Strengthening human resources for health through multisectoral approaches and leadership: the case of Cameroon

Problem

Cameroon has a severe shortage of human resources for health (HRH) and those that are available are concentrated in urban areas.

Approach

As the result of a national emergency plan for the years 2006–2008, innovative strategies and a multisectoral partnership – led by the Ministry of Public Health and supported by diverse national and international organizations – were developed to address the shortages and maldistribution of HRH in Cameroon.

Local setting

At the time that the emergency plan was developed, Cameroon had health services of poor quality, an imbalance between HRH training and employment, a maldistribution of HRH between urban and rural areas and a poor allocation of financial resources for HRH. It also lacked an accreditation system for use in the training of health workers.

Relevant changes

Between 2007 and 2009, the number of active health workers in Cameroon increased by 36%, several new institutions for higher education in health care and training schools for paramedical staff and midwives were opened, and a national strategy for universal health coverage was developed.

Lessons learnt

In the improvement of HRH, strong leadership is needed to ensure effective coordination and communication between the many different stakeholders. A national process of coordination and facilitation can produce a consensus-based view of the main HRH challenges. Once these challenges have been identified, the stakeholders can plan appropriate interventions that are coordinated, evidence-based and coherent.     

Mental health interventions by lay counsellors: a systematic review and meta-analysis

ObjectiveTo investigate the effectiveness of community-based mental health interventions by professionally trained, lay counsellors in low- and middle-income countries.MethodsWe searched PubMed®, Cochrane Central Register of Controlled Trials, PROSPERO and EBSCO databases and professional section publications of the United States National Center for PTSD for randomized controlled trials of mental health interventions by professionally trained, lay counsellors in low- and middle-income countries published between 2000 and 2019. Studies of interventions by professional mental health workers, medical professionals or community health workers were excluded because there are shortages of these personnel in the study countries. Additional data were obtained from study authors. The primary outcomes were measures of post-traumatic stress disorder, depression, anxiety and alcohol use. To estimate effect size, we used a random-effects meta-analysis model.FindingsWe identified 1072 studies, of which 19 (involving 20 trials and 5612 participants in total) met the inclusion criteria. Hedges'' g for the aggregate effect size of the interventions by professionally trained, lay counsellors compared with mostly either no intervention or usual care was −0.616 (95% confidence interval: −0.866 to −0.366). This result indicates a significant, medium-sized effect. There was no evidence of publication bias or any other form of bias across the studies and there were no extreme outliers among the study results.ConclusionThe use of professionally trained, lay counsellors to provide mental health interventions in low- and middle-income countries was associated with significant improvements in mental health symptoms across a range of settings.     

Medical Negligence - Going Dutch

Forensic DNA profiling combines the dynamic science of molecular genetics with the complexities of the forensic context. As such, throughout its twenty-year history, this field has seen continuous change, remarkable growth and an associated level of public, legal and scientific scrutiny previously unknown in the forensic sciences. Almost ubiquitously, applications of forensic DNA profiling have focused on resolving the identity of the donor of a particular sample of biological evidence. This is typically achieved by targeting non-coding microsatellite (or STR) loci. Recently however, novel techniques have emerged that target different DNA polymorphisms and allow scientists to address additional questions about the evidence, beyond the identification of source. In this short review we introduce an example of this next generation of forensic DNA techniques, single nucleotide polymorphisms (or SNPs). We summarise their molecular and technological basis and the manner in which they may be applied to further advance the capabilities of forensic investigators.     

Recurrent herpes labialis during isotretinoin therapy: is there a role for photosensitivity?

Isotretinoin (13-cis-retinoic acid) is one of the synthetic retinoids derived from vitamin A. Vitamin A derivatives demonstrate virucidal activity, both in vivo and in vitro. Isotretinoin has been used for the treatment of recurrent herpes simplex with encouraging results. However, we present a case with frequent attacks of herpes labialis during isotretinoin therapy for acne, who had a marked decrease in frequency of recurrences following strict use of sunscreens.     

功能神经影像学——语言功能的脑磁图研究

脑磁图是近10年开始应用于功能神经影像学研究的，又被称为磁源成像，是利用超导技术制成的高敏感传感器可以在颅外及时探测大脑神经元的电活动所产生的磁场，并且把所探测到的磁源重叠到相应的MRI图像上从而确定磁源的位置。它不受组织导电率的影响，且具有极高的时间分辨率。研究表明，脑磁图在语言功能的定侧定位方面的研究是可行的、可信的，并且具有可重复性。此外，脑磁图在阅读困难症的病因研究和疗效观察方面也具有重要意义。     

Effect of central hypothyroidism on Doppler-derived myocardial performance index.

BACKGROUND: Myocardial performance index (MPI) has been used to assess global ventricular function in different types of cardiac disease. Thyroid hormones influence cardiac performance directly and indirectly by changes in peripheral circulation. The aim of this study was to evaluate the possible effect of central hypothyroidism (CH) on MPI. METHODS: The study included 28 control subjects and 7 patients with CH without cardiac disease. MPI was defined as the sum of isovolumetric contraction time (ICT) and isovolumetric relaxation time divided by ejection time. Patients were submitted to hormonal therapy with thyroxin and the study was repeated after 35 to 42 days. RESULTS: MPI was significantly higher in patients with CH (0.54 +/- 0.08) than in control subjects (0.40 +/- 0.05) (P =.002). The increase in MPI was caused by the prolongation of ICT without a significant variation of isovolumetric relaxation time and ejection time. After hormonal therapy there was a significant reduction of MPI (0.54 +/- 0.08 vs 0.42 +/- 0.07; P =.028) and ICT. CONCLUSION: MPI was increased in patients with untreated CH. The increase was related to prolongation of ICT and reverted by hormonal therapy.