全文获取类型
收费全文 | 38026篇 |
免费 | 2805篇 |
国内免费 | 81篇 |
专业分类
耳鼻咽喉 | 275篇 |
儿科学 | 902篇 |
妇产科学 | 773篇 |
基础医学 | 5136篇 |
口腔科学 | 896篇 |
临床医学 | 4585篇 |
内科学 | 6685篇 |
皮肤病学 | 593篇 |
神经病学 | 3491篇 |
特种医学 | 1488篇 |
外科学 | 5095篇 |
综合类 | 677篇 |
一般理论 | 45篇 |
预防医学 | 4622篇 |
眼科学 | 653篇 |
药学 | 2701篇 |
1篇 | |
中国医学 | 51篇 |
肿瘤学 | 2243篇 |
出版年
2023年 | 209篇 |
2022年 | 374篇 |
2021年 | 738篇 |
2020年 | 497篇 |
2019年 | 727篇 |
2018年 | 853篇 |
2017年 | 645篇 |
2016年 | 673篇 |
2015年 | 855篇 |
2014年 | 1130篇 |
2013年 | 1566篇 |
2012年 | 2449篇 |
2011年 | 2485篇 |
2010年 | 1443篇 |
2009年 | 1333篇 |
2008年 | 2153篇 |
2007年 | 2319篇 |
2006年 | 2122篇 |
2005年 | 2129篇 |
2004年 | 2092篇 |
2003年 | 1989篇 |
2002年 | 1782篇 |
2001年 | 748篇 |
2000年 | 767篇 |
1999年 | 717篇 |
1998年 | 446篇 |
1997年 | 337篇 |
1996年 | 353篇 |
1995年 | 276篇 |
1994年 | 254篇 |
1993年 | 233篇 |
1992年 | 482篇 |
1991年 | 445篇 |
1990年 | 432篇 |
1989年 | 400篇 |
1988年 | 337篇 |
1987年 | 362篇 |
1986年 | 317篇 |
1985年 | 324篇 |
1984年 | 304篇 |
1983年 | 258篇 |
1982年 | 153篇 |
1980年 | 149篇 |
1979年 | 203篇 |
1978年 | 157篇 |
1976年 | 139篇 |
1975年 | 143篇 |
1974年 | 144篇 |
1973年 | 148篇 |
1972年 | 150篇 |
排序方式: 共有10000条查询结果,搜索用时 9 毫秒
41.
Arnold Criel Gregor Verhoef Robert Vlietinck Cristina Mecucci Johan Billiet Lucienne Michaux Peter Meeus ries Louwagie Angeline Van Orshoven Achiel Van Hoof Mark Boogaerts Herman Van den Berghe & Chris De Wolf-Peeters 《British journal of haematology》1997,97(2):383-391
We analysed a group of 390 patients, diagnosed with chronic lymphocytic leukaemia (CLL). Cases were subclassified as morphologically typical and atypical CLL according to the criteria of the FAB proposal. Typical CLL cases were mostly diagnosed at a low-risk stage (Binet A/Rai 0), required no immediate treatment and expected a long survival; atypical CLL cases mostly presented at a more advanced risk stage (Binet B/Rai I–II), usually required immediate treatment and their survival was shorter. Moreover, clinical staging was of prognostic significance in typical but not in atypical cases. In typical CLL, del(11q) was the most common chromosomal abnormality (21%) whereas in atypical CLL trisomy 12 was found in about 65% of the cases documented with an abnormal karyotype. Although chromosomal abnormalities were associated with a poor survival in typical CLL, they are of no prognostic significance in atypical CLL. Based on these data, we conclude that subtyping CLL by morphology enables the identification of two groups of cases, each characterized by a specific clinical presentation, different cytogenetic abnormalities and prognostic parameters. We speculate that these two groups may represent two related, but different, diseases with different prognostic parameters and a different survival. 相似文献
42.
43.
44.
45.
