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91.
Mert O. Karataş Selami Günal Ahmet Mansur Bülent Alıcı İsmail Özdemir 《Archiv der Pharmazie》2020,353(6):2000013
Catechol-containing imidazolium (four) and benzimidazolium chlorides (eight) were synthesized to evaluate their antimicrobial properties. All the compounds were fully characterized using 1H and 13C nuclear magnetic resonance, liquid chromatography–mass spectrometry, infrared spectroscopic methods, and elemental analyses. Antimicrobial activities of the compounds were tested against the bacteria Escherichia coli, Pseudomonas aeruginosa, Acinetobacter baumannii, Klebsiella pneumoniae, Staphylococcus aureus, methicillin-resistant S. aureus (MRSA), Enterococcus faecalis, and the fungal strains Candida albicans and Candida glabrata, and promising results were achieved. The two most important benzyl-substituted benzimidazolium chlorides, 3l and 3k , showed comparable activity to vancomycin against MRSA. 相似文献
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Keles GC Cetinkaya BO Ayas B Isildak I Diraman E Koprulu H Acikgoz G 《Clinical oral investigations》2007,11(4):369-376
The hypothesis, a relationship between gingival tissue platelet activating factor (PAF) levels and healing after periodontal
surgery, was tested by measuring PAF levels in gingival tissues collected from sites that had undergone flap surgery and guided
tissue regeneration (GTR) or flap surgery alone. Using a split-mouth design, 20 intrabony defects were randomly assigned to
treatment with flap surgery and GTR (group 1) or with flap surgery alone (group 2). Gingival tissue samples were obtained
at surgery (baseline) and at 6-month follow-up evaluation visit. One half of each sample was used for analysis of PAF levels
by high-performance liquid chromatography, and the other half of the sample was used for histomorphometric analysis that included
measurements of number and diameter of blood vessels. PAF levels and diameter of blood vessels were significantly decreased
(p < 0.01), and the number of blood vessels was significantly increased (p < 0.05) in both groups after 6 months compared to the baseline values. Postoperative number of blood vessels were significantly
higher in group 1 (p < 0.05), whereas there was no significant difference in postoperative PAF levels between the two groups (p > 0.05). Based on the reported results, it is suggested that a decrease in gingival PAF levels might be found after conventional
and regenerative periodontal surgery. 相似文献
95.
Teoman I Ozmeriç N Ozcan G Alaaddinoğlu E Dumlu S Akyön Y Baloş K 《Clinical oral investigations》2007,11(3):201-205
The aim of this study was to compare different methods of detection of Helicobacter pylori (H. pylori) in the dental plaque of dyspeptic patients. After recording the clinical indices, culture and polymerase chain reaction
(PCR) methods were performed on plaque samples, while rapid urease test in addition to these tests was carried on gastric
samples from 67 dyspeptic patients who attended for an upper gastrointestinal endoscopy. Forty-seven of 67 patients were H. pylori-positive in gastric biopsy material whereas the microbial dental plaque from 19 patients demonstrated H. pylori positivity detected by PCR. Among the patients, 25.4% harbored H. pylori both in the stomach and in microbial dental plaque. No significant correlations were found among the presence of H. pylori in the stomach, in plaque, and clinical variables (P > 0.05). Although oral hygiene was observed optimal and the mean of pocket depth was not found to be higher, the prevalence
of H. pylori was observed to be higher in dental plaque. According to our results, PCR technique gave the highest detection rate both
in gastric biopsy and in dental plaque compared to the other methods used. 相似文献
96.
Emine Ozlem Gur Cokun Onak Emine Ebru Bayar Aye Yazc brahim Kokulu Selda Hacyanl Osman Nuri Dilek 《The breast journal》2020,26(3):517-519
A 47‐year‐old male presented to our clinic with complaints of mass in both breasts. In the patient's history, he had undergone low anterior resection for rectum mucinous adenocarcinoma 2 years ago. The masses in both breasts of the patient were excised. Mucinous adenocarcinoma metastases were reported in the pathologic evaluation of the masses. Metastasis should be considered in patients with bilateral breast mass and previously diagnosed cancer even if the patient is male. 相似文献
97.
