全文获取类型
收费全文 | 2486篇 |
免费 | 176篇 |
国内免费 | 12篇 |
专业分类
耳鼻咽喉 | 16篇 |
儿科学 | 16篇 |
妇产科学 | 26篇 |
基础医学 | 303篇 |
口腔科学 | 111篇 |
临床医学 | 180篇 |
内科学 | 737篇 |
皮肤病学 | 13篇 |
神经病学 | 154篇 |
特种医学 | 72篇 |
外科学 | 561篇 |
综合类 | 8篇 |
预防医学 | 68篇 |
眼科学 | 22篇 |
药学 | 92篇 |
中国医学 | 9篇 |
肿瘤学 | 286篇 |
出版年
2023年 | 15篇 |
2022年 | 38篇 |
2021年 | 74篇 |
2020年 | 42篇 |
2019年 | 59篇 |
2018年 | 83篇 |
2017年 | 61篇 |
2016年 | 73篇 |
2015年 | 71篇 |
2014年 | 90篇 |
2013年 | 141篇 |
2012年 | 198篇 |
2011年 | 193篇 |
2010年 | 110篇 |
2009年 | 96篇 |
2008年 | 173篇 |
2007年 | 192篇 |
2006年 | 151篇 |
2005年 | 154篇 |
2004年 | 134篇 |
2003年 | 134篇 |
2002年 | 125篇 |
2001年 | 23篇 |
2000年 | 31篇 |
1999年 | 29篇 |
1998年 | 16篇 |
1997年 | 19篇 |
1996年 | 7篇 |
1995年 | 8篇 |
1994年 | 13篇 |
1993年 | 10篇 |
1992年 | 10篇 |
1991年 | 12篇 |
1990年 | 8篇 |
1989年 | 7篇 |
1988年 | 5篇 |
1987年 | 5篇 |
1986年 | 13篇 |
1985年 | 5篇 |
1984年 | 5篇 |
1983年 | 3篇 |
1982年 | 3篇 |
1981年 | 2篇 |
1980年 | 4篇 |
1979年 | 4篇 |
1976年 | 2篇 |
1972年 | 4篇 |
1971年 | 3篇 |
1970年 | 2篇 |
1969年 | 3篇 |
排序方式: 共有2674条查询结果,搜索用时 23 毫秒
81.
82.
83.
Pedro Carrilho-Ferreira Ana G. Almeida Fausto J. Pinto 《Current heart failure reports》2014,11(4):393-403
Left ventricular non-compaction (LVNC) is thought to arise from arrest of the normal process of trabecular remodeling or “compaction” that takes place during embryonic life and is characterized by the presence of a two-layered ventricular wall, with a compact epicardial layer and a non-compacted endocardial layer. It is an uncommon condition that can occur isolated or in association with other disorders, including congenital heart anomalies and mitochondrial or musculoskeletal disorders. Both familial and sporadic forms are recognized, and several responsible genes have been identified, although only a minority of patients can be successfully genotyped. The diagnosis is usually made by echocardiography, but cardiac magnetic resonance imaging has been used increasingly. Management is mainly empirical and directed at the major clinical manifestations: heart failure, arrhythmias, and systemic embolic events. This article will review the major features of LVNC and present new trends in the diagnosis and management of this intriguing condition. 相似文献
84.
85.
Poorly differentiated neuroendocrine carcinomas (PDNECs) of the gastroenteropancreatic system (GEP) are a heterogeneous group of aggressive malignancies with a high propensity for distant metastases and an ominous prognosis. They have traditionally been divided into small and large cell subtypes on morphological grounds. However, histological diagnosis needs to be supported by immunohistochemistry to avoid possible misdiagnoses either with the more frequent poorly differentiated adenocarcinomas and squamous cell carcinomas or with lymphomas and mesenchymal neoplasms. Although it is well known that GEP PDNECs are associated with a poor prognosis, data from some published studies seem to suggest that there is a fraction of patients with PDNECs who have better survival than expected. GEP PDNECs are currently classified according to the criteria proposed in the 2010 WHO classification. They are simply called neuroendocrine carcinomas (NECs) and are defined by mitotic count >20?×?10 HPF and/or Ki-67 labeling index >20 %. However, a few recent papers have indicated that some NECs, as defined by the 2010 WHO scheme, do not show a poorly differentiated morphology as expected. This category seems to show a better prognosis and, especially, does not respond to cisplatin-based chemotherapy, which represents the goal standard therapeutic approach to high-grade PDNECs. In the present review, the main morphological, immunohistochemical, and prognostic features will be discussed as well as the opportunity to introduce a new category characterized by well to moderately differentiated morphology associated with high proliferation (mitotic count >20?×?10 HPF and/or Ki-67 index >20 %). 相似文献
86.
