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11.
Jaume Alijotas-Reig Manel Casellas-Caro Raquel Ferrer-Oliveras Elisa Llurba-Olive Eduard Hermosilla Miquel Vilardell-Tarres Lluis Cabero-Roura 《American journal of reproductive immunology (New York, N.Y. : 1989)》2008,60(3):229-237
Problem Anti-beta2 -Glicoprotein-1 antibodies (anti-β2 GPI-ab) have been related to recurrent miscarriage (RM) with conflicting results. The aim was to evaluate the role of anti-β2 -GPI-ab as unique biological marker in RM related to antiphospholipid (aPL).
Method of study A cohort study that included 59 cases, divided in two groups, was designed: group 1 comprised 43 pregnant women with 'obstetric' antiphospholipid syndrome (APS) and group 2 included 16 cases with similar complaints but only having repeatedly anti-β2 -GPI-ab. Previous thrombosis and/or inherited thrombophilia were excluded. Lupus anticoagulant, anticardiolipin antibodies (aCA), anti-β2 -GPI-ab, and other autoantibodies were analyzed. Miscarriages, premature births, pre-eclampsia, live births, placental and systemic thromboses were studied.
Results No differences in previous obstetric complications were detected ( P = 1.00–0.164). After the treatment, differences in number of obstetric complications were not seen ( P = 1.00). Live births were similar in two groups (88.4% and 93.7%; P = 1.00). Placental thrombosis was equal in both groups, 93.3% versus 80% ( P = 1.00).
Conclusion These results suggest that anti-β2 -GPI-ab may be considered a biological marker for obstetric APS. 相似文献
Method of study A cohort study that included 59 cases, divided in two groups, was designed: group 1 comprised 43 pregnant women with 'obstetric' antiphospholipid syndrome (APS) and group 2 included 16 cases with similar complaints but only having repeatedly anti-β
Results No differences in previous obstetric complications were detected ( P = 1.00–0.164). After the treatment, differences in number of obstetric complications were not seen ( P = 1.00). Live births were similar in two groups (88.4% and 93.7%; P = 1.00). Placental thrombosis was equal in both groups, 93.3% versus 80% ( P = 1.00).
Conclusion These results suggest that anti-β
12.
Santos Marília Neves Azeredo Catarina Machado Rinaldi Ana Elisa Madalena 《Maternal and child health journal》2022,26(7):1496-1506
Maternal and Child Health Journal - The aim of this study was to estimate the association between individual and contextual characteristics related to maternal work and exclusive breastfeeding... 相似文献
13.
Herkama Sanna Kontio Mari Sainio Miia Turunen Tiina Poskiparta Elisa Salmivalli Christina 《Prevention science》2022,23(6):954-968
Prevention Science - The long-term sustainment of bullying prevention programs has rarely been investigated. This study addresses this gap by identifying facilitators and barriers to the systematic... 相似文献
14.
Vincenzo Di Stefano Raffaele Ornello Andrea Gagliardo Angelo Torrente Elisa Illuminato Valeria Caponnetto Ilaria Frattale Raffaella Golini Chiara Di Felice Fabiola Graziano Maria Caccamo Davide Ventimiglia Salvatore Iacono Gabriella Matarazzo Francesco Armetta Giuseppe Battaglia Alberto Firenze Simona Sacco Filippo Brighina 《Nutrients》2021,13(4)
Background: The restrictions taken to control the rapid spread of COVID-19 resulted in a sudden, unprecedented change in people’s lifestyle, leading to negative consequences on general health. This study aimed to estimate the impact of such changes on migraine severity during 2020 March–May lockdown. Methods: Patients affected by migraine with or without aura, diagnosed by expert physicians, completed a detailed interview comprehensive of: assessment of migraine characteristics; measure of physical activity (PA) levels; measure of the intake frequency of main Italian foods; the Insomnia Severity Index (ISI) questionnaire investigating sleep disorders. Results: We included 261 patients with a mean age of 44.5 ± 12.3 years. During social distancing, 72 patients (28%) reported a headache worsening, 86 (33%) an improvement, and 103 (39%) a stable headache frequency. A significant decrease of the PA levels during COVID-19 quarantine in the whole study sample was observed (median total metabolic equivalent task (METs) decreased from 1170 to 510; p < 0.001). Additionally, a significant difference was reported on median ISI scores (from 7 to 8; p < 0.001), which were increased in patients who presented a stable or worsening headache. Conclusions: Our study confirmed that the restrictions taken during the pandemic have affected the practice of PA levels and sleep quality in migraine. Hence, PA and sleep quality should be assessed to find strategies for an improvement in quality of life. 相似文献
15.
