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61.
The cognitive profile of individuals with Down syndrome (DS) is known to be characterized by an impaired executive functioning, but inhibition-related processes have not been extensively examined in this setting. The aim of the present study was to investigate whether individuals with DS have any specific or general deficit in inhibitory processes. Tasks measuring prepotent response inhibition (the animal Stroop test), proactive interference (proactive interference task and intrusion errors), and response to distracters (directed forgetting task) were administered together with a working memory test to 19 individuals with DS and 19 typically developing (TD) children matched for mental age. Confirming previous findings, our results showed that the DS group performed less well in a verbal working memory task than the TD children. Analyzing our findings for the three inhibitory tasks yielded a picture of the DS children having a generalized difficulty in suppressing information that is irrelevant, or no longer relevant, to the goals of the task. These results suggest that DS is related not to specific, but rather to generalized inhibitory difficulties. 相似文献
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Effect of resveratrol on experimental non‐alcoholic fatty liver disease depends on severity of pathology and timing of treatment 下载免费PDF全文
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Alberto Prats‐Galino Martin Čapek Miguel A. Reina Erika Cvetko Barbora Radochova R. Shane Tubbs Marija Damjanovska Tatjana Stopar Pintarič 《Clinical anatomy (New York, N.Y.)》2018,31(3):424-431
The general microscopic characteristics of nerves are described in several textbooks of histology, but the specific microanatomies of most nerves that can be blocked by anesthesiologists are usually less well known. Our objective was to evaluate the 3D reconstruction of nerve fascicles from optical projection tomography images (OPT) and the ability to undertake an internal navigation exploring the morphology in detail, more specifically the fascicular interconnections. Median and lingual nerve samples were obtained from five euthanized piglets. OPT images of the samples were acquired and 3D reconstruction was performed. The OPT technique revealed the inner structure of the nerves at high resolution, including large and small fascicles, perineurium, interfascicular tissue, and epineurium. The fascicles were loosely packed inside the median nerve and more densely so in the lingual nerve. Analysis of the 3D models demonstrated that the nerve fascicles can show six general spatial patterns. Fascicular interconnections were clearly identified. The 3D reconstruction of nerve fascicles from OPT images opens a new path for research into the microstructure of the inner contents of fascicular nerve groups and their spatial disposition within the nerve including their interconnections. These techniques enable 3D images of partial areas of nerves to be produced and could became an excellent tool for obtaining data concerning the 3D microanatomy of nerves, essential for better interpretation of ultrasound images in clinical practice and thus avoiding possible neurological complications. Clin. Anat. 31:424–431, 2018. © 2017 Wiley Periodicals, Inc. 相似文献
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Norma Olvera Allison Dempsey Erika Gonzalez Catherine Abrahamson 《Eating behaviors》2013,14(4):513-517
PurposeTo assess the association among parent and peer weight-related teasing, emotional eating, and weight control behaviors in minority girls.Methods141 Hispanic and African American preadolescent girls (mean age = 11.1 years, SD = 1.5 years) participated. Most of the participants were of Hispanic origin, had a bicultural orientation, and were obese. Participants completed surveys assessing weight-related teasing, emotional eating, weight control behaviors, demographic, and acculturation characteristics. Body weight and height were also assessed. Hierarchical regression analyses were run to determine the associations among study variables.ResultsFifty-nine percent of participants reported being weight-related teased by peers and 42% participants reported weight-related teasing by parents. Weight-related teasing by parent was associated with emotional eating and binge eating, whereas peer weight-related teasing was only associated with emotional eating.ConclusionsFindings demonstrated the differential association of weight-related teasing from peers and parents to emotional and binge eating in minority girls. 相似文献
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Inspired originally by peptides that traverse biological barriers, research on molecular transporters has since identified the key structural requirements that govern cellular entry, leading to new, significantly more effective and more readily available agents. These new drug delivery systems enable or enhance cellular and tissue uptake, can be targeted, and provide numerous additional advantages of significance in imaging, diagnostics and therapy. 相似文献
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在我们颈部甲状软骨下端,有一个长得像蝴蝶一样的腺体,横跨于气管前方,这个腺体叫做甲状腺。甲状腺属于内分泌器官,它的作用是调整机体代谢。一旦甲状腺功能失常,就会引起疾病。在1型或2型糖尿病患者之中,甲状腺疾病的发病率都比常人要高。 相似文献
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Identification of fungal candidates for asthma protection in a large population‐based study 下载免费PDF全文