全文获取类型
收费全文 | 1623篇 |
免费 | 178篇 |
国内免费 | 14篇 |
专业分类
耳鼻咽喉 | 22篇 |
儿科学 | 92篇 |
妇产科学 | 30篇 |
基础医学 | 148篇 |
口腔科学 | 38篇 |
临床医学 | 267篇 |
内科学 | 254篇 |
皮肤病学 | 32篇 |
神经病学 | 119篇 |
特种医学 | 38篇 |
外科学 | 312篇 |
综合类 | 63篇 |
一般理论 | 1篇 |
预防医学 | 155篇 |
眼科学 | 14篇 |
药学 | 123篇 |
中国医学 | 1篇 |
肿瘤学 | 106篇 |
出版年
2021年 | 14篇 |
2020年 | 11篇 |
2019年 | 22篇 |
2018年 | 27篇 |
2017年 | 14篇 |
2016年 | 14篇 |
2015年 | 12篇 |
2014年 | 35篇 |
2013年 | 40篇 |
2012年 | 54篇 |
2011年 | 63篇 |
2010年 | 37篇 |
2009年 | 34篇 |
2008年 | 63篇 |
2007年 | 73篇 |
2006年 | 77篇 |
2005年 | 85篇 |
2004年 | 59篇 |
2003年 | 62篇 |
2002年 | 67篇 |
2001年 | 52篇 |
2000年 | 60篇 |
1999年 | 56篇 |
1998年 | 30篇 |
1997年 | 32篇 |
1996年 | 37篇 |
1995年 | 39篇 |
1994年 | 29篇 |
1993年 | 35篇 |
1992年 | 50篇 |
1991年 | 44篇 |
1990年 | 31篇 |
1989年 | 43篇 |
1988年 | 38篇 |
1987年 | 31篇 |
1986年 | 35篇 |
1985年 | 23篇 |
1984年 | 19篇 |
1983年 | 17篇 |
1982年 | 12篇 |
1981年 | 11篇 |
1980年 | 12篇 |
1979年 | 13篇 |
1974年 | 22篇 |
1973年 | 10篇 |
1972年 | 14篇 |
1971年 | 13篇 |
1970年 | 18篇 |
1968年 | 11篇 |
1966年 | 11篇 |
排序方式: 共有1815条查询结果,搜索用时 15 毫秒
991.
992.
993.
994.
Propranolol in the treatment of infantile haemangiomas: lessons from the European Propranolol In the Treatment of Complicated Haemangiomas (PITCH) Taskforce survey
下载免费PDF全文
![点击此处可从《The British journal of dermatology》网站下载免费的PDF全文](/ch/ext_images/free.gif)
E. Wedgeworth M. Glover A.D. Irvine I. Neri E. Baselga T.H. Clayton P.E. Beattie J.V. Bjerre N.P. Burrows R. Foelster‐Holst L. Hedelund A. Hernandez‐Martin H. Audrain K. Bhate S.J. Brown S. Baryschpolec S. Darne A. Durack V. Dvorakova J. Gach N. Goldstraw H. Goodyear S. Grabczynska D. Greenblatt J. Halpern R.M.R. Hearn S. Hoey B. Hughes R. Jayaraj E.K. Johansson M. Lam S. Leech G.M. O'Regan D. Morrison W. Porter R. Ramesh T. Schill L. Shaw A.E.M. Taylor R. Taylor J. Thomson P. Tiffin M. Tsakok S.R. Janmohamed B. Laguda T. McPherson A.P. Oranje A. Patrizi J.C. Ravenscroft H. Shahidullah L. Solman A. Svensson C.F. Wahlgren P.H. Hoeger C. Flohr 《The British journal of dermatology》2016,174(3):594-601
995.
996.
997.
ALPM Catelani ACV Krepischi CA Kim F Kok PA Otto MTBM Auricchio JF Mazzeu DT Uehara SS Costa J Knijnenburg A Tabith Jr AM Vianna-Morgante RC Mingroni-Netto C Rosenberg 《Clinical genetics》2009,76(5):458-464
The cause of hearing impairment has not been elucidated in a large proportion of patients. We screened by 1-Mb array-based comparative genomic hybridization (aCGH) 29 individuals with syndromic hearing impairment whose clinical features were not typical of known disorders. Rare chromosomal copy number changes were detected in eight patients, four de novo imbalances and four inherited from a normal parent. The de novo alterations define candidate chromosome segments likely to harbor dosage-sensitive genes related to hearing impairment, namely 1q23.3–q25.2, 2q22q23, 6p25.3 and 11q13.2–q13.4. The rare imbalances also present in normal parents might be casually associated with hearing impairment, but its role as a predisposition gene remains a possibility. Our results show that syndromic deafness is frequently associated with chromosome microimbalances (14–27%), and the use of aCGH for defining disease etiology is recommended. 相似文献
998.
999.
Anna DT Muntingh M Christina van der Feltz-Cornelis Harm WJ van Marwijk Philip Spinhoven Willem JJ Assendelft Margot WM de Waal Leona Hakkaart-van Roijen Herman J Adèr Anton JLM van Balkom 《BMC health services research》2009,9(1):159
Background
Panic disorder (PD) and generalized anxiety disorder (GAD) are two of the most disabling and costly anxiety disorders seen in primary care. However, treatment quality of these disorders in primary care generally falls beneath the standard of international guidelines. Collaborative stepped care is recommended for improving treatment of anxiety disorders, but cost-effectiveness of such an intervention has not yet been assessed in primary care. This article describes the aims and design of a study that is currently underway. The aim of this study is to evaluate effects and costs of a collaborative stepped care approach in the primary care setting for patients with PD and GAD compared with care as usual. 相似文献1000.
Conflicting selective forces affect T cell receptor contacts in an immunodominant human immunodeficiency virus epitope 总被引:2,自引:0,他引:2
Iversen AK Stewart-Jones G Learn GH Christie N Sylvester-Hviid C Armitage AE Kaul R Beattie T Lee JK Li Y Chotiyarnwong P Dong T Xu X Luscher MA MacDonald K Ullum H Klarlund-Pedersen B Skinhøj P Fugger L Buus S Mullins JI Jones EY van der Merwe PA McMichael AJ 《Nature immunology》2006,7(2):179-189
Cytotoxic T lymphocytes (CTLs) are critical for the control of human immunodeficiency virus, but containment of virus replication can be undermined by mutations in CTL epitopes that lead to virus escape. We analyzed the evolution in vivo of an immunodominant, HLA-A2-restricted CTL epitope and found two principal, diametrically opposed evolutionary pathways that exclusively affect T cell-receptor contact residues. One pathway was characterized by acquisition of CTL escape mutations and the other by selection for wild-type amino acids. The pattern of CTL responses to epitope variants shaped which variant(s) prevailed in the virus population. The pathways notably influenced the amount of plasma virus, as patients with efficient CTL selection had lower plasma viral loads than did patients without efficient selection. Thus, viral escape from CTL responses does not necessarily correlate with disease progression. 相似文献