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951.
952.
Effectiveness of long-term beta-blocker therapy for dilated cardiomyopathy—echocardiographical follow-up 总被引:1,自引:0,他引:1
Masatake Fukunami Kazuhiko Hashimura Masaharu Ohmori Toshitaro Ikeda Kiyoshi Umemoto Kazuaki Kumagai Akihiko Sakai Takahisa Yantada Nobuhiko Kondoh Tetsuo Minamino Tomofumi Nagareda Kiyoshi Kotoh Noritake Hoki 《Cardiovascular drugs and therapy / sponsored by the International Society of Cardiovascular Pharmacotherapy》1991,5(2):463-469
To evaluate the effectiveness of long-term beta-blocker therapy for dilated cardiomyopathy (DCM), two groups (Group I: 18 patients, Group II: 17 patients) with DCM divided by the order at the entry were followed echocardiographically for 16.9 +/- 3.0 months in Group I and 21.4 +/- 3.9 months in Group II. Metoprolol (final dose: 60 mg/day) was administered in Group I, but not in Group II (the control), although the conventional treatment for heart failure was continued. The left ventricular end-systolic dimension and ejection fraction assessed by echocardiography improved significantly after 6 months in Group I, but not in Group II, even after 48 months, although there were no significant differences in baseline data between the two groups. The end-diastolic dimension decreased significantly after 12 months in Group I only. It was estimated, using the point count method on a left ventricular endomyocardial biopsy specimen taken at entry, that the improvement (delta EF) of the ejection fraction 12 months after metoprolol administration inversely correlated (r = -0.677, p less than 0.01) with percent fibrosis, indicating that the more myocardium remains, the more improvement is expected. These findings suggested a favorable effect of beta blockade in DCM, especially in cases with less fibrosis, showing that the endomyocardial biopsy could be of clinical use in selecting candidates for chronic beta-blocker therapy in DCM. 相似文献
953.
954.
Elevation of the Serum Fas Ligand in Patients With Hemophagocytic Syndrome and Diamond-Blackfan Anemia 总被引:8,自引:1,他引:8
955.
Tsujioka Y Jinzaki M Tanimoto A Nakagawa K Akita H Kikuchi E Okuda S Mikami S Oya M Kuribayashi S 《Journal of magnetic resonance imaging : JMRI》2012,35(2):431-435
Localized amyloidosis is a rare condition, especially that involving the ureter. Because of its rarity and the difficulty in differentiating this condition from urothelial carcinoma by intravenous urography and computed tomography, nephroureterectomy has often been performed unnecessarily for this disease. The authors encountered two cases of this disease, both of which showed a negative urine cytology, no obvious mass effect, and a hypointensity on T2-weighted imaging. Because these findings are very rare in urothelial carcinoma, ureteroscopy-guided biopsy was performed, which yielded the diagnosis of amyloidosis. The patients were then treated and followed up at our institute. Primary localized amyloidosis of the ureter should be considered when evaluating ureteric lesions visualized as hypointensities on T2-weighted images that do not show an obvious mass effect, which could help in the avoidance of unnecessary surgery. 相似文献
956.
Kondo A Date I Endo S Fujii K Fujii Y Fujimaki T Hasegawa M Hatayama T Hongo K Inoue T Ishikawa M Ito M Kayama T Kohmura E Matsushima T Munemoto S Nagahiro S Ohno K Okamura T Ryu H Shigeno T Shirane R Tagusagawa Y Tanabe H Yamada K Yamakami I 《Acta neurochirurgica》2012,154(5):773-778
Background
The purpose of this study was to evaluate and analyze overall postoperative results from microvascular decompression (MVD) by combining the cure rate of symptoms with the complication rate. A new scoring system for obtaining objective surgical results from MVD for trigeminal neuralgia (TN) and hemifacial spasm (HFS) is proposed to document treatment results using consistent criteria in a standardized manner.Method
Surgical results combining complications , if any, were obtained from a questionnaire sent to patients who had undergone surgery for TN or HFS in recent years and had been followed-up for more than 1?year after surgery (TN patients, n?=?54; HFS patients, n?=?81) When surgical outcome is complete resolution of symptoms, the efficacy of surgery (E) is designated E-0, but when moderate symptoms are still persist postoperatively, the score is designated E-2. When no complications are seen after surgery, the complication score (C) is C-0, while the score is C-2 if troublesome complications remain. In addition, total evaluation of the results (T) is judged by combining the E and C scores. For example, when E is 0, and C is C-2, the total evaluation is scored as T-2, which is diagnosed as fair.Findings
The response rate of the questionnaire was 80.7% (109/135). Overall surgical data were evaluated and analyzed using our new scoring system. Analysis of the collected data revealed an outcome of T-0 was 70% (35/50 patients) and T-1 was 24% (12/50) and T-2 was 6% (3/50) in TN, whereas in HFS, T-0 was 61% (36/59) and T-1 was 27.1% (16/59) and T-2 was 6.8% (4/59) and T-3 was 5.1% (3/59).Conclusion
The total results of MVD should be evaluated and analyzed by combining the cure rate of symptoms together with the complication rate. This new scoring system could allow much more objective analysis of the results of following MVD. Adopting this scoring system to objectively judge treatment results for TN and HFS, individual surgeons can compare their own overall surgical results with those of other institutes. Comparative results of MVD can also be provided to patients considering therapy to allow informed decision-making on the basis of good quality evidence. 相似文献957.
