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61.
62.
Yalvac S Kayikcioglu F Boran N Tulunay G Kose MF Bilgic S Haberal A 《Cancer investigation》2002,20(5-6):754-758
Ligation of the hypogastric artery has been a standard and effective procedure in controlling massive bleeding in advanced cervical carcinoma. The authors wanted to demonstrate the selective use of embolization of hypogastric or uterine artery to achieve the same end result--the stoppage of vaginal bleeding. In a number of cases, surgical approach may not be appropriate either because of the critically ill patient or because of the highly deformed pelvic anatomy due to radiotherapy or to the recurrence of cancerous tissue. As an alternative therapy, we used selective embolization of the uterine artery in eight patients. In all the patients, embolization served to control bleeding. As the bleeding was brought under control, a gradual recovery of the patient was generally observed. The most common side-effect was temporary severe pain related to ischemia of tumoral tissue. Embolization may be regarded as an effective procedure, which can be used to control massive bleeding in selected cervical cancer patients. 相似文献
63.
64.
E. A. Akpek S. Kahraman A. Yaman E. Bulutçu S. Yavuzer S. Özgen 《European journal of clinical pharmacology》1998,54(6):459-462
Objective: This paper reports the results of a prospective randomized double-blind trial on the effects of pre-operative clonidine
on platelet aggregation.
Methods: Thirty adult (ASA I–II) patients undergoing elective minor orthopaedic surgery were randomly allocated into three groups
of ten patients each. In group I clonidine 2 μg · kg−1, in group II clonidine 4 μg · kg−1 and in group III saline placebo was administered intravenously before the induction of anaesthesia. Anaesthesia was induced
with propofol and vecuronium and maintained with halothane-nitrous oxide. Platelet counts and aggregation tests were performed
before (t0) and 1 h (t1) and 24 h (t24) after administration of the study drug.
Results: Changes in platelet counts among the groups and values over time were not significant. Both maximum rate and intensity of
collagen-induced aggregation in both clonidine groups and maximum intensity of adenosine 5′-diphosphate (ADP)-induced aggregation
in the high-dose clonidine group increased significantly at t1. However, all these increases in aggregation were within the normal ranges.
Conclusion: The effects of both low and high doses of clonidine on platelet aggregation appeared to be minor, and we did not observe
any increases above the normal ranges.
Received: 16 December 1997 / Accepted in revised form: 9 May 1998 相似文献
65.
Ozden I Tekant Y Bilge O Acarli K Alper A Emre A Rozanes I Ozsut H Ariogul O 《American journal of surgery》2005,189(6):702-706
BACKGROUND: Iatrogenic factors became the leading mechanisms of severe cholangitis in a referral center. PATIENTS AND METHODS: The records of the 58 patients treated for severe cholangitis between 1996 and May 2004 (inclusive) were evaluated. RESULTS: The most frequent underlying diseases were periampullary tumors and mid-bile duct carcinomas (22), followed by proximal cholangiocarcinomas (14). The triggering mechanism was an incomplete endoscopic retrograde cholangiopancreatography (ERCP) in 32 patients, incomplete or inappropriate percutaneous transhepatic biliary drainage (PTBD) in 6, apparently successful ERCP and stenting in 1, and percutaneous transhepatic cholangiography in 1. PTBD was the treatment of choice (38). Mortality was 29% (17/58); the major causes were refractory sepsis (8) and incomplete biliary drainage (advanced tumor, technical failure, or hemobilia) (8). CONCLUSIONS: In this series composed predominantly of patients referred after development of sepsis, ERCP and PTBD complications were the leading mechanisms of severe cholangitis. Nonoperative biliary manipulations are invasive procedures with potentially fatal complications. The decisions to perform such procedures and periprocedural management are responsibilities of an experienced multidisciplinary team. 相似文献
66.
