全文获取类型
收费全文 | 2559篇 |
免费 | 350篇 |
国内免费 | 23篇 |
专业分类
耳鼻咽喉 | 15篇 |
儿科学 | 110篇 |
妇产科学 | 56篇 |
基础医学 | 231篇 |
口腔科学 | 84篇 |
临床医学 | 374篇 |
内科学 | 553篇 |
皮肤病学 | 62篇 |
神经病学 | 177篇 |
特种医学 | 313篇 |
外科学 | 247篇 |
综合类 | 27篇 |
预防医学 | 387篇 |
眼科学 | 14篇 |
药学 | 114篇 |
肿瘤学 | 168篇 |
出版年
2023年 | 52篇 |
2022年 | 15篇 |
2021年 | 20篇 |
2020年 | 46篇 |
2019年 | 29篇 |
2018年 | 72篇 |
2017年 | 42篇 |
2016年 | 54篇 |
2015年 | 75篇 |
2014年 | 109篇 |
2013年 | 153篇 |
2012年 | 68篇 |
2011年 | 89篇 |
2010年 | 84篇 |
2009年 | 106篇 |
2008年 | 88篇 |
2007年 | 126篇 |
2006年 | 89篇 |
2005年 | 83篇 |
2004年 | 90篇 |
2003年 | 76篇 |
2002年 | 79篇 |
2001年 | 78篇 |
2000年 | 57篇 |
1999年 | 62篇 |
1998年 | 76篇 |
1997年 | 113篇 |
1996年 | 97篇 |
1995年 | 71篇 |
1994年 | 77篇 |
1993年 | 58篇 |
1992年 | 33篇 |
1991年 | 37篇 |
1990年 | 52篇 |
1989年 | 53篇 |
1988年 | 37篇 |
1987年 | 49篇 |
1986年 | 43篇 |
1985年 | 45篇 |
1984年 | 22篇 |
1983年 | 21篇 |
1982年 | 32篇 |
1981年 | 35篇 |
1980年 | 20篇 |
1979年 | 17篇 |
1978年 | 11篇 |
1977年 | 18篇 |
1976年 | 18篇 |
1975年 | 11篇 |
1972年 | 9篇 |
排序方式: 共有2932条查询结果,搜索用时 15 毫秒
11.
12.
13.
MD MS Gregory L Larkin PhD John Moskop MD FACEP Arthur Sanders MD JD FACEP Arthur Derse 《Annals of emergency medicine》1994,24(6)
Confidentiality is a promise rooted in tradition, law andmedical ethics. Emergency physicians treat a variety of patients to whom confidentiality is of vital importance: employees, celebrities, victims of violence or disaster, minors, students, criminals, drug abusers, and patients with STDs. EDs should develop methods of ensuring confidentiality for all patients.34Although confidentiality is an important principle thatshould be respected and guarded, it is not absolute. Various laws mandate disclosure of certain patient information; in addition, an overriding moral duty may occasionally require, a breach of confidentiality. As Beauchamp and Childress noted, “the therapeutic role may sometimes have to yield to ones role as citizen and as protector of the interests of others”.19 In general, however, circumstances requiring a breach of confidentiality are rare. 相似文献
14.
15.
16.
17.
18.
19.
20.
Immunoelectron microscopic studies reveal differences in distribution of sialo-oligosaccharide receptors for Mycoplasma pneumoniae on the epithelium of human and hamster bronchi.
下载免费PDF全文
![点击此处可从《Infection and immunity》网站下载免费的PDF全文](/ch/ext_images/free.gif)
Long-chain sialo-oligosaccharides with poly-N-acetyllactosamine backbones (Ii antigen type) are major host cell receptors for the human pathogen Mycoplasma pneumoniae. Previous immunofluorescence studies of the human bronchial epithelium, using sequence-specific monoclonal antibodies to the branched I-type and linear i-type backbones, have indicated that sialylated and nonsialylated long-chain sequences of both types are richly expressed on the ciliated cells, where they are polarized at the apical aspects. These sequences are lacking in the goblet cells. In the present study, the display of these oligosaccharides has been investigated by electron microscopy (immunogold labelling) in the human bronchial epithelium and in that of the hamster, an animal model commonly used for M. pneumoniae infection. In the human bronchial epithelium, the long-chain branched sequences have been detected along the entire length of the cilia and on microvilli, whereas the linear sequences are confined to the microvilli and the basal aspects of the cilia. On the ciliated epithelial cells of the hamster, by contrast, the branched and linear sequences (sialo- and asialo-) have been detected exclusively on microvilli. A further striking difference is that in the hamster these structures are expressed in abundance on the goblet cells and in the intracellular globules. We suggest that the latter finding may partly explain the relatively large doses of M. pneumoniae required to establish experimental infection in the hamster, as the receptor-bearing secreted mucus may have a protective role in binding to the microorganisms, leading to their clearance by bronchociliary action. 相似文献