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51.
Sebastian D. Sahli Alexander Kaserer Julia Braun Maximilian Halbe Yuliya Dahlem Muriel A. Spahn Julian Rssler Bernard Krüger Francesco Maisano Donat R. Spahn Markus J. Wilhelm 《Journal of thoracic disease》2022,14(6):1960
BackgroundExtracorporeal life support (ECLS) therapy is increasingly used for cardiac and respiratory support postcardiotomy, refractory cardiogenic shock and cardiopulmonary resuscitation. This study aims to describe in-hospital mortality of patients requiring ECLS, identify independent predictors associated with mortality and analyze changes of mortality over time.MethodsThis retrospective study includes all adult ECLS cases at the University Hospital Zurich, a designated ECLS center in Switzerland, in the period 2007 to 2019.ResultsECLS therapy was required in 679 patients (median age 60 years, 27.5% female). In-hospital mortality was 55.5%. Cubic spline interpolation did not detect evidence for a change in mortality over the whole period of 13 years. In-hospital mortality significantly varied between ECLS indications: 70.7% (152/215) for postcardiotomy, 67.9% (108/159) for cardiopulmonary resuscitation, 47.0% (110/234) for refractory cardiogenic shock, and 9.9% (7/71) for lung transplantation and expansive thoracic surgery (P<0.001). Logistic regression modelling showed excellent discrimination in the receiver operating characteristic (ROC) area under the curve (AUC) of 0.89 [95% confidence interval (CI): 0.87–0.92] and identified significant mortality predictors: age, simplified acute physiology score (SAPS) II, as well as new liver failure and each allogenic blood transfusion unit given per day. ECLS after cardiopulmonary resuscitation was associated with significantly higher mortality compared to ECLS for refractory cardiogenic shock.ConclusionsIn-hospital mortality of patients treated with ECLS therapy is high. Outcomes have not changed significantly in the observed period. We identified age, SAPS II, new liver failure and each allogenic blood transfusion unit given per day as independent mortality predictors. Knowledge of predictors strongly associated with in-hospital mortality may affect future decisions about ECLS indications and the respective management to use this elaborate therapy more effectively. 相似文献
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Reinaldo Dal Bello Justine Pasanisi Romane Joudinaud Matthieu Duchmann Bryann Pardieu Paolo Ayaka Giuseppe Di Feo Gaetano Sodaro Clmentine Chauvel Rathana Kim Loic Vasseur Laureen Chat Frank Ling Kim Pacchiardi Camille Vaganay Jeannig Berrou Chaima Benaksas Nicolas Boissel Thorsten Braun Claude Preudhomme Herv Dombret Emmanuel Raffoux Nina Fenouille Emmanuelle Clappier Lionel Ads Alexandre Puissant Raphael Itzykson 《Blood cancer journal》2022,12(6)
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Hind Sahli Jihad Boularab Jihane El Mandour Nazik Allali Latifa Chat Siham El Haddad 《Radiology Case Reports》2022,17(7):2315
Extramedullary hematopoiesis is a rare disorder in which hematopoietic cells proliferate in tissues other than the bone marrow as a result of a range of hematologic illnesses. Our case is unique in that it covers a number of extramedullary hematopoiesis sites in a 15-year-old girl, some of which are uncommon. 相似文献
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Kouki Chaima Amouri Mariem Bahloul Emna Charfi Slim Hammemi Fatma Boudawara Tahya Turki Hamida 《Clinical Case Reports》2022,10(6)
Panniculitis has various etiologies. One of the less common causes is trauma and hence traumatic fat necrosis (FN). These soft tissue injuries usually appear on the shins, thighs, breasts, arms, and buttocks. FN is mainly caused by trauma and may be associated with other conditions such as pancreatic disease. FN arising after intramuscular injections is uncommon and usually appears as firm, encapsulated, mobile, nontender, and solitary or multiple subcutaneous nodules. We report an interesting case of FN caused by intramuscular injections of cefazolin and meglumine antimoniate (MA) in a 38‐year‐old female patient. MA is regarded as the first‐line systemic treatment for cutaneous leishmaniasis (CL). However, these drugs are not devoid of various potentially adverse reactions. 相似文献
55.
Anis Grassa Meriem Yazidi Jihene Marrakchi Chaima Bel Hadj Sliman Ibtissem Oueslati Melika Chihaoui 《Clinical Case Reports》2022,10(8)
Pallister–Hall syndrome (PHS) is a very rare genetic disorder. The diagnosis is usually suspected at the young age when a hypothalamic hamartoma is associated with polydactyly. Endocrine manifestations are mostly related to hypothalamic hamartoma and rarely reveal the disease. We report the case of an 18‐year‐old young man in whom the diagnosis of PHS was delayed until his hospitalization in the endocrinology department for acute adrenal insufficiency. 相似文献
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An ecological approach to discover new bioactive extracts and products: the case of extremophile plants 下载免费PDF全文
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Zeyad T Sahli Farah Karipineni Jen-Fan Hang Joseph K Canner Aarti Mathur Jason D Prescott Sheila Sheth Syed Z Ali Martha A Zeiger 《Surgery》2019,165(1):69-74