全文获取类型
收费全文 | 14932篇 |
免费 | 1518篇 |
国内免费 | 1126篇 |
专业分类
耳鼻咽喉 | 84篇 |
儿科学 | 179篇 |
妇产科学 | 131篇 |
基础医学 | 1700篇 |
口腔科学 | 336篇 |
临床医学 | 1958篇 |
内科学 | 2316篇 |
皮肤病学 | 162篇 |
神经病学 | 914篇 |
特种医学 | 523篇 |
外国民族医学 | 5篇 |
外科学 | 1695篇 |
综合类 | 2503篇 |
现状与发展 | 4篇 |
一般理论 | 1篇 |
预防医学 | 1023篇 |
眼科学 | 437篇 |
药学 | 1513篇 |
1篇 | |
中国医学 | 710篇 |
肿瘤学 | 1381篇 |
出版年
2024年 | 37篇 |
2023年 | 227篇 |
2022年 | 496篇 |
2021年 | 761篇 |
2020年 | 588篇 |
2019年 | 528篇 |
2018年 | 561篇 |
2017年 | 455篇 |
2016年 | 458篇 |
2015年 | 688篇 |
2014年 | 812篇 |
2013年 | 711篇 |
2012年 | 1011篇 |
2011年 | 1167篇 |
2010年 | 770篇 |
2009年 | 581篇 |
2008年 | 778篇 |
2007年 | 757篇 |
2006年 | 701篇 |
2005年 | 698篇 |
2004年 | 571篇 |
2003年 | 552篇 |
2002年 | 497篇 |
2001年 | 421篇 |
2000年 | 391篇 |
1999年 | 395篇 |
1998年 | 286篇 |
1997年 | 245篇 |
1996年 | 169篇 |
1995年 | 173篇 |
1994年 | 104篇 |
1993年 | 95篇 |
1992年 | 137篇 |
1991年 | 102篇 |
1990年 | 117篇 |
1989年 | 82篇 |
1988年 | 83篇 |
1987年 | 71篇 |
1986年 | 73篇 |
1985年 | 56篇 |
1984年 | 43篇 |
1983年 | 10篇 |
1982年 | 14篇 |
1981年 | 16篇 |
1980年 | 13篇 |
1979年 | 10篇 |
1978年 | 8篇 |
1975年 | 6篇 |
1974年 | 8篇 |
1973年 | 6篇 |
排序方式: 共有10000条查询结果,搜索用时 31 毫秒
61.
62.
Twenty-seven cases of metastatic tumor of posterior fossa were presented in this paper. Of the patients, 20 were males and 7 females; their age ranged from 20 to 68, and 89% of them were over 40 years of age. The primary foci found were bronchopulmonary carcinomas (7 cases), rhinopharyngeal carcinomas (3 cases), and cancer of the liver (1 case), but in 16 cases the primary foci were not found. All of these patients presented symptoms and signs of obviously increased intracranial pressure, and most of them had the signs of cerebellar and cranial nerves' lesions. Ventriculorgraphy and brain CT scanning were important procedures in the diagnosis, and MRI was most valuable in establishing the diagnosis and localization of posterior fossa metastatic tumors. Twenty-six patients underwent operation. The short-term follow-up study showed an improvement in 25 cases. There was one death. The surgical treatment of posterior fossa metastatic tumor was emphasized. Radiotherapy and chemotherapy were discussed. 相似文献
63.
Immunoreactivity to Fos protein (Fos-IR) was detected in rat hypothalamic neurons within 1 h of onset of hemorrhage by withdrawing 4-5 ml of blood, which lowered the arterial blood pressure to 50-70 mm Hg. About 70% of vasopressin (AVP)-containing neurons in the supraoptic nucleus (SON) and 20% in the paraventricular nucleus (PVN) expressed Fos-IR. In contrast, 5% of oxytocin (OXY)-containing neurons in the SON and < 1% in PVN were Fos-IR. Intravenous infusion of the vasodilating agent, nitroprusside, which lowered the blood pressure to levels comparable to that attained by hemorrhage, induced Fos-IR in greater than 65% of AVP-containing neurons in the SON, while relatively few AVP neurons in the PVN were Fos positive. These results suggest that hemorrhage or hypotension preferentially induces c-fos expression in supraoptic AVP-containing neurons. 相似文献
64.
65.
66.
67.
