全文获取类型
收费全文 | 308627篇 |
免费 | 59974篇 |
国内免费 | 6203篇 |
专业分类
耳鼻咽喉 | 4189篇 |
儿科学 | 8651篇 |
妇产科学 | 5140篇 |
基础医学 | 44992篇 |
口腔科学 | 9281篇 |
临床医学 | 38397篇 |
内科学 | 59896篇 |
皮肤病学 | 12125篇 |
神经病学 | 26965篇 |
特种医学 | 12601篇 |
外国民族医学 | 16篇 |
外科学 | 39457篇 |
综合类 | 21396篇 |
现状与发展 | 28篇 |
一般理论 | 105篇 |
预防医学 | 21896篇 |
眼科学 | 7438篇 |
药学 | 28724篇 |
156篇 | |
中国医学 | 9654篇 |
肿瘤学 | 23697篇 |
出版年
2024年 | 399篇 |
2023年 | 1997篇 |
2022年 | 5149篇 |
2021年 | 10052篇 |
2020年 | 10399篇 |
2019年 | 15808篇 |
2018年 | 16082篇 |
2017年 | 16436篇 |
2016年 | 17583篇 |
2015年 | 20244篇 |
2014年 | 22455篇 |
2013年 | 24869篇 |
2012年 | 23775篇 |
2011年 | 23771篇 |
2010年 | 21437篇 |
2009年 | 16048篇 |
2008年 | 16801篇 |
2007年 | 15383篇 |
2006年 | 14087篇 |
2005年 | 12600篇 |
2004年 | 10519篇 |
2003年 | 9289篇 |
2002年 | 8022篇 |
2001年 | 6630篇 |
2000年 | 5877篇 |
1999年 | 4314篇 |
1998年 | 1731篇 |
1997年 | 1404篇 |
1996年 | 1297篇 |
1995年 | 1144篇 |
1994年 | 1039篇 |
1993年 | 808篇 |
1992年 | 1687篇 |
1991年 | 1679篇 |
1990年 | 1451篇 |
1989年 | 1319篇 |
1988年 | 1224篇 |
1987年 | 1082篇 |
1986年 | 1048篇 |
1985年 | 914篇 |
1984年 | 662篇 |
1983年 | 568篇 |
1982年 | 409篇 |
1981年 | 392篇 |
1980年 | 342篇 |
1979年 | 522篇 |
1978年 | 409篇 |
1977年 | 393篇 |
1976年 | 343篇 |
1974年 | 363篇 |
排序方式: 共有10000条查询结果,搜索用时 203 毫秒
31.
目的分析妊娠早期阴道微环境变化及与阴道炎症的关系。方法回顾性分析2017年3月-2018年12月韶关市曲江区妇幼保健计划生育服务中心104例妊娠早期孕产妇临床资料。记录其非妊娠期及妊娠早期阴道微环境变化情况,包括酸碱度(pH)、菌群密集度、菌群多样性、阴道微生物功能正常率、乳杆菌阳性率、阴道微生态正常率,并比较妊娠早期阴道炎症发生情况及其阴道微环境。结果孕产妇非妊娠期pH、阴道微生物功能正常率、乳杆菌阳性率及阴道微生态正常率明显高于妊娠早期,菌群密集度、菌群多样性则低于妊娠早期,差异均有统计学意义(P<0.05)。孕产妇妊娠早期阴道炎症组pH、菌群密集度、菌群多样性明显高于无阴道炎症组,阴道微生物功能正常率及乳杆菌阳性率则低于无阴道炎症组,差异均有统计学意义(P<0.05)。结论妊娠早期阴道微环境出现一系列变化,造成阴道炎症发生率升高,对此临床应给予重视。 相似文献
32.
