全文获取类型
收费全文 | 330344篇 |
免费 | 63126篇 |
国内免费 | 14424篇 |
专业分类
耳鼻咽喉 | 3922篇 |
儿科学 | 7482篇 |
妇产科学 | 5883篇 |
基础医学 | 46094篇 |
口腔科学 | 9626篇 |
临床医学 | 44019篇 |
内科学 | 64341篇 |
皮肤病学 | 10436篇 |
神经病学 | 27357篇 |
特种医学 | 11980篇 |
外国民族医学 | 96篇 |
外科学 | 42515篇 |
综合类 | 34195篇 |
现状与发展 | 48篇 |
一般理论 | 77篇 |
预防医学 | 19544篇 |
眼科学 | 8433篇 |
药学 | 31076篇 |
165篇 | |
中国医学 | 12012篇 |
肿瘤学 | 28593篇 |
出版年
2024年 | 577篇 |
2023年 | 3232篇 |
2022年 | 7513篇 |
2021年 | 13062篇 |
2020年 | 13207篇 |
2019年 | 17918篇 |
2018年 | 17858篇 |
2017年 | 17985篇 |
2016年 | 18448篇 |
2015年 | 21882篇 |
2014年 | 24615篇 |
2013年 | 24420篇 |
2012年 | 23112篇 |
2011年 | 24676篇 |
2010年 | 20951篇 |
2009年 | 15196篇 |
2008年 | 16007篇 |
2007年 | 14948篇 |
2006年 | 14427篇 |
2005年 | 14243篇 |
2004年 | 10290篇 |
2003年 | 9214篇 |
2002年 | 8143篇 |
2001年 | 7436篇 |
2000年 | 7470篇 |
1999年 | 7218篇 |
1998年 | 3858篇 |
1997年 | 3854篇 |
1996年 | 2969篇 |
1995年 | 2742篇 |
1994年 | 2381篇 |
1993年 | 1613篇 |
1992年 | 2548篇 |
1991年 | 2190篇 |
1990年 | 1843篇 |
1989年 | 1624篇 |
1988年 | 1413篇 |
1987年 | 1260篇 |
1986年 | 1039篇 |
1985年 | 822篇 |
1984年 | 575篇 |
1983年 | 437篇 |
1982年 | 283篇 |
1981年 | 247篇 |
1980年 | 237篇 |
1979年 | 308篇 |
1978年 | 188篇 |
1977年 | 160篇 |
1976年 | 134篇 |
1974年 | 162篇 |
排序方式: 共有10000条查询结果,搜索用时 15 毫秒
21.
Evelyne Harkemanne Jean‐Louis Dargent Pierre‐Paul Roquet‐Gravy Audrey Bulinckx 《Pediatric dermatology》2019,36(3):365-367
We report a case of benign lymphoplasmacytic plaque (LPP) in a child. These asymptomatic erythematous papulonodular lesions are an emerging clinicopathological entity. Herein, we describe a previously unreported site for LPP lesions, namely, the volar wrist and the distal ipsilateral palm. 相似文献
22.
23.
目的:探索以系统化、标准化的新型冠状病毒核酸检测为核心和重要组成部分,建立适合于眼科医院新冠疫情精准防控切实可行的防控体系。方法:系列病例研究。自2020年2月24日至3月2日期间,以标准化病毒核酸检测联合血常规、C反应蛋白(CRP)、血清淀粉样蛋白A(SAA)等检测作为所有眼科手术患者术前筛查常规检测项目,同时也为返岗员工提供病毒核酸检测。设计调查问卷了解受检者对鼻咽拭子采样的接受度以及核酸检测结果对其心理状态的影响。结果:99例患者血液学检测结果有一定的异常比例,其中SAA检测结果增高13例,淋巴细胞计数减低12例、增高5例,白细胞计数增高11例、减低1例,CRP增高2例,新型冠状病毒核酸检测均阴性。33例本院职工新型冠状病毒核酸检测均阴性。12%的受访者对鼻咽拭子采样接受度评分较低。受检者在核酸检测前后思想压力评分较高的比例分别为46.7%和6.7%。结论:该项举措一方面为术前新冠病毒肺炎筛查及鉴别诊断提供了客观依据,很大程度上排除了隐性无症状感染者传播的可能,有利于减少二次传播的风险,降低院内交叉感染的概率;另一方面,核酸检测阴性结果有利于调整患者术前的心理状态并缓解医护人员在疫情防控期间的心理压力。 相似文献
24.