Kyohei Itamura Arthur Wu Elisa Illing Jonathan Ting Thomas Higgins 《JMIR Public Health and Surveillance》2021,7(1)
BackgroundReal-time polymerase chain reaction using nasopharyngeal swabs is currently the most widely used diagnostic test for SARS-CoV-2 detection. However, false negatives and the sensitivity of this mode of testing have posed challenges in the accurate estimation of the prevalence of SARS-CoV-2 infection rates.ObjectiveThe purpose of this study was to evaluate whether technical and, therefore, correctable errors were being made with regard to nasopharyngeal swab procedures.MethodsWe searched a web-based video database (YouTube) for videos demonstrating SARS-CoV-2 nasopharyngeal swab tests, posted from January 1 to May 15, 2020. Videos were rated by 3 blinded rhinologists for accuracy of swab angle and depth. The overall score for swab angle and swab depth for each nasopharyngeal swab demonstration video was determined based on the majority score with agreement between at least 2 of the 3 reviewers. We then comparatively evaluated video data collected from YouTube videos demonstrating the correct nasopharyngeal swab technique with data from videos demonstrating an incorrect nasopharyngeal swab technique. Multiple linear regression analysis with statistical significance set at P=.05 was performed to determine video data variables associated with the correct nasopharyngeal swab technique.ResultsIn all, 126 videos met the study inclusion and exclusion criteria. Of these, 52.3% (66/126) of all videos demonstrated the correct swab angle, and 46% (58/126) of the videos demonstrated an appropriate swab depth. Moreover, 45.2% (57/126) of the videos demonstrated both correct nasopharyngeal swab angle and appropriate depth, whereas 46.8% (59/126) of the videos demonstrated both incorrect nasopharyngeal swab angle and inappropriate depth. Videos with correct nasopharyngeal swab technique were associated with the swab operators identifying themselves as a medical professional or as an Ear, Nose, Throat–related medical professional. We also found an association between correct nasopharyngeal swab techniques and recency of video publication date (relative to May 15, 2020).ConclusionsOur findings show that over half of the videos documenting the nasopharyngeal swab test showed an incorrect technique, which could elevate false-negative test rates. Therefore, greater attention needs to be provided toward educating frontline health care workers who routinely perform nasopharyngeal swab procedures. 相似文献
16.
Andrea Calcagno Valeria Ghisetti Teresa Emanuele Mattia Trunfio Silvia Faraoni Lucio Boglione Elisa Burdino Sabrina Audagnotto Filippo Lipani Marco Nigra Antonio DAvolio Stefano Bonora Giovanni Di Perri 《Emerging infectious diseases》2021,27(1):303
We measured severe acute respiratory syndrome coronavirus 2 spike protein subunits S1/S2 antibodies by using capillary electrophoresis and a chemiluminescence immunoassay for 5,444 active healthcare workers in Italy. Seroprevalence was 6.9% and higher among participants having contact with patients. Seroconversion was not observed in 37/213 previously infected participants. 相似文献
17.
18.
Gordon Nicole T. Alberty-Oller Jaime J. Fei Kezhen Greco Giampaolo Gallagher Emily J. LeRoith Derek Feldman Sheldon M. Killilea Bridgid Boolbol Susan K. Choi Lydia Friedman Neil Pilewskie Melissa Port Elisa Tiersten Amy Bickell Nina A. 《Annals of surgical oncology》2021,28(11):5941-5947
Annals of Surgical Oncology - Black women with breast cancer have a worse overall survival compared with White women; however, no difference in Oncotype DX? (ODX) recurrence scores has been... 相似文献
19.
Archives of Sexual Behavior - 相似文献
20.
Antonella Massari Massimo Gennarelli Elisa Menegazzo Antonio Pizzuti Vincenzo Silani Ismaele Mastrogiacomo Enzo Pagani Corrado Angelini Guglielmo Scarlato Giuseppe Novelli Bruno Dallapiccola 《Journal of neurology》1995,242(6):379-383
We have analysed the [AGC] expansion in leucocytes, muscle and sperm from 17 individuals affected by myotonic dystrophy (DM). Skeletal muscle showed a larger repeat number than leucocytes in the same patient. A similar degree of expansion was detected in differently affected muscles of a single patient. The germline mutation ( 350 repeats) was expanded in somatic cells of the progeny in all patients examined. Our results provide evidence of an early postzygotic instability of the [AGC] repeat in DM. 相似文献