全文获取类型
收费全文 | 161206篇 |
免费 | 10725篇 |
国内免费 | 1212篇 |
专业分类
耳鼻咽喉 | 2255篇 |
儿科学 | 3025篇 |
妇产科学 | 3744篇 |
基础医学 | 24079篇 |
口腔科学 | 3342篇 |
临床医学 | 15264篇 |
内科学 | 30797篇 |
皮肤病学 | 4345篇 |
神经病学 | 12068篇 |
特种医学 | 8088篇 |
外科学 | 21895篇 |
综合类 | 2158篇 |
现状与发展 | 5篇 |
一般理论 | 81篇 |
预防医学 | 9724篇 |
眼科学 | 4316篇 |
药学 | 13678篇 |
中国医学 | 1597篇 |
肿瘤学 | 12682篇 |
出版年
2023年 | 985篇 |
2022年 | 2739篇 |
2021年 | 4831篇 |
2020年 | 2465篇 |
2019年 | 3588篇 |
2018年 | 4410篇 |
2017年 | 3235篇 |
2016年 | 4187篇 |
2015年 | 5637篇 |
2014年 | 6916篇 |
2013年 | 8375篇 |
2012年 | 12654篇 |
2011年 | 12293篇 |
2010年 | 7253篇 |
2009年 | 6069篇 |
2008年 | 9262篇 |
2007年 | 9126篇 |
2006年 | 8380篇 |
2005年 | 7986篇 |
2004年 | 7132篇 |
2003年 | 6192篇 |
2002年 | 5380篇 |
2001年 | 4392篇 |
2000年 | 4041篇 |
1999年 | 3273篇 |
1998年 | 1312篇 |
1997年 | 989篇 |
1996年 | 953篇 |
1995年 | 864篇 |
1994年 | 756篇 |
1993年 | 644篇 |
1992年 | 1583篇 |
1991年 | 1575篇 |
1990年 | 1360篇 |
1989年 | 1242篇 |
1988年 | 1156篇 |
1987年 | 1032篇 |
1986年 | 1012篇 |
1985年 | 885篇 |
1984年 | 645篇 |
1983年 | 566篇 |
1982年 | 399篇 |
1981年 | 377篇 |
1980年 | 339篇 |
1979年 | 522篇 |
1978年 | 407篇 |
1977年 | 388篇 |
1976年 | 343篇 |
1974年 | 359篇 |
1973年 | 329篇 |
排序方式: 共有10000条查询结果,搜索用时 16 毫秒
141.
142.
143.
The authors compared children (ages 7-13 years) of unipolar depressed mothers with children of nondepressed psychiatric patients, of nondepressed medical patients, and of nondepressed mothers in the community. The children's adjustment was rated by clinicians on the Child Adjustment Schedule and by the mothers on the Child Behavior Checklist. The highest proportion of clinically significant problems was found in the children of the depressed mothers. However, the overlap between the problems of these children and those of the children of the nondepressed psychiatric patients calls into question the formulation that children's adjustment difficulties are specific to parental depression. 相似文献
144.
Glucocorticoid effects on kainic acid-induced motor seizures and wet dog shakes in rats were investigated by adrenalectomy and dexamethasone treatment. One-day adrenalectomy attenuated kainic acid-induced wet dog shakes and seizure activity. These effects were restored by dexamethasone. Administration of dexamethasone to non-adrenalectomized rats potentiated kainic acid-induced wet dog shakes and severity of seizure activity. These results suggest that glucocorticoids may play an important role in modulating the severity of kainic acid-induced seizures and wet dog shakes. 相似文献
145.
146.
147.
A M S El-Eragi M E Hamid N S Saeed A H Ahmed K Lee Y-H Kook M M Mukhtar 《The international journal of tuberculosis and lung disease》2007,11(6):671-675
OBJECTIVES: To characterise mycobacterial clinical isolates based on amplification of the rpoB gene. SETTING: One hundred and thirty-five mycobacterial isolates cultured from suspected pulmonary tuberculosis (TB) patients were identified phenotypically. Molecular characterisation of the isolates was performed based on amplification of the rpoB gene, using duplex polymerase chain reaction (DPCR), PCR-restriction fragment length polymorphism (RFLP) and nested PCR-based sequence analysis techniques. RESULTS: The DPCR assay identified 129 of 135 (95.5%) clinical isolates as Mycobacterium tuberculosis complex species. Restriction enzyme analysis of the rpoB PCR product using Hind II identified 134 of the 135 (99.3%) isolates as M. tuberculosis complex, while nested PCR sequence analysis of the rpoB gene identified 133/133 examined isolates (100%) as M. tuberculosis species. No mycobacteria other than M. tuberculosis (MOTT) were detected among the studied isolates. CONCLUSION: DPCR, PCR/RFLP Hind II and nested PCR sequence analysis of the rpoB gene techniques showed comparable efficiency in the characterisation of Mycobacterium isolates. Nested PCR sequence analysis of the rpoB gene was superior to PCR/RFLP for characterisation of suspected M. tuberculosis isolates, while the DPCR technique showed less sensitivity. As PCR-RFLP requires less sophisticated laboratory facilities than nested PCR sequence analysis, it would be more appropriate to be adopted for accurate characterisation of mycobacteria in countries with a weak infrastructure. 相似文献
148.