目的观察颈丛阻滞下行颈动脉内膜剥脱术的效果.方法 28名ASAⅡ~Ⅲ级患者行32例颈动脉内膜剥脱术,采用深浅丛联合阻滞,观察围术期血液动力学指标变化,分流管放置率和并发症情况.结果 麻醉后血压和心率与麻醉前相比差异有显著性(P<0.05),其它时点与麻醉前相比差异无显著性(P>0.05).颈动脉夹闭前后收缩压和心率的波动性的差异无显著性(P>0.05).围术期高血压的发生率为50.0%,低血压6.25%,心动过速28.1%,心动过缓6.25%,分流管放置率6.25%.患者满意率84.4%.无1例改用全麻,无严重围术期并发症.结论颈丛阻滞是颈动脉内膜剥脱术安全、有效的麻醉方法. 相似文献
68.
L. Cheng †‡ T. Enomoto§ T. Hirota† M. Shimizu † N. Takahashi† M. Akahoshi† A. Matsuda† Y. Dake§ S. Doi¶ K. Enomoto A. Yamasaki S. Fukuda X.-Q. Mao J. M. Hopkin M. Tamari† T. Shirakawa † 《Clinical and experimental allergy》2004,34(8):1192-1201
BACKGROUND: A recent report provided evidence that a disintegrin and metalloprotease domain 33 (ADAM33), a member of the ADAM family, is a novel susceptibility gene in asthma linked to bronchial hyper-responsiveness. However, there has been no investigation of the genetic role of ADAM33 variants in nasal allergy. OBJECTIVE: The purpose of this study was to test the association between ADAM33 polymorphisms and Japanese cedar pollinosis (JCPsis), a most common seasonal allergic rhinitis in Japan. METHODS: We conducted a case-control association study among a Japanese population, involving 95 adult individuals with JCPsis and 95 normal healthy controls. A total of 22 single-nucleotide polymorphisms (SNPs) in ADAM33 were genotyped using PCR-based molecular methods. RESULTS: Six SNPs of ADAM33 gene, three in introns (7575G/A, 9073G/A and 12540C/T) and three in the coding region (10918G/C, 12433T/C and 12462C/T), were strongly associated with JCPsis (P = 0.0002-0.022 for absolute allele frequencies) and most of the SNPs were in linkage disequilibrium with each other. A higher frequency of the common alleles of these SNPs was noted for the subjects with JCPsis in comparison with healthy controls. We also identified a haplotype associated with the disease susceptibility. In addition, associations were found between ADAM33 polymorphisms and various cedar pollinosis phenotypes including clinical severity, eosinophil counts in nasal secretion and allergen-specific IgE levels in sera, but not total serum IgE levels. CONCLUSION: These results indicate that polymorphisms in the ADAM33 gene are associated with susceptibility to allergic rhinitis due to Japanese cedar pollen, but the functional relationship still needs clarification. 相似文献
69.
目的 探讨新型颈椎前路融合器(SOLIS)在颈椎前路融合术中的应用效果.方法 对18例脊髓型颈椎病、12例颈椎间盘突出症采用颈椎前路减压融合术,小切口入路(3~4 cm),椎间盘及部分椎体后缘切除后保留椎体终板,植人带自体松质骨的SOLIS.以手术前后X线片及JOA评分评价疗效.结果 30例随访6~18个月,平均12.5个月.置人的SOLIS位置良好,无移动及脱出迹象;病变椎间隙高度恢复正常,未见椎间高度丢失;所有节段均于术后3~8个月骨性融合.术前JOA评分平均10.4分,术后平均14.9分,两者有统计学意义(P<0.01).结论 颈椎前路融合器SOLIS具有良好的生物相容性,手术创伤小,能有效地恢复颈椎高度,融合率高,融合后稳定性好,神经功能改善优良率高. 相似文献
70.
经阴道行良性卵巢囊肿剥离术195例报告 总被引:1,自引:0,他引:1
目的探讨经阴道行良性卵巢囊肿剥离术的临床实用价值.方法2001年1月2004年6月对有手术指征的良性卵巢囊肿195例实施阴式手术,并观察有关手术指标.结果经阴道完成手术190例,5例因盆腔广泛粘连中转开腹.手术时间45~83 min,平均50 min.术中出血30~90 ml,平均45 ml.术后排气时间4~24 h,平均8.5 h.术后病率18.4%(35/190).183例随访2周内恢复日常家务及工作者分别为72.1%(132/183)、48.1%(88/183).结论经阴道行良性卵巢囊肿剥离术是一种安全、微创的手术. 相似文献