Fausto Biancari Tomas Gudbjartsson Jouni Heikkinen Vesa Anttila Timo Mäkikallio Anders Jeppsson Linda Thimour-Bergström Carmelo Mignosa Antonino S. Rubino Kari Kuttila Jarmo Gunn Jan-Ola Wistbacka Kari Teittinen Kari Korpilahti Francesco Onorati Giuseppe Faggian Giulia Vinco Corrado Vassanelli Flavio Ribichini Tatu Juvonen Tomas A. Axelsson Axel F. Sigurdsson Pasi P. Karjalainen Ari Mennander Olli Kajander Markku Eskola Erkki Ilveskoski Veronica D'Oria Marisa De Feo Tuomas Kiviniemi K.E. Juhani Airaksinen 《The American journal of cardiology》2014
87.
Ardenghi TM Vargas-Ferreira F Piovesan C Mendes FM 《Oral health & preventive dentistry》2012,10(1):17-27
Purpose: To assess the age the of the first dental visit and the association of self-perceived oral health, socioeconomic and clinical indicators with healthcare utilisation in Brazilian preschool children. Materials and Methods: An epidemiological survey with 455 5- to 59-month-old children was conducted on National Children's Vaccination Day in Santa Maria, RS, Brazil. Data about age and reasons for the first dental visit, healthcare utilisation, socioeconomic status and self-perceived oral health were collected by means of a parental semi-structured questionnaire. Calibrated examiners evaluated the prevalence of dental caries (WHO) and dental trauma. The assessment of the association used Poisson regression models (prevalence ratio; 95% confidence interval [CI]). Results: A total of 24.2% (95% CI: 20.3% to 28.4%) of the study sample had already had a first dental visit. Older children, those with dental caries and dental trauma and whose mothers had a higher level of education were more likely to have gone to the dentist. Children of low socioeconomic status were more likely to have visited public than private healthcare services. The reasons for the first dental visit were associated with clinical indicators of the sample. The distribution of utilisation of the types of oral healthcare services (public or private) varied across the socioeconomic groups. Non-white children with dental caries and dental trauma tended to visit a dentist only for treatment reasons. Conclusion: Socioeconomic and clinical indicators are associated with the use of dental services, indicating the need for strategies to promote public health and reorientation of services that facilitate dental access for preschool children. 相似文献
88.
Petrelli F Borgonovo K Cabiddu M Lonati V Barni S 《Journal of cancer research and clinical oncology》2012,138(2):179-187
Background
Iron supplementation could improve the hematopoietic response of erythropoiesis-stimulating agents (ESAs) used for chemotherapy-induced anemia. 相似文献89.
Alberto Monje Jia‐Hui Fu Hsun‐Liang Chan Fernando Suarez Pablo Galindo‐Moreno Andrés Catena Hom‐Lay Wang 《Journal of periodontology》2013,84(12):1783-1791
Background: This meta‐analysis of prospective clinical trials was conducted to determine the effects of dental implant length and width on implant survival rate of short (<10 mm) implants. Methods: An electronic search of the PubMed database for relevant studies published in English from November 1998 to March 2012 was performed. Selected studies were randomized clinical trials, human clinical trials, or prospective trials with a clear aim of investigating the success or survival rate of short (<10 mm) implants. Results: Eight studies fulfilled the inclusion criteria and were subsequently analyzed. A total of 525 short (<10 mm) dental implants were analyzed, of which 253 were 3.5 mm in diameter (48.19%), 151 were 4.0 mm (28.76%), 90 were 4.1 mm (17.14%), 21 were 4.8 mm (4%), and 10 were 5.1 mm (1.9%). All implants included in this meta‐analysis had a follow‐up period of 12 to 72 months. The included studies reported on the survival rate and diameter of the implants. Six of the studies used “short implants” (7 to 9 mm), and the remaining were classified as “extra‐short implants” (≤6 mm). Five‐year estimated failure rates were 1.61% and 2.92%, respectively, for extra‐short and short implants (z = ?3.49, P <0.001, 95% confidence interval = 0.51% to 4.10%). Furthermore, it was found that the wider the implant, the higher the failure rate (estimated failure rate = 2.36%, 95% confidence interval = 1.07% to 5.23%). Conclusions: Neither implant length nor width seemed to significantly affect the survival rate of short implants (<10 mm). Nonetheless, further well‐designed randomized clinical trials are needed to confirm these findings. 相似文献
90.
R?mulo?Vaz?Machry Simone?Tuchtenhagen Bernardo?Antonio?Agostini Carlos?Roberto?da Silva Teixeira Chaiana?Piovesan Fausto?Medeiros?Mendes Thiago?Machado?ArdenghiEmail author 《BMC oral health》2013,13(1):60