Bessho Y Sugai K Fuse A Hitomi E Sugai Y 《Masui. The Japanese journal of anesthesiology》2012,61(3):311-313
A 66-year-old man was injured in the traffic accident and showed the signs of hemorrhagic shock. His blood type was Rh negative O. As excessive bleeding was going on, we decided to transfuse 8 units of Rh-incompatible type O red blood cell (RBC) without performing cross match test according to the guideline for treatment of critical bleeding. Though we were aware of the risks of that treatment, no hemolytic reaction nor any other side effect was observed during and after the transfusion. Anti-Rh antibody was not developed either while Anti-Rh immunoglobulin was not given to him. His blood type has been proved to be Del type red blood cell. We conclude that transfusion of Rh-incompatible blood in patient with critical hemorrhage should be encouraged to save life. 相似文献
958.
Matsuda Y Yatsuyanagi E Sato K 《Kyobu geka. The Japanese journal of thoracic surgery》2012,65(9):808-811
We report a rare case of pulmonary squamous papilloma. A 42-year-old woman was referred to our hospital complaining of dry cough. A chest computed tomography (CT) showed a mass shadow in the lower lobe of left lung. Serum concentrations of carcinoembryonic antigen (CEA) and squamous cell carcinoma-related antigen (SCC) were elevated to 13.0 ng/ml and 11.8 ng/ml, respectively. The mass was positron emission tomography( PET)-positive, with a maximum standard uptake value( SUVmax) of 11.55, suggesting a malignant neoplasm. Under the guidance of video-assisted thoracoscopy, left basal segmentectomy was performed. Intra-operative diagnosis was a squamous papilloma and no malignancy. Her postoperative course was uneventful. She is currently alive without any sign of recurrence. 相似文献
959.
Spontaneous perforation of a choledochal cyst with ensuing pseudocyst formation is a very rare complication. We report the development of a pseudocyst adjacent to a choledochal cyst in a very low-birth-weight infant at 2 months of age. Elective excision of the choledochal cyst and biliary tract reconstruction were successfully performed 2 months later when the infant weighed 3 kg. Delayed primary repair may be a viable alternative treatment for low-birth-weight infants with choledochal cysts. 相似文献
960.
Yokoi A Arai H Bitoh Y Nakao M Oshima Y Nishijima E 《Journal of pediatric surgery》2012,47(6):1080-1083
PurposeCongenital tracheal stenosis is a rare condition and can be difficult to manage. One source of difficulty is postoperative tracheomalacia requiring long-term tracheal stenting. To prevent symptomatic postoperative tracheomalacia, we have been adding aortopexy to tracheal reconstruction since 2008. The aim of this study was to evaluate efficacy of aortopexy for preventing postoperative tracheomalacia after reconstruction of congenital tracheal stenosis.MethodsRetrospective chart review was conducted. From October 2003 to March 2011, 24 had tracheal reconstruction without aortopexy (group A) and 8 with aortopexy (group B). Statistical analysis was performed using Fisher's Exact test.ResultsOne had anastomotic leakage in group A, and 1, in group B (P = .44). Eleven patients required tracheostomy because of postoperative tracheomalacia confirmed by postoperative bronchoscopy in group A vs none in group B (P = .029).ConclusionsWe found that aortopexy with tracheal reconstruction reduced the need for postoperative tracheostomy in this patient group. Although there is a potential risk of anastomotic leakage because of the suspension suture on the anterior tracheal wall to aorta, we did not detect an increased incidence after aortopexy. Thus, aortic suspension may be a useful adjunct to prevent symptoms of tracheomalacia in these patients. 相似文献