全文获取类型
| 收费全文 | 57407篇 |
| 免费 | 5583篇 |
| 国内免费 | 3624篇 |
专业分类
| 耳鼻咽喉 | 476篇 |
| 儿科学 | 1079篇 |
| 妇产科学 | 602篇 |
| 基础医学 | 5471篇 |
| 口腔科学 | 921篇 |
| 临床医学 | 7887篇 |
| 内科学 | 7305篇 |
| 皮肤病学 | 623篇 |
| 神经病学 | 2410篇 |
| 特种医学 | 1802篇 |
| 外国民族医学 | 26篇 |
| 外科学 | 4530篇 |
| 综合类 | 11739篇 |
| 现状与发展 | 6篇 |
| 一般理论 | 7篇 |
| 预防医学 | 5007篇 |
| 眼科学 | 1291篇 |
| 药学 | 7107篇 |
| 63篇 | |
| 中国医学 | 4303篇 |
| 肿瘤学 | 3959篇 |
出版年
| 2024年 | 806篇 |
| 2023年 | 1033篇 |
| 2022年 | 2238篇 |
| 2021年 | 2757篇 |
| 2020年 | 2370篇 |
| 2019年 | 1797篇 |
| 2018年 | 1787篇 |
| 2017年 | 1844篇 |
| 2016年 | 1672篇 |
| 2015年 | 2647篇 |
| 2014年 | 3297篇 |
| 2013年 | 3183篇 |
| 2012年 | 4817篇 |
| 2011年 | 5246篇 |
| 2010年 | 3854篇 |
| 2009年 | 3154篇 |
| 2008年 | 3564篇 |
| 2007年 | 3332篇 |
| 2006年 | 3082篇 |
| 2005年 | 2729篇 |
| 2004年 | 1891篇 |
| 2003年 | 1667篇 |
| 2002年 | 1321篇 |
| 2001年 | 1043篇 |
| 2000年 | 919篇 |
| 1999年 | 915篇 |
| 1998年 | 522篇 |
| 1997年 | 551篇 |
| 1996年 | 381篇 |
| 1995年 | 325篇 |
| 1994年 | 266篇 |
| 1993年 | 187篇 |
| 1992年 | 222篇 |
| 1991年 | 186篇 |
| 1990年 | 151篇 |
| 1989年 | 147篇 |
| 1988年 | 108篇 |
| 1987年 | 136篇 |
| 1986年 | 88篇 |
| 1985年 | 74篇 |
| 1984年 | 59篇 |
| 1983年 | 31篇 |
| 1982年 | 25篇 |
| 1981年 | 32篇 |
| 1980年 | 23篇 |
| 1979年 | 19篇 |
| 1978年 | 25篇 |
| 1977年 | 16篇 |
| 1976年 | 12篇 |
| 1974年 | 13篇 |
排序方式： 共有10000条查询结果，搜索用时 0 毫秒
71.
