period 1983-8. Presenting features were failure to thrive (n = 7), abdominal pain and vomiting (n = 4), chronic respiratory symptoms (n = 3), and inability to wean from ventilatory support (n = 3). The defect was an incidental finding in five patients. Operative repair was performed with no mortality or serious postoperative morbidity. Dramatic improvement occurred in 15 of the 17 symptomatic patients. Awareness of the differential diagnosis should avoid delay in diagnosis or inappropriate treatment. Surgical correction is strongly recommended in all cases. 相似文献
946.
The question of the necessity of in-patient facilities of the area of (child and) adolescent neuropsychiatry is to be discussed further. The extremely optimistic views on this question of approximately 20 years ago cannot be maintained for the examined area and the examination time. In the LNKH Valduna/Vorarlberg, an establishment that was intended exclusively for adults until 1987, from 1980-1984 (evaluated in detail) and from 1984-1987 a further 60 minors were admitted. The exact evaluation shows that the conspicuousnesses of behaviour of a main group was so clear each time that it could not be treated elsewhere and certainly not in outpatient facilities. In the examined group the amount of patients with behaviour and socialization disorders outweighed by far the psychoses, also a high percentage of patients was multi morbid and/or had multiple handicaps. The resulting conclusion seems to us to be the necessity of setting-up a specific in-patients treatment unit for this group of patients with sufficient infrastructure. 相似文献
947.
948.
Ethmoidal mucocoeles in children 总被引:1,自引:0,他引:1
Children presenting with ethmoidal mucocoeles are rare. Five children are presented with such findings, and the diagnosis, treatment and possible aetiology discussed. C.T. scanning was found to be the investigation of choice, while plain sinus X-rays correlated poorly with the presence of disease. Exenteration through an external approach was found to be satisfactory. In two cases drainage obstruction due to congenital abnormality was thought to be the underlying cause, while in four cases there was a strong history of atopy, indicating allergy as a possible reason for mucocoele formation. 相似文献
949.
950.
This paper suggests that like ethanol, methanol also produces certain changes in the steady state level of monoamines in hypothalamus and striatum of albino rats. Though, the toxic manifestations of methanol are attributed to the metabolic end product of methanol viz. formic acid by several workers, we report here that the methanol-induced brain monoamine changes, at least, could be attributed to the direct action of methanol rather than to its metabolic end products like formaldehyde or formate. Studies in the steady state level of rat brain monoamines have shown that after methanol administration (3 g/kg), there is severe depletion of dopamine level in striatum but a significant increase in the level of dopamine, serotonin and 5-hydroxy indole acetic acid in hypothalamus. At the same time, norepinephrine and epinephrine levels are reduced in hypothalamus as well as in striatum. These effects do not seem to be induced by metabolic acidosis. The changes in monoamine levels are very well correlated with the blood and brain level of methanol as evidenced by maintaining a higher methanol level either by simultaneous administration of ethanol or by blocking methanol metabolism by pretreatment with 4-methyl pyrazole and 3-amino-1,2,4-triazole. It is thus postulated that monoamine changes induced by methanol appear to be the direct effect of methanol per se on the monoaminergic neuronal membranes. 相似文献