全文获取类型
收费全文 | 35881篇 |
免费 | 2371篇 |
国内免费 | 217篇 |
专业分类
耳鼻咽喉 | 323篇 |
儿科学 | 1050篇 |
妇产科学 | 886篇 |
基础医学 | 5502篇 |
口腔科学 | 563篇 |
临床医学 | 3036篇 |
内科学 | 8968篇 |
皮肤病学 | 967篇 |
神经病学 | 3837篇 |
特种医学 | 754篇 |
外科学 | 3186篇 |
综合类 | 115篇 |
一般理论 | 18篇 |
预防医学 | 2902篇 |
眼科学 | 702篇 |
药学 | 2602篇 |
中国医学 | 94篇 |
肿瘤学 | 2964篇 |
出版年
2024年 | 54篇 |
2023年 | 457篇 |
2022年 | 1103篇 |
2021年 | 1785篇 |
2020年 | 874篇 |
2019年 | 1344篇 |
2018年 | 1435篇 |
2017年 | 996篇 |
2016年 | 1147篇 |
2015年 | 1278篇 |
2014年 | 1685篇 |
2013年 | 2050篇 |
2012年 | 3029篇 |
2011年 | 3085篇 |
2010年 | 1752篇 |
2009年 | 1498篇 |
2008年 | 2324篇 |
2007年 | 2332篇 |
2006年 | 2126篇 |
2005年 | 1949篇 |
2004年 | 1640篇 |
2003年 | 1487篇 |
2002年 | 1294篇 |
2001年 | 151篇 |
2000年 | 92篇 |
1999年 | 177篇 |
1998年 | 233篇 |
1997年 | 185篇 |
1996年 | 127篇 |
1995年 | 109篇 |
1994年 | 80篇 |
1993年 | 70篇 |
1992年 | 54篇 |
1991年 | 38篇 |
1990年 | 36篇 |
1989年 | 28篇 |
1988年 | 26篇 |
1987年 | 25篇 |
1986年 | 28篇 |
1985年 | 22篇 |
1984年 | 15篇 |
1983年 | 27篇 |
1982年 | 21篇 |
1981年 | 22篇 |
1980年 | 24篇 |
1978年 | 10篇 |
1977年 | 15篇 |
1975年 | 12篇 |
1974年 | 16篇 |
1971年 | 12篇 |
排序方式: 共有10000条查询结果,搜索用时 218 毫秒
81.
Delvys Rodríguez-Abreu Marta Llanos Muñoz Mariano Provencio Pulla Antonio Rueda Domínguez Dolores Isla Casado 《Clinical & translational oncology》2010,12(11):760-764
Follicular lymphoma (FL) is the second most common subtype of non-Hodgkin’s lymphoma (NHL) in the Western world. FL constitutes the most frequent indolent lymphoma, well characterized by its clinical presentation related to nodal involvement and its morphologic and biologic features. It is often managed as an incurable disease. However, several active therapeutic approaches from the ‘wait and watch” strategy to the allogeneic transplantation are available for management of patients with FL and clearly have changed the natural history of this disease, achieving a long-term disease-free survival. Therapeutic decision is mostly conditioned by patient’s characteristics, stage, histological grade, tumor burden, and risk-predicting factors. This article try to summarizes the diagnosis and treatment of this heterogeneous group of patients. 相似文献
82.
Adriano Chiò Elena Herrero Hernandez Gabriele Mora Consuelo Valentini Gianluigi Discalzi Enrico Pira 《Amyotrophic lateral sclerosis and other motor neuron disorders》2004,5(3):188-191
A 34-years-old floor-layer developed optic neuropathy and motor neuron disease after being accidentally exposed to a solvent mixture containing methanol and other substances. Optic neuropathy is a complication of methanol poisoning, but the onset of a motor neuron disorder resembling amyotrophic lateral sclerosis after the exposure to these substances has not been previously described. The temporal onset of the clinical symptoms, biological plausibility, young age of the patient and absence of neurological disorders in the family history raises suspicion of a possible causative relationship. 相似文献
83.
Marta Feldmesser 《Medical mycology》2005,43(7):571-587
Invasive aspergillosis is a disease of immunocompromised hosts and the pathogenesis of this disorder is heavily dependent upon the defect within a given host. Consequently, vaccine development is limited by our understanding of effective host responses and by limitations in our knowledge of fungal molecules that elicit protective immunity. Nonetheless, the past few years have witnessed advances in our understanding both of the immune response to this organism and in the relationship between antigenicity and the ability to confer protection. Manipulations that promote the development of T(H)1-associated responses correlate with increased resistance to disease, at least partly because of consequent enhancement of innate cellular effector function. Two areas of investigation most actively being pursued include the search for adjuvants that will allow products of Aspergillus fumigatus to become effective vaccine candidates, regardless of the form of immunity they ordinarily induce, and the identification of the specific antigens that will most effectively elicit beneficial responses. Strategies using antigen-exposed dendritic cells as adjuvants appear to be particularly promising. Though we currently are far away from a candidate that is applicable for human trials, recent progress is encouraging. 相似文献
84.