We describe a 39-year-old male patient who developed bleomycin-induced pneumonitis 2 years after completion of chemotherapy for nonseminomatous testicular cancer. Bleomycin sometimes causes fatal pulmonary toxicity, including bleomycin-induced pneumonitis. The central event in the development of pneumonitis is endothelial damage of the lung vasculature due to bleomycin-induced cytokines and free radicals. Pulmonary toxicity usually begins at bleomycin administration. The development of bleomycin-induced pneumonitis up to 6 months after bleomycin therapy has also been reported. We report a patient who developed bleomycin-induced pneumonitis 2 years after the initiation of bleomycin-containing chemotherapy regimens. 相似文献
67.
Dökmeci F Engin-Ustün Y Ustün Y Kavas GO Kocatürk PA 《The Journal of reproductive medicine》2004,49(3):200-204
OBJECTIVE: To determine trace element status in plasma and erythrocytes hyperemetic women at presentation and after treatment. STUDY DESIGN: Studies were carried out on 32 women with hyperemesis gravidarum. Thirteen non-vomiting, healthy, pregnant women served as controls. Copper, zinc and magnesium concentrations in both plasma and erythrocytes were estimated before and after treatment. Independent sample t test, paired sample t test, Wilcoxon signed rank test, Mann-Whitney U test, chi2 test, Kruskall-Wallis one-way analysis of variance and Spearman's correlation study were used for statistical analysis. RESULTS: There were no significant differences between the 2 groups in erythrocyte zinc, copper and magnesium concentration. Plasma zinc levels were significantly higher (P = .006), while plasma copper levels were significantly lower (P = .001) in the study group as compared to the controls, but plasma magnesium levels were not significantly altered. Treatment brought a significant decrease in plasma zinc levels (P = .001), increase in plasma copper concentration (P = .001) but no change in erythrocyte zinc, copper or magnesium concentration. When trace element levels were grouped according to the degree of ketonuria, no significant differences were found in the 2 groups. CONCLUSION: Hyperemetic women had normal tissue zinc, copper and magnesium concentrations, and rehydration normalized the plasma zinc and copper levels. Otherwise, no significant effects on trace elements were noted. 相似文献
68.
Arikan C Ozgenc F Akman SA Kilic M Tokat Y Yagci RV Aydogdu S 《Pediatric transplantation》2004,8(6):558-560
Congenital hepatic fibrosis (CHF) is an uncommon autosomal recessive malformation. It may be associated with extrahepatic manifestations such as polycystic kidney disease. The main consequence is portal hypertension and bleeding from varices. Despite liver transplantation as a therapeutic option for this patient, long-term impact of liver transplantation on renal functions of patients with autosomal recessive polycystic kidney disease with associated liver disease is not well known. In this study, we aimed to analyze the patient's renal function after liver transplantation by creatinine clearance, glomerular filtration rate, and renal resistive indexes. Between March 1997 and September 2002, three of 50 orthotopic liver transplantation (OLT) were performed because of CHF associated with ARPKD at Ege University Organ Transplantation and Research Center. Baseline immunosuppression consisted of prednisone and cyclosporine A (CSA). The mean follow-up of the patients was 2.1 yr. Blood urea and creatinine levels were decreased after operation in all patients and remained within the normal range at the sixth and 12th month, whereas the level of the third patient were increased at the 18th month. RRI values of patients were not found different at the sixth month whereas, RRI values of patients were decreased at the 12th month and remained unchanged at the 18th month of follow-up. During the study period hypertension developed in one patient at the 16th month and resolved with antihypertensive treatment and decreasing dosage of CSA. Kidney function has remained satisfactory in all of the patients despite the use of cyclosporine. OLT can provide good survival in patients with CHF associated with ARPKD. 相似文献
69.
70.
We present a 10-month-old child with central pontine myelinolysis (CPM) secondary to chronic active hepatitis due to cytomegalovirus (CMV) infection. A total of 35 paediatric cases of pontine and/or extrapontine myelinolysis are reported and, to our knowledge, CPM secondary to CMV hepatitis in an infant has not been previously reported. The MRI findings are highlighted. 相似文献