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81.
Seventy-four patients with impaired renal function were investigated by ultrasound. By assessing renal length, renal echogenicity and collecting system dilatation, one can establish whether renal function is impaired by chronic or acute renal changes or by obstructive changes.  相似文献   
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Ultrasensitive bright field in situ hybridization assays using enzyme metallography (EnzMet) have been developed and validated, but little is known regarding the applicability of EnzMet for immunophenotypic detection of protein via IHC. Superior resolution via discrete metallographic deposits offers the potential for enhancing high-resolution immunophenotyping. Using high-complexity tissue microarrays (TMAs), 88 common solid tumors were evaluated by automated EnzMet (Nanoprobes and Ventana). Targets were chosen to assess the ability of EnzMet to specifically localize encoded antigens in the nucleus (estrogen receptor), cytoplasm (cytokeratins), and cytoplasmic membrane (HER2) in TMAs. Results were compared with conventional IHC diaminobenzidine (DAB) immunostaining. There was full concordance between the EnzMet and conventional IHC results. Furthermore, the EnzMet reaction products did not appreciably diffuse, were dense and sharply defined, and provided excellent high-resolution differentiation of cellular compartments in paraffin sections for the nuclear, cytoplasmic, and cell membrane-localized antigens evaluated. The higher density of elemental silver deposited during enzyme metallography permitted evaluation of core immunophenotypes at a relatively low magnification, allowing more tissue to be screened in an efficient manner. This preliminary study shows the utility of using enzyme metallography for high-resolution immunophenotyping in TMAs.  相似文献   
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Alcohol and other drug (AOD) use behaviors of health professions students (HPS) were assessed by surveying both university-based HPS and other nursing programs in a Midwestern state in 1999. Response was 2,646 (56.4%) of surveyed students. Family history of alcohol-related and drug-related problems were reported by 39.8% and 13.9%, respectively, with 42.6% of respondents reporting one or both. Among nursing respondents, 48.1%, 19.2% and 51.1%, respectively, reported family problems with alcohol, drugs, or one or both. Past-year alcohol use was comparable to undergraduate college students (UCS) nationally (83%); heavy drinking, tobacco and recreational drug use by HPS were lower. Past year drug use was highest among medical students. Marijuana was the predominant illicit drug; medical students and males most often reported use. Health professions educational systems should proactively address student AOD prevention, education and assistance needs.  相似文献   
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Thomas Attig 《Death Studies》1991,15(4):385-393
Concepts of the grieving process as passive are rejected, and concepts of the process as active are embraced. Standard stage-phase and medical treatments of bereavement are based on the belief that grieving is experienced passively. The emotion of grief and the coping process of grieving are distinguished; the emotion is said to render the bereaved passive and the coping process is said to challenge the bereaved, presenting them with choices. Alternative concepts of the grieving process as an active one are reviewed, tasks that confront the bereaved are outlined, and grieving is discussed as being rich in choice. The importance of the latter concepts for promoting self-understanding and defining helping strategies is underscored.  相似文献   
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Mielke  H.  Daniel  W.  Deicher  H.  Drommer  W.  Fischer  M.  Fritsch  R.  M&#;ller-Vahl  H.  Sybrecht  G. W. 《Clinical rheumatology》1987,6(2):26-34
Clinical Rheumatology - Rheumatoid arthritis (RA) as a systemic disease can attack many other organs in addition to the joints. A variety of pathological lesions of the blood vessels are...  相似文献   
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