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排序方式: 共有4157条查询结果,搜索用时 15 毫秒
101.
Guido Basilisco Giovanni Barbara Massimo Bellini Giovanni Cataudella Lucia D’Alba Michele Guarino Paola Iovino Maria Cristina Neri Giovanni Sarnelli Edoardo Savarino Salvatore Tolone Francesco Torresan Paolo Usai-Satta Ambra Lovati Elena Arsiè Marina Coletta 《Alimentary pharmacology & therapeutics》2020,51(9):910-911
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Aiello Edoardo Nicol Esposito Antonella Giannone Ilaria Diana Lorenzo Woolley Susan Murphy Jennifer Christodoulou Georgia Tremolizzo Lucio Bolognini Nadia Appollonio Ildebrando 《Neurological sciences》2022,43(4):2571-2578
Neurological Sciences - Up to 50% of motor neuron disease (MND) patients show neuropsychological deficits which negatively affect prognosis and care. However, disability-related logistical issues... 相似文献
104.
Aiello Edoardo Nicol Rimoldi Sara Bolognini Nadia Appollonio Ildebrando Arcara Giorgio 《Neurological sciences》2022,43(2):821-845
Neurological Sciences - Cognitive screening tests (CSTs) are crucial to neuropsychological diagnostics, and thus need to be featured by robust psychometric and diagnostic properties. However, CSTs... 相似文献
105.
Golfr Andreasi Nico Romito Luigi Michele Telese Roberta Cilia Roberto Elia Antonio Emanuele Novelli Alessio Tringali Giovanni Messina Giuseppe Levi Vincenzo Devigili Grazia Rinaldo Sara Franzini Angelo Amato Eleopra Roberto 《Neurological sciences》2022,43(3):1769-1781
Neurological Sciences - Subthalamic nucleus deep brain stimulation (STN-DBS) is an established treatment for patients with Parkinson’s disease (PD) with motor complications; the contribution... 相似文献
106.
Manera Marina Rita Fiabane Elena Pain Debora Aiello Edoardo Nicol Radici Alice Ottonello Marcella Padovani Mariacristina Wilson Barbara Ann Fish Jessica Pistarini Caterina 《Neurological sciences》2022,43(1):45-50
Neurological Sciences - The novel human coronavirus (SARS-CoV-2) shows neurotropism and systemically affects the central nervous system (CNS). Cognitive deficits have been indeed reported as both... 相似文献
107.
Aiello Edoardo Nicol Fiabane Elena Manera Marina Rita Radici Alice Grossi Federica Ottonello Marcella Vassallo Claudio Pain Debora Pistarini Caterina 《Neurological sciences》2022,43(2):785-788
Neurological Sciences - Episodic long-term memory (LTM) difficulties/deficits are frequent in COVID-19-recovered patients and negatively impact on prognosis and outcome. However, little is known... 相似文献
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Development and preliminary assessment of a robotic platform for neuroendoscopy based on a lightweight robot 下载免费PDF全文
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Human pancreatic secretory trypsin inhibitor stabilizes intestinal mucosa against noxious agents 下载免费PDF全文
Marchbank T Mahmood A Fitzgerald AJ Domin J Butler M Goodlad RA Elia G Cox HM van Heel DA Ghosh S Playford RJ 《The American journal of pathology》2007,171(5):1462-1473
Pancreatic secretory trypsin inhibitor (PSTI) is a serine protease inhibitor, expressed in gut mucosa, whose function is unclear. We, therefore, examined the effects of PSTI on gut stability and repair. Transgenic mice overexpressing human PSTI within the jejunum (FABPi(-1178 to +28) hPSTI construct) showed no change in baseline morphology or morphometry but reduced indomethacin-induced injury in overexpressing hPSTI region by 42% (P < 0.01). Systemic recombinant hPSTI did not affect baseline morphology or morphometry but truncated injurious effects in prevention and recovery rat models of dextran-sodium-sulfate-induced colitis. In vitro studies showed PSTI stimulated cell migration but not proliferation of human colonic carcinoma HT29 or immortalized mouse colonic YAMC cells. PSTI also induced changes in vectorial ion transport (short-circuit current) when added to basolateral but not apical surfaces of polarized monolayers of Colony-29 cells. Restitution and vectorial ion transport effects of PSTI were dependent on the presence of a functioning epidermal growth factor (EGF) receptor because cells with a disrupted (EGFR(-/-) immortalized cells) or neutralized (EGFR blocking antibodies or tyrosine kinase inhibitor) receptor prevented these effects. PSTI also reduced the cytokine release of lipopolysaccharide-stimulated dendritic cells. We conclude that administration of PSTI may provide a novel method of stabilizing intestinal mucosa against noxious agents and stimulating repair after injury. 相似文献