全文获取类型
收费全文 | 26347篇 |
免费 | 1287篇 |
国内免费 | 251篇 |
专业分类
耳鼻咽喉 | 213篇 |
儿科学 | 513篇 |
妇产科学 | 620篇 |
基础医学 | 2768篇 |
口腔科学 | 524篇 |
临床医学 | 2288篇 |
内科学 | 7681篇 |
皮肤病学 | 565篇 |
神经病学 | 2316篇 |
特种医学 | 916篇 |
外科学 | 4298篇 |
综合类 | 62篇 |
一般理论 | 5篇 |
预防医学 | 951篇 |
眼科学 | 346篇 |
药学 | 1373篇 |
中国医学 | 43篇 |
肿瘤学 | 2403篇 |
出版年
2024年 | 27篇 |
2023年 | 224篇 |
2022年 | 460篇 |
2021年 | 773篇 |
2020年 | 486篇 |
2019年 | 641篇 |
2018年 | 763篇 |
2017年 | 586篇 |
2016年 | 722篇 |
2015年 | 784篇 |
2014年 | 998篇 |
2013年 | 1372篇 |
2012年 | 2119篇 |
2011年 | 2078篇 |
2010年 | 1220篇 |
2009年 | 1093篇 |
2008年 | 1906篇 |
2007年 | 1802篇 |
2006年 | 1648篇 |
2005年 | 1662篇 |
2004年 | 1520篇 |
2003年 | 1345篇 |
2002年 | 1241篇 |
2001年 | 157篇 |
2000年 | 110篇 |
1999年 | 161篇 |
1998年 | 219篇 |
1997年 | 202篇 |
1996年 | 154篇 |
1995年 | 183篇 |
1994年 | 149篇 |
1993年 | 139篇 |
1992年 | 87篇 |
1991年 | 74篇 |
1990年 | 87篇 |
1989年 | 52篇 |
1988年 | 46篇 |
1987年 | 38篇 |
1986年 | 49篇 |
1985年 | 51篇 |
1984年 | 56篇 |
1983年 | 41篇 |
1982年 | 53篇 |
1981年 | 32篇 |
1980年 | 43篇 |
1979年 | 25篇 |
1978年 | 15篇 |
1977年 | 17篇 |
1975年 | 19篇 |
1974年 | 20篇 |
排序方式: 共有10000条查询结果,搜索用时 15 毫秒
71.
Giuseppe Giuffre’ Vincenzo Schifano Maria Vadala’ 《Documenta ophthalmologica. Advances in ophthalmology》1995,91(3):255-263
We report on a case of idiopathic uveal effusion syndrome complicated by AION. To our knowledge such an association hasn't been previously described. We suggest that scleral thickening caused obstruction of vortex veins followed by uveal effusion and compression of posterior ciliary arteries within their intrascleral tract, leading to AION. Nevertheless it can't be excluded that AION was the result of mechanical compression on ciliary vessels of optic disc by choroidal detachment. 相似文献
72.
Francesco Franceschi Umile Giuseppe Longo Laura Ruzzini Paolo Simoni Bruno Beomonte Zobel Vincenzo Denaro 《Knee surgery, sports traumatology, arthroscopy》2007,15(3):266-268
Bilateral discoid medial menisci is an extremely rare condition of the knee and it can be associated to other pathological
findings, including anterior portion cyst formation. We report on the clinical features, radiographic findings, treatment
and results of one patient who presented a bilateral medial discoid meniscus combined with posterior portion cyst of the left
knee. To the best of the author’s knowledge, this is the first case of bilateral medial discoid meniscus associated with posterior
portion cyst formation. 相似文献
73.
Roberto Perniola Giuseppe Tamborrino Santo Marsigliante Corrado De Rinaldis 《Journal of oral pathology & medicine》1998,27(6):278-282
The features of enamel hypoplasia in a small group of patients with autoimmune polyendocrinopathy-candidiasis-ectodermal dystrophy (APECED) are described. Using a recently developed method, the authors evaluated quantitatively the amount of defect in each tooth by measuring the width of the hypoplastic lesions and dividing the value by the crown height. They then assessed the degree of damage in each tooth type (from central incisors to second premolars) and patient. Canines were the most severely affected among maxillary and mandibular teeth, but all tooth types were involved. Analysing both the differences between patients and their age at the beginning of the defect, the authors observe that hypoparathyroidism is not responsible for the onset of enamel hypoplasia in APECED, although it may contribute to the damage. 相似文献
74.