目的研究新生儿肺炎(NP)患儿血清高敏C反应蛋白(hs-CRP)、降钙素原(PCT)、白细胞介素-6(IL-6)水平表达及其意义。方法选取2017年1月-2018年2月韶关市曲江区妇幼保健计划生育服务中心诊治的NP患儿80例,按细菌感染情况分为观察1组和观察2组,各40例。选择同期40例健康新生儿作为对照组。测定并比较三组的hs-CRP、PCT和IL-6水平。结果观察1组血清PCT、hs-CRP和IL-6水平明显高于观察2组和对照组,差异均有统计学意义(P<0.05)。观察1组血清PCT、hs-CRP和1L-6检测阳性率明显高于观察2组和对照组,差异均有统计学意义(P<0.05),且观察1组血清PCT、hs-CRP和1L-6诊断NP的敏感度均明显高于观察2组,差异均有统计学意义(P<0.05);观察组各指标特异度与观察2组比较差异无统计学意义(P>0.05)。结论血清hs-CRP、PCT、IL-6水平可作为NP患儿的辅助鉴别指标,为抗生素的合理使用和疗效提供依据。 相似文献
33.
34.
Ángel Becerra Héctor Trujillo Lucía Valencia Aurelio Rodríguez‐Pérez 《Brazilian Journal of Anesthesiology》2019,69(2):200-203
Background and objectives
A prompt and effective management of trauma patient is necessary. The aim of this case report is to highlight the importance of intraoperative echocardiography as a useful tool in patients suffering from refractory hemodynamic instability no otherwise explained.Case report
A 41 year‐old woman suffered a car accident. At the emergency department, no abnormalities were found in ECG or chest X‐ray. Abdominal ultrasound revealed the presence of abdominal free liquid and the patient was submitted to urgent exploratory laparotomy. Nevertheless, she persisted suffering arterial hypotension and metabolic acidosis. Looking for the reason of her hemodynamic instability, intraoperative transthoracic echocardiography was performed, finding out the presence of pericardial effusion. Once the cardiac surgeon extracted pericardial clots, patient's situation improved clinically and analytically.Conclusion
Every anesthesiologist should be able to use the intraoperative echocardiography as an effective tool in order to establish the appropriate measures to promote the survival of patients suffering severe trauma. 相似文献35.
36.
37.
38.
Hyun Jong Choi Jong Ho Moon Yun Nah Lee Hyun Su Kim Ji Su Ha Tae Hoon Lee Sang‐Woo Cha Young Deok Cho Sang‐Heum Park 《Digestive endoscopy》2015,27(7):772-775
Direct peroral cholangioscopy (POC) using an ultra‐slim upper endoscope is one modality of POC for intraductal endoscopic evaluation and treatment of the bile duct. Choledochoduodenostomy (CDS) is one modality of biliary bypass surgery that provides a new route to the bile duct. We carried out direct POC using an ultra‐slim upper endoscope without the use of accessories in 10 patients (four sump syndromes, three bile duct strictures and three intrahepatic duct stones) previously undergoing surgical CDS. Direct POC was successful in all patients. The use of an intraductal balloon catheter was required in one patient for advancement of the endoscope into the bile duct. Distal bile ducts with sump syndromes were cleared using baskets and water irrigation under direct POC. Cholangiocarcinoma was diagnosed in one patient with hilar bile duct stricture after cholangioscopic evaluation and a targeting forceps biopsy under direct POC. Intrahepatic duct stones were successfully extracted after intraductal fragmentation under direct POC. Oozing bleeding occurred during intraductal lithotripsy but stopped spontaneously. Direct POC using an ultra‐slim upper endoscope without the assistance of accessories can easily be carried out in patients undergoing CDS. 相似文献
39.
Autoimmune comorbid diseases associated with lichen planus: a nationwide case–control study 下载免费PDF全文
40.
M.T. Leccia N. Auffret F. Poli J.‐P. Claudel S. Corvec B. Dreno 《Journal of the European Academy of Dermatology and Venereology》2015,29(8):1485-1492
Acne vulgaris (acne) is a chronic inflammatory disease of the sebaceous gland, characterized by follicular hyperkeratinization, excessive colonization by Propionibacterium acnes (P. acnes) as well as immune reactions and inflammation. Despite an armamentarium of topical treatments available including benzoyl peroxide, retinoids and azelaic acid, topical antibiotics in monotherapies, especially erythromycin and clindamycin, are still used in Europe to treat acne. This intensive use led to antimicrobial‐resistant P. acnes and staphylococci strains becoming one of the main health issues worldwide. This is an update on the current topical acne treatments available in Europe, their mechanism of action, their potential to induce antimicrobial resistance and their clinical efficacy and safety. 相似文献