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101.
圆孔外面的观察和测量及其面积的回归方程 总被引:4,自引:0,他引:4
60具成人颅骨颅底外面的圆孔观察和测量结果表明:圆孔多呈圆形,其次是卵圆形,其它形较少见.据圆孔与翼突外侧板根部延长线的位置关系,分圆孔位置为三型.圆孔外面观的各项测值左右间均无统计学差异,但其中管性圆孔管长度个体差异较大.圆孔的面积左右比较对称者占3.33±2.34%,左>右者占65.51±6.30%,右>左者占34.48±6.30%.圆孔面积左右对称性比较,对临床诊断疾病有参考意义.其面积的回归方程可由其长、宽径乘积推算 . 相似文献
102.
Sergei N. Magonov Deyuan Shen Renyuan Qian 《Macromolecular chemistry and physics.》1989,190(10):2563-2570
Fourier transform infra-red (IR) studies on samples of atactic polystyrene with different thermal history, i.e. quenched from the melt (QM), quenched from the rubbery state (QR), slowly cooled (SC), and sub-glass-transition (sub-Tg) annealed (AN), were carried out in the absorption region from 500 to 600 cm?1 with gradually increasing temperatures through the glass transition region at 100°C. The heights of the positive peak (532 cm?1) and the negative peak (566 cm?1) appearing in the temperature difference spectra, T-60°C, are considered to be a measure of the amount of frequency shifts for the 540 cm?1 and 557 cm?1 bands in the conformationally sensitive spectral range of atactic polystyrene. These bands show a continuously increasing low-frequency shift with increasing temperature, except for sample QM, the 557 cm?1 band of which shows an inappreciable frequency shift in the range 60 < T/°C < 100. The different temperature behaviour of these shifts for samples QM, QR, SC and AN is due to changes in their intermolecular interactions. Sub-Tg annealing of the sample QM is shown to shift the frozen high-temperature state of the quenched sample to the temperature-defined equilibrium. For all samples of different thermal history the difference in their IR spectra vanish at temperatures above Tg. 相似文献
103.
系统观察57例健康人口服灵芝(灵芝多糖体55mg/片)前后甲襞微循环的变化。结果显示:服药前后大、小动脉血压无显著变化;口服灵芝3天后输入枝口径及输出枝口径均有明显扩张;管袢密度、红细胞流速增加不显著。口服灵芝7天的动态变化显示,服药8h后输入枝、输出枝口径即有显著扩张,第7天管袢密度开始明显增加。服用不同剂量灵芝(2片、4片、8片,3次/日)3h后,管袢密度、输入枝、输出枝口径、流速均有增加趋向,但P>0.05,其中8片组管袢口径、管袢密度有显著增加(P<0.05),但红细胞流速却有显著下降(P<0.05)。结果提示:连续、适量(2片,3次~4次/日)服用灵芝,可显著改善微循环灌流量,从而改善和保护组织及脏器功能。 相似文献
104.
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107.
Requirements for the development of IL-4-producing T cells during intestinal nematode infections: what it takes to make a Th2 cell in vivo 总被引:1,自引:0,他引:1
Zhugong Liu Qian Liu John Pesce Robert M. Anthony Erika Lamb Jeannette Whitmire Hossein Hamed Motoko Morimoto Joseph F. Urban Jr William C. Gause 《Immunological reviews》2004,201(1):57-74
Summary: Components of the type 2 immune response may mediate host protection against both helminthic parasites and harmful allergic responses. A central player in this response is the T‐helper 2 (Th2) effector cell, which produces interleukin (IL)‐4, IL‐5, IL‐13, and other Th2 cytokines during the primary and memory response. Specific aspects of the parasite that trigger Th2‐cell differentiation are not yet defined. Furthermore, the cell types and cell surface and secreted molecules that provide the immune milieu required for the development of Th2 effector cells and also Th2 memory cells are not well understood. They will probably vary with the particular helminth or other antigen inducing the Th2 response. We have used third stage larvae of intestinal nematode parasites as adjuvants to promote naïve nonparasite antigen‐specific T cells to differentiate into Th2 cells. This model system avoids possible parasite antigen‐specific T‐cell clones or cross‐reactive memory T cells that may preferentially differentiate into Th2 effector cells during the course of infection and confound the stereotypical components of parasite‐induced Th2 cell differentiation. We have found that these parasites have a potent adjuvant effect and have used our model system to begin to investigate the events that lead to the development of polarized Th2 cells in vivo. 相似文献
108.
IMPT1, an imprinted gene similar to polyspecific transporter and multi- drug resistance genes 总被引:5,自引:1,他引:5
Dao D; Frank D; Qian N; O'Keefe D; Vosatka RJ; Walsh CP; Tycko B 《Human molecular genetics》1998,7(4):597-608
Human chromosome 11p15.5 and distal mouse chromosome 7 include a
megabase-scale chromosomal domain with multiple genes subject to parental
imprinting. Here we describe mouse and human versions of a novel imprinted
gene, IMPT1 , which lies between IPL and p57 KIP2 and which encodes a
predicted multi-membrane-spanning protein similar to bacterial and
eukaryotic polyspecific metabolite transporter and multi- drug resistance
pumps. Mouse Impt1 and human IMPT1 mRNAs are highly expressed in tissues
with metabolite transport functions, including liver, kidney, intestine,
extra-embryonic membranes and placenta, and there is strongly preferential
expression of the maternal allele in various mouse tissues at fetal stages.
In post-natal tissues there is persistent expression, but the allelic bias
attenuates. An allelic expression bias is also observed in human fetal and
post-natal tissues, but there is significant interindividual variation and
rare somatic allele switching. The fact that Impt1 is relatively repressed
on the paternal allele, together with data from other imprinted genes,
allows a statistical conclusion that the primary effect of human chromosome
11p15.5/mouse distal chromosome 7 imprinting is domain-wide relative
repression of genes on the paternal homolog. Dosage regulation of the
metabolite transporter gene(s) by imprinting might regulate placental and
fetal growth.
相似文献
109.
中国人群DXS102座位多态性鉴定及其应用 总被引:13,自引:0,他引:13
目的探讨中国人群中DXS102座位的多态分布。方法应用PCR扩增片段长度多态性(Amp-FLP)研究了无亲缘关系的234条X染色体。结果DXS102座位等位片段有8个,核心单元AC二核苷酸重复数为13~21,频率分布在0.013~0.156之间,杂合度观察值和无偏估测值分别为0.87和0.80,多态信息含量(PIC)0.80,女性基因型数为22个,男性基因型数为8个,该座位多态分布符合Hardy-Weinberg平衡定律。DXS102座位在中国人群和欧洲人群的分布有明显的种族差异,在中国人群中发现了两个新的等位片段。应用DXS102座位的短串联重复序列多态性对一接受基因治疗的血友病B家系进行分析和携带者筛查。结论DXS102座位连锁分析有望成为一种有效的血友病B基因诊断的方法。 相似文献
110.