Hasan Ali Inal Zeynep Ozturk Inal Sultan Mermer Emine Aksoy Ahmet Murat Bayraktar Ummugulsum Can 《Andrologia》2020,52(3):e13507
Our aim was to explore the existence of a possible relationship of sperm motility with serum 25-hydroxyvitamin D3 (25-OH VD) levels and with ischaemia-modified albumin ( IMA) levels in infertile Turkish men. A total of 30 men with nonobstructive azoospermia (no spermatozoa in ejaculate), 30 men with oligospermia (total progressive motile sperm count (TPMSC) <15 × 106/ml) and 33 fertile men with normospermia (with at least one child, as the control group) were enrolled in the study. The mean 25-OH VD levels for groups 1, 2 and 3 were 9.31 ± 6.46, 19.71 ± 12.80 and 30.52 ± 12.49 respectively (p < .05). There was a statistically significant difference in serum IMA levels among the groups (479.32 ± 307.56 vs. 296.37 ± 127.27 vs. 150.04 ± 81.05, respectively; p < .05). A positive correlation between serum 25-OH VD levels and TPMSC, and a negative correlation between TPMSC and serum IMA levels were determined. Infertile men had lower serum 25-OH VD and higher IMA levels than fertile men, with a positive correlation between serum 25-OH VD levels and TPMSC, and a negative correlation between TPMSC and serum IMA levels. Vitamin D supplementation may increase the sperm motility. 相似文献
98.
Selim Alcay Burcu Ustuner Ahmet Aktar Emine Mulkpinar Muhammed Duman Mustafa Akkasoglu Mehmet Cetinkaya 《Andrologia》2020,52(4):e13555
The objective of this study was to determine the optimum concentrations of rainbow trout seminal plasma (RTS) supplemented extenders for goat semen quality at post-thaw and after incubation. Five sexually mature Saanen goat (Capra aegagrus hircus) were used for semen collection. Pooled semen was diluted with soybean lecithin-based extender without RTS (control) or supplemented with different concentrations of RTS (1%, 2%, 4% or 8%), at a final concentration of 150 × 106 spermatozoon/ml. Sperm motility, plasma membrane functional integrity (HOST), damaged acrosome (PSA-FITC), mitochondrial activity (rhodamine123) and DNA integrity (TUNEL) were evaluated. Spermatological parameters were evaluated at post-thaw and after 6 hr incubation. RTS8 group preserved sperm motility, acrosomal integrity, plasma membrane functional integrity and mitochondrial function better than the control group (p < .05). The study demonstrated that RTS supplemented lecithin-based extenders have useful effects on goat spermatozoa. In addition, the results of the current study represented the positive effect of using 8% RTS supplemented extender. 相似文献
99.
Simsek Mert Kocer Ali Mert Cevik Seda Sen Emine Elgin Ufuk 《Albrecht von Graefes Archiv fur klinische und experimentelle Ophthalmologie》2020,258(7):1493-1501
Graefe's Archive for Clinical and Experimental Ophthalmology - To evaluate vascular microcirculation changes of the optic nerve head (ONH) in the patients with asymmetric pseudoexfoliative... 相似文献
100.
Nedra Touj Abdullah S. Al-Ayed Mathieu Sauthier Lamjed Mansour Abdel Halim Harrath Jamil Al-Tamimi Ismail
zdemir Sedat Yaar Naceur Hamdi 《RSC advances》2018,8(70):40000
N,N-Substituted benzimidazole salts were successfully synthesized and characterized by 1H-NMR, 13C {1H} NMR and IR techniques, which support the proposed structures. Catalysts generated in situ were efficiently used for the carbonylative cross-coupling reaction of 2 bromopyridine with various boronic acids. The reaction was carried out in THF at 110 °C in the presence of K2CO3 under inert conditions and yields unsymmetrical arylpyridine ketones. All N,N-substituted benzimidazole salts 2a–i and 4a–i studied in this work were screened for their cytotoxic activities against human cancer cell lines such us MDA-MB-231, MCF-7 and T47D. The N,N-substituted benzimidazoles 2e and 2f exhibited the most cytotoxic effect with promising cytotoxic activity with IC50 values of 4.45 μg mL−1 against MDA-MB-231 and 4.85 μg mL−1 against MCF7 respectively.The in situ prepared four component system Pd(OAc)2, 1,3-dialkylbenzimidazolium halides 2a–i and 4a–i, K2CO3 under CO atmosphere catalyses carbonylative cross-coupling reaction of 2-bromopyridine with various boronic acids to yield unsymmetrical arylpyridine ketones. 相似文献