75.
β-N-Acetylhexosaminadases in human cerebrospinal fluid and serum of patients with multiple sclerosis
Alessandro Datti Carla Emiliani Giuseppe Capocchi Aldo Orlacchio 《Clinica chimica acta; international journal of clinical chemistry》1991,200(2-3)
β-N-Acetylhexosaminidase activity and isoenzyme have been investigated in normal human cerebrospinal fluid and that of patients with multiple sclerosis. β-N-acetylhexosaminidase activity in normal cerebrospinal fluids has been resolved into five components. The major component was in a form that eluted from DEAE cellulose at the same salt concentration as hexosaminidase As, the isoenzyme previously identified in human serum. Cerebrospinal fluid from patients exhibited a different isoenzyme profile, showing a remarkable increase in a form having a pI which was more acidic than that of As. These changes have a potential use in the diagnosis and further biochemical characterization of multiple sclerosis. 相似文献
76.
77.
Rainaldi Giuseppe; Meneveri Raffaella; Mariani Laura; Ginelli Enrico; Moretti Arcangela; Vatteroni Lucia 《Mutagenesis》1996,11(4):401-404
Clone CSA7 is a CHEF18 hamster cell line that shows an increasedintracellular accumulation of dCTP. To localize the mutationsthat accumulate spontaneously in a functional gene of such amutator phenotype, independent CSA7 mutants of the hypoxanthineguaninephosphoribosyl transferase (hprt) gene were isolated and screenedby a polymerase chain reactionsingle strand conformationpolymorphism technique. Sixty-two percent of mutants produceddetectable changes of the strand migration profile and the mutationswere preferentially localized in the exons 3 (31%) and 6 (62%).The sequencing of such exons revealed that the rate of C baseincorporation was the major mutation pathway and that the Abase of a GGA sequence was the preferential site of misincorporation.
3To whom correspondence should be addressed 相似文献
78.
Giuseppe Micieli Marco Magri Giorgio Sandrini Cristina Tassorelli Giuseppe Nappi 《Cephalalgia : an international journal of headache》1988,8(3):193-201
In this study the variations in pupil diameter induced by different stimuli (dark-light adaptation, light reflex, electric stimulation of the sural nerve) were investigated in episodic (in the active or remission phases) and in chronic cluster headache (CH) patients. Pupil size monitoring was performed with a monocular, infrared TV pupillometer, and sural nerve stimuli were applied after the pain threshold had been measured as the flexion reflex threshold of the biceps femoris muscle (RIII reflex). The results were compared with those obtained in patients with "peripheral" (third neuron) Horner's syndrome and in healthy sex- and age-matched controls. On the symptomatic side we found an impairment of pupil response to light flashes and nociceptive stimuli; similar findings were sometimes evident on the pain-free side, too. These results substantiate previous observations that in cluster headache a dysfunction of the integrative central nervous system pathways also exists intercritically and mostly bilaterally, involving both autonomic regulation and pain perception mechanisms. 相似文献
79.
80.
The role of dietary factors in patients with type 1 (insulin-dependent) diabetes is reviewed by examining three different aspects: the effect of an acute protein load, the effect of dietary protein restriction on the progression of nephropathy and the metabolic effects of low-protein diets. After an acute protein load some impairment of the renal functional reserve may be observed only in patients with type 1 diabetes and overt nephropathy. However, the renal functional reserve is not able to give useful indications of the extent of renal damage and the prognosis of the disease. Both short-term and long-term dietary protein restriction are followed by a significant decrease in glomerular filtration rate (GFR) and albuminuria in type 1 diabetics with incipient nephropathy. In patients with overt nephropathy the long-term administration of a low-protein diet is followed by significant reductions in the rate of decline of GFR and in urinary protein excretion only when started at GFR values higher than 45 ml/min. The rate of functional deterioration when dietary treatment is prescribed seems critical in modulating the effects of a low-protein diet. In addition, low-protein diets may exert important metabolic and clinical effects beyond their supposed effect on progression. Clearly, an adequate dietary regimen is only part of the medical treatment in patients with diabetic nephropathy. 相似文献