J-H Lee S-Y Kwon H-I Yoon C J Yoon K-W Lee S-G Kang C-T Lee 《The international journal of tuberculosis and lung disease》2007,11(7):781-787
OBJECTIVE: To evaluate the factors that influence the outcome of bronchial arterial embolisation (BAE) in chronic tuberculosis (TB). In cases of chronic TB, non-bronchial systemic arteries (NBSA) provide a significant source of massive or recurrent haemoptysis. DESIGN: Medical records and radiological findings of 30 consecutive TB patients who underwent BAE were retrospectively analysed and compared with those of 19 bronchiectasis patients. RESULTS: Chronic TB patients had higher numbers of total feeding vessels (4.40 +/- 3.85 vs. 1.79 +/- 1.51, P = 0.007) and NBSA (1.57 +/- 1.63 vs. 0.42 +/- 0.61, P = 0.005) than the bronchiectasis patients. The number of embolisations required for obliterating feeding vessels (3.87 +/- 2.48 vs. 1.95 +/- 1.47, P = 0.004), and the incidence of incomplete embolisation (30% vs. 5.3%, P = 0.033) were also higher in the TB patients. Moreover, recurrence after BAE was more frequent in the TB patients (17/30, 56.7% vs. 5/19, 26.3%, P = 0.037). Male sex, past history of haemoptysis and incomplete embolisation during BAE were associated with higher recurrence of haemoptysis in chronic TB patients. The existence of a fungus ball or significant pleural thickening (>/=10 mm) was not found to influence the recurrence rate of haemoptysis. CONCLUSION: The haemoptysis recurrence rate was higher in chronic TB than in bronchiectasis; this was found to be related to incomplete feeding vessel embolisation. 相似文献
149.
Kai-Hang Yiu MBBS Chung-Wah Siu MBBS Chu-Pak Lau MD Kathy L.F. Lee MBBS Hung-Fat Tse MD 《Heart rhythm》2007,4(2):221-223
We report a case of successful transvenous, catheter-based, cavotricuspid isthmus ablation for treatment of atrial flutter using microwave energy. Microwave energy was delivered at 900–930 MHz using 21 W of power. Bidirectional cavotricuspid isthmus conduction block was achieved by microwave ablation without any patient discomfort or complication during the procedure. Our initial experience suggests that transcatheter microwave ablation is feasible for the cure of typical atrial flutter. 相似文献
150.
Hoon-Chul Kang Ji Won Kwon Young Mock Lee Heung Dong Kim Hong Jin Lee Si Houn Hahn 《Child's nervous system》2007,23(11):1301-1307
OBJECTIVES: This study sought to characterize epileptic phenotypes in children with nonspecific mitochondrial disease (MD) and to evaluate MD diagnostic approaches. METHODS: A retrospective analysis of the medical, electroencephalogram, and laboratory records of 142 patients with epilepsy was performed. The patients were evaluated for MD, and 124 patients were included in the final cohort. The MD criteria used included an oral glucose lactate stimulation test (OGLST) and urine organic acid/plasma amino acid (UOA/PAA) assays as metabolic indicators of modified Walker criteria, as suggested by Bernier et al. (Neurology 59:1406-1411, 2002). RESULTS: Twenty-two patients were classified as having definite MD (9), probable MD (5), possible MD (6), or pyruvate dehydrogenase (PDH) deficiency (3), including one patient which showed a respiratory chain (RC) defect and PDH deficiency. Seven out of eight patients in whom significant RC defects were observed showed complex I defects. In 14 patients, epileptic seizures start at infantile ages. Of 17 patients who substantially presented generalized seizures, 4 patients started with partial seizures. Five patients consistently presented only partial seizures. The OGLST and UOA/PAA assays were useful for a more precise diagnosis of MD, although low positive predictive value of the OGLST was regrettable. No patient was classified as definite MD by Walker's original criteria, but the use of our revised MD criteria resulted in the classification of nine additional patients as definite MD. CONCLUSIONS: MD manifested considerable diverse epileptic phenotypes and should be considered in the differential diagnosis of epilepsy in children with unexplained encephalomyopathy and progressive and fluctuating clinical courses. 相似文献