M C Nahata D R King D A Powell S M Marx M E Ginn-Pease 《JPEN. Journal of parenteral and enteral nutrition》1988,12(1):58-59
Broviac catheters are commonly used to provide parenteral nutrition and access for infusion of blood products and drugs to pediatric patients. Sepsis is the most common serious complication of continued catheter use. Although removal of the catheter is generally recommended when it becomes contaminated, it may not be feasible to do so without compromising patient care. We evaluated the management of catheter-related infections in pediatric patients with and without removal of catheter. Seventy-seven episodes of catheter sepsis were evaluated in 61 pediatric patients; 24 were neonates and 37 were older children. The catheters were used for multiple purposes in 75% of cases. The most common microorganisms isolated were Staphylococcus epidermidis in 26%, Klebsiella pneumoniae in 9%, and Streptococcus viridans in 8% of cases; other pathogens included group D Enterococcus, Staphylococcus aureus, and Escherichia coli. Pseudomonas aeruginosa was isolated in four older children. Thirty-five patients were treated with antibiotics without catheter removal. Thirty patients received appropriate antibiotic therapy based on the susceptibility data. Twenty-six of these 30 patients responded within 5 days of therapy whereas the others required 15-39 days of treatment. Lack of response was mainly associated with the presence of abscess, immunocompromised status, and organisms P. aeruginosa and Candida albicans. Based on the sensitivity and minimum inhibitory concentration data, a combined regimen of gentamicin and vancomycin would be an effective initial therapy. These findings suggest that (1) catheter sepsis can be managed with appropriate antibiotics, and (2) when continued use of Broviac catheter is desired, a trial of antibiotic therapy should be attempted before catheter removal. 相似文献
46.
Eileen J. Martin Kiran S. Panickar Michael A. King Malgorzata Deyrup Bruce E. Hunter Geehuan Wang Edwin M. Meyer 《Drug development research》1994,31(2):135-141
The potential cytoprotective actions of a novel nicotinic agent 2,4-dimethoxybenzilidene anabaseine (DMXB) were investigated in differentiated PC12 cells and transected rat septal cholinergic neurons in vivo. In NGF-differentiated PC12 cells, removal of both NGF and serum led to cell loss, a reduced % of cells expressing neurites, the release of lactate dehydrogenase, and a decrease in total cellular protein. Cell loss was apparent within 24 h, and remained constant between 4–8 days post-NGF removal. NGF alone (100 ng/ml), DMXB (10 μM), but not nicotine (10 μM), prevented these cell and neurite losses. DMXB-induced cytoprotection was blocked by 1 μM mecamylamine. DMXB (1 mg/kg, ip) injected twice but not once per day protected cholinesterase-staining septal neurons from retrograde degeneration following unilateral fimbrial transections. The twice per day DMXB injection-protocol also decreased cell roundness among cholinesterase-staining cells in the lesioned septal hemisphere compared to saline-injected animals. These studies suggest that DMXB may exert cytoprotective activity in NGF-sensitive neuronal populations. © 1994 Wiley-Liss, Inc. 相似文献
47.
High-level language functioning was assessed in a group of 11 children with severe closed head injury (CHI). Performance was examined on measures of figurative language, oral expression, inferencing, and interpretation of ambiguous sentences, and was compared with that of a control group matched for age, gender, and handedness. The children with CHI demonstrated inferior performance on the oral expression, ambiguous sentences, and figurative language tests; however, performance on the inferencing task appeared intact. These findings are discussed with respect to the underlying nature of the observed impairments. Both linguistic and cognitive factors are considered. It is concluded that a complex interaction of cognitive and linguistic impairments experienced by children with CHI may underlie the performance deficits identified in the current study. 相似文献
48.
Lamiya Samad Chris Hollis Martin Prince Robert Goodman 《International journal of methods in psychiatric research》2005,14(4):230-230
The original article to which this Erratum refers was published in International Journal of Methods in Psychiatric Research, 2005; Vol.14, No.3, 158–166. Copyright © 2005 John Wiley & Sons, Ltd. 相似文献
49.
50.