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Carmen Gutierrez Angeles Rodriguez Sylvia Palenzuela Carolina Forteza Jose L. Diaz Rossello 《Pediatric and developmental pathology》2000,3(3):271-276
Misalignment of pulmonary vessels with alveolar capillary dysplasia is a rare cause of persistent pulmonary hypertension of
the newborn. Most of the reported cases have been sporadic. We present two consecutive affected siblings with this disorder.
This is the fifth reported family occurrence of this condition. In addition to the pulmonary abnormality, one of our cases
had duodenal atresia.
Received February 2, 1999; accepted June 28, 1999. 相似文献
83.
Julio G. Tejada MD Jesus Saavedra MD Luis Molina MD Alberto Forteza MD Casimiro Gomez MD 《The Annals of thoracic surgery》2001,71(6):189-2035
Echinococcal infestation of the heart is uncommon. We report a case of a 35-year-old man with an hydatid cyst located in distal interventricular septum. Clinical presentation was chest pain and urticaria. Diagnosis was made by echocardiography and magnetic resonance imaging. Surgical resection was performed; the cyst was punctured and its content was drained, hypertonic glucose solution was instilled for sterilization, and it was removed. The patient did well and remains asymptomatic. Diagnosis and ultimate surgical treatment of this disease prevented potentially lethal complications such as cyst rupture with embolic phenomena and anaphylactic shock. 相似文献
84.
Increased expression of growth hormone and prolactin receptors in hepatocellular carcinomas 总被引:6,自引:0,他引:6
García-Caballero T Mertani HM Lambert A Gallego R Fraga M Pintos E Forteza J Chevallier M Lobie PE Vonderhaar BK Beiras A Morel G 《Endocrine》2000,12(3):265-271
The liver is an essential target tissue for growth hormone (GH) and prolactin (PRL). The aim of this study was to determine
the in situ expression of growth hormone receptor (GHR) and prolactin receptor (PRLR) in hepatocellular carcinomas and to compare the
results with normal liver. For this purpose, in situ hybridization (ISH) and immunohistochemical techniques were performed and several tests were conducted to validate the results.
By radioactive ISH, all the hepatocellular carcinomas studied showed labeling for GHR and PRLR mRNAs. Relative expression
levels, determined by computer-assisted microdensity, were higher in hepatocellular carcinomas than in normal liver. Immunohistochemistry
led us to confirm the constant expression of both receptor proteins in hepatocellular carcinomas and normal liver and to demonstrate
their localization not only in the cytoplasm but also in the nucleus. These results confirm that the liver is a major GH and
PRL target tissue and suggest that in hepatocellular carcinomas the proliferative effects of these hormones may be increased
by a higher expression of their receptors. 相似文献
85.
Manuel Raya Cruz Cristina Gállego Lezaún Mercedes García Gasalla Carmen Cifuentes Luna Teodoro Forteza Forteza Victoria Fernández-Baca Carmen Gallegos Álvarez Antonio Payeras Cifre 《Enfermedades infecciosas y microbiología clínica》2014
Introduction
Q fever is a widespread zoonotic infection caused by Coxiella burnetii (C. burnetii). Acute infection varies from a self-limited flu-like illness to pneumonia or hepatitis.Methods
A retrospective case study from March 2003 to December 2011 was conducted in the Hospital Son Llàtzer in Palma de Mallorca. Acute Q-fever was diagnosed in a patient with clinical suspicion and IgM in phase ii positive (≥ 1/40), with a positive IgG (≥1/80), or when IgG seroconversion was observed during convalescence. A total of 87 cases of acute Q fever were diagnosed. The median age was 50 years (range 21-89), and 69 (79.3%) were male. Fever and headache were the most common symptoms. Pneumonia was diagnosed in 39 (44.8%) patients, febrile episode in 21 (24.1%), and acute hepatitis in 23 (25.6%). Increased serum transaminases were observed in 19 (21.8%). Doxycycline was prescribed in 29 cases (33.4%). There were 30 (34.5%) patients lost to follow up after hospital discharge. A favorable outcome was observed in all other cases. Only one new case progressed to chronic Q fever.Results
A total of 87 cases of acute Q fever were diagnosed. The median age was 50 years (range 21-89), and 69 (79.3%) were male. Fever and headache were the most common symptoms. Pneumonia was diagnosed in 39 (44.8%) patients, febrile episode in 21 (24.1%), and acute hepatitis in 23 (25.6%). Increased serum transaminases were observed in 19 (21.8%). Doxycycline was prescribed in 29 cases (33.4%). There were 30 (34.5%) patients lost to follow up after hospital discharge. A favorable outcome was observed in all other cases. Only one new case progressed to chronic Q fever.Conclusion
Acute Q fever acute is common our environment. Pneumonia was the most common clinical presentation. Even although doxycycline was prescribed in a small number of patients, a favorable outcome was observed in all cases. 相似文献86.
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