Homid Fahandezh-Saddi Díaz Antonio Ríos-Luna Eduardo García-Rey Ma Jesus Rodea Butragueño Manuel Villanueva-Martinez Ma Elena Cantero-Yubero Miguel del Cerro-Gutiérrez 《European journal of orthopaedic surgery & traumatology : orthopedie traumatologie》2007,17(1):105-109
Treatment of chronic osteomyelitis of distal tibia is complex. It often requires the association of antibiotic therapy and a surgical procedure. This consists of exhaustive debridement of infected bone and soft tissue which must have adequate cutaneous coverage and vascular supply which enables creating a barrier to microorganisms and greater resistance to infection. Free or pedicled muscular flaps have been the techniques most often used for this type of lesions. Free flaps require a precise microsurgical technique and prolonged surgery. Pedicled muscular flaps do not provide sufficient coverage and vascularisation of the distal tibia for large size defects. The fasciocutaneous flap has been used for the treatment of coverage defects in the perimalleolar area and the heel. We report the utility of this flap as management of chronic osteomyelitis of the distal third of the tibia with complete healing of the infection and correct cutaneous coverage without complications. 相似文献
85.
Angela Favaro Tatiana Zanetti Elena Tenconi Daniela Degortes Andrea Ronzan Angela Veronese Paolo Santonastaso 《Eating disorders》2004,13(1):61-70
To date, few studies have examined the personality characteristics and clinical predictors of impulsive behaviors in eating disorders (ED). The aim of this work was to study the prevalence of a wide range of impulsive behaviors in a sample of 554 ED subjects and to examine the predictors of these behaviors. Subjects were diagnosed according to DSM-IV criteria as having anorexia nervosa restricting type (ANR; n = 183), anorexia nervosa binge eating/purging type (ANBP; n = 65), bulimia nervosa purging type (BNP; n = 244), and bulimia nervosa nonpurging type (BNNP; n = 62). Nine different types of impulsive behaviors were assessed in these groups. About 55% of the whole sample reported at least one type of impulsive behavior, 35% more than one, and about 13% more than three. According to findings, impulsive and multi-impulsive subjects are characterized by the presence of purging behavior and by specific temperamental features such as high levels of novelty seeking and low persistence. The prediction of impulsive behavior is further improved by considering the presence of a history of childhood abuse, maternal psychiatric morbidity, and some specific psychological symptoms such as maturity fears, perfectionism, depression, and obsessive-compulsive symptoms. The presence of impulsive behavior appears to be associated with overall higher levels of psychiatric symptomatology and eating psychopathology, thus indicating that they are an important feature to be considered in the assessment and treatment of ED. 相似文献
86.
87.
88.
Daniel Hryhorczuk Irina Dardynskaia Elena Lukyanova Marta Matwyshyn-Fuoco Lee Friedman Zoreslava Shkiryak-Nizhnyk Alexander Zvinchuk Natalia Chislovska Yuri Antipkin 《Paediatric and perinatal epidemiology》2009,23(4):346-351
The prevalence of wheezing in children varies widely around the world. The reasons for this geographic variability remain unclear but may be related in part to exposures in the home environment during pregnancy and early childhood. We investigated the prenatal and early childhood risk factors for wheezing symptoms among 2127 children aged 6–8 years who were participants in the Ukrainian component of the European Longitudinal Study of Pregnancy and Childhood (ELSPAC). Cases included the 169 children whose parents answered yes to the International Study of Asthma and Allergy in Children (ISAAC) question: 'Has your child had wheezing or whistling in the chest in the past 12 months' during the ELSPAC assessment of the children at age 7. These were compared with the 1861 children in the cohort whose parents answered 'no' to this question.
Factors significantly associated with increased risk of wheezing illness at age 7 in adjusted analyses included mother's asthma [adjusted odds ratio (OR) 3.46, 95% confidence interval (CI) 1.22, 9.85]; mother's allergy problems (OR 1.43, [1.00, 2.05]); rarely playing with other children at age 3 (OR 1.84, [1.09, 3.11]); water intrusion (OR 1.62, [1.09, 2.39]) and inadequate heating of the home (OR 1.52, [1.06, 2.16]) during pregnancy. Factors protective of wheezing at age 7 included being first-born (adjusted OR 0.70, 95% CI 0.50, 0.98); living in the city of Dniprodzerzynsk as compared with Kyiv (OR 0.36, [0.24, 0.54]) and weekly contact with furry animals (OR 0.44, [0.20, 0.97]) before age 3. The constellation of risk factors for wheezing in Ukrainian children is similar to that of children in other parts of the world. Known risk factors do not account for the significant between-city variability of wheezing in Ukrainian children. 相似文献
Factors significantly associated with increased risk of wheezing illness at age 7 in adjusted analyses included mother's asthma [adjusted odds ratio (OR) 3.46, 95% confidence interval (CI) 1.22, 9.85]; mother's allergy problems (OR 1.43, [1.00, 2.05]); rarely playing with other children at age 3 (OR 1.84, [1.09, 3.11]); water intrusion (OR 1.62, [1.09, 2.39]) and inadequate heating of the home (OR 1.52, [1.06, 2.16]) during pregnancy. Factors protective of wheezing at age 7 included being first-born (adjusted OR 0.70, 95% CI 0.50, 0.98); living in the city of Dniprodzerzynsk as compared with Kyiv (OR 0.36, [0.24, 0.54]) and weekly contact with furry animals (OR 0.44, [0.20, 0.97]) before age 3. The constellation of risk factors for wheezing in Ukrainian children is similar to that of children in other parts of the world. Known risk factors do not account for the significant between-city variability of wheezing in Ukrainian children. 相似文献
89.
90.