Bo-Hua Li Shan-Xi Wang Jun Li Fu-Guo Huang Zhou Xiang Yue Fang Gang Zhong Min Yi Xiao-Dan Zhao Lei Liu 《中华创伤杂志(英文版)》2018,21(4):193-196
Purpose
To investigate the early and mid-term results of open reduction and internal fixation (ORIF) with transarticular external fixation (TEF) but no deltoid ligament repair (DLR) in the treatment of supination-external rotation type IV equivalent (SER IV E) ankle fractures (AO/OTA classification 44-B 3.1) and provide evidence for clinical practice.Methods
This study cohort consisted of 22 patients with SER IV E ankle fractures that underwent ORIF with TEF but no DLR between December 2011 and December 2014. There were 13 males and 9 females, mean age 38.9 years (range, 17–73 years). Eight cases involved the left side and 14 the right side. The causes of fractures included road traffic accidents (11 cases), falling from height (6 cases) and sports injuries (5 cases). The mean period of hospitalization was 9.8 days (range, 6–14 days). For all the patients, MRI and three-dimensional CT were done before surgery and X-rays done preoperatively and during follow-ups. The external frame was kept for 8–10 weeks. The preoperative American Orthopedic Foot and Ankle Society (AOFAS) ankle-hindfoot score was 56.86 ± 4.400, the Medical Outcomes Short Form 36-item (SF-36) questionnaire score was 57.41 ± 4.102 and the visual analog score (VAS) was 5.50 ± 1.058. Patients' main complaints about inconvenience of daily life were also recorded.Results
All the 22 patients were followed up for 24–63 months (mean, 33.6 months). None of them developed nonunion during the follow-up; pin site infection was observed in one patient and posttraumatic osteoarthritis in another. At the final follow-up, the average AOFAS score, SF-36 score and VAS score were respectively 90.59 ± 5.096, 79.59 ± 5.394 and 1.82 ± 1.181, which were significantly improved compared with the preoperative data (t = 26.221, p < 0.001; t = 11.910, p < 0.001; t = 11.571, p < 0.001). The therapeutic effect was excellent in 13 cases, good in 7 cases and fair in 2 cases, with a good-excellent rate of 90.9%. Patients' main complaints were inconvenience of clothing (17 cases) and extremity cleaning (5 cases).Conclusion
In the treatment of SER IV E ankle fractures, ORIF with TEF but no DLR can achieve satisfactory outcome, but long-term effect should be confirmed by large sample randomized controlled trials. 相似文献72.
Guideline and preliminary clinical practice results for dose specification and target delineation for postoperative radiotherapy for oral cavity cancer 
下载免费PDF全文
下载免费PDF全文 73.
Desirée Schubert Marie-Christine Klein Sarah Hassdenteufel Andrés Caballero-Oteyza Linlin Yang Michele Proietti Alla Bulashevska Janine Kemming Johannes Kühn Sandra Winzer Stephan Rusch Manfred Fliegauf Alejandro A. Schäffer Stefan Pfeffer Roger Geiger Adolfo Cavalié Hongzhi Cao Fang Yang Bodo Grimbacher 《The Journal of allergy and clinical immunology》2018,141(4):1427-1438
74.
75.
Xia Meng Xinrong Sun Yonghong Zhang Hongyang Shi Wenjing Deng Yanqin Liu Guizuo Wang Ping Fang Shuanying Yang 《Inflammation》2018,41(6):2079-2089
76.
77.
Yang Jing Du Fen Zhou Xiaoliu Wang Lixia Li Senyang Fang Rui Zhao Junlong 《Parasitology research》2018,117(8):2623-2633
Parasitology Research - Chronic clinical Toxoplasma gondii (T. gondii) infection is the primary disease state that causes severe encephalitis. CD44 is a member of the cell adhesion molecule family... 相似文献
78.
79.
Cardiovascular disease, which is often driven by hypercholesterolemia and subsequent coronary atherosclerosis, is the number-one cause of morbidity and mortality in the United States. Based on long-term epidemiological studies, high-density lipoprotein cholesterol (HDL-C) levels are inversely correlated with risk for coronary artery disease (CAD). HDL-mediated reverse cholesterol transport (RCT) is responsible for cholesterol removal from the peripheral tissues and return to the liver for final elimination.1 In atherosclerosis, intraplaque angiogenesis promotes plaque growth and increases plaque vulnerability. Conceivably, the acceleration of RCT and disruption of intraplaque angiogenesis would inhibit atherosclerosis and reduce CAD. We have identified a protein called apoA-I binding protein (AIBP) that augments HDL functionality by accelerating cholesterol efflux. Furthermore, AIBP inhibits vascular endothelial growth factor receptor 2 activation in endothelial cells and limits angiogenesis.2 The following discusses the prospect of using AIBP as a novel therapeutic approach for the treatment of CAD. 相似文献
80.