25.
Julie Despres Yasmina Ramdani Marine di Giovanni Magalie Bnard Abderrakib Zahid Mait Montero‐Hadjadje Florent Yvergnaux Thibaut Saguet Azeddine Driouich Marie‐Laure Follet‐Gueye 《Experimental dermatology》2019,28(8):922-932
It is well recognized that the world population is ageing rapidly. Therefore, it is important to understand ageing processes at the cellular and molecular levels to predict the onset of age‐related diseases and prevent them. Recent research has focused on the identification of ageing biomarkers, including those associated with the properties of the Golgi apparatus. In this context, Golgi‐mediated glycosylation of proteins has been well characterized. Additionally, other studies show that the secretion of many compounds, including pro‐inflammatory cytokines and extracellular matrix–degrading enzymes, is modified during ageing, resulting in physical and functional skin degradation. Since the Golgi apparatus is a central organelle of the secretory pathway, we investigated its structural organization in senescent primary human dermal fibroblasts using confocal and electron microscopy. In addition, we monitored the expression of Golgi‐related genes in the same cells. Our data showed a marked alteration in the Golgi morphology during replicative senescence. In contrast to its small and compact structure in non‐senescent cells, the Golgi apparatus exhibited a large and expanded morphology in senescent fibroblasts. Our data also demonstrated that the expression of many genes related to Golgi structural integrity and function was significantly modified in senescent cells, suggesting a relationship between Golgi apparatus function and ageing. 相似文献
26.
Jakub Pazdrowski Aleksandra Daczak‐Pazdrowska Adriana Polaska Joanna Ka
mierska Wojciech Barczak Mateusz Szewczyk Pawe Golusiski Zygmunt Adamski Ryszard aba Wojciech Golusiski 《Skin research and technology》2019,25(6):857-861
Radiodermatitis is one of the commonest side effects of radiotherapy. They are usually assessed by semi‐quantitative clinical scores, which are not validated and may be subject to inter‐observer variability. A few previous studies suggested that high‐frequency ultrasonography (HF‐USG) is useful in the assessment of the acute phase of radiation dermatitis in breast cancer patients. (a) To monitor skin changes by HF‐USG during the course of radiotherapy due to head and neck cancers, and (b) to determine whether there is any connection between skin sonograms and the skin scoring criteria. This prospective, observational study includes patients diagnosed with head and neck cancers, treated with radiotherapy or concomitant chemoradiation. The final analysis includes six patients. In every patient, the HF‐USG as well as dermatological assessment (target lesion score—TLS and CACE v. 4.0) were performed 4×: before, in the middle, day after, and 3 months after radiotherapy. There were significant differences between non‐irradiated skin thickness and thickness of skin with clinically obvious radiodermatitis (TLS grade 1‐4; P < .0001), as well as between irradiated, unchanged skin thickness (TLS grade 0) and thickness of skin with clinically obvious radiodermatitis (TLS grade 1‐4; P = .0002). There was no significant difference between non‐irradiated and irradiated, unchanged skin thickness (TLS grade 0; P = .9318). In four patients, we demonstrated subepidermal low echogenic band (SLEB). HF‐USG can be useful tool to noninvasive and objective assessment of skin changes during radiotherapy. 相似文献
27.
Jean‐Franois Etter 《Addiction (Abingdon, England)》2019,114(12):2252-2256
28.
29.