全文获取类型
收费全文 | 3341篇 |
免费 | 373篇 |
国内免费 | 126篇 |
专业分类
耳鼻咽喉 | 15篇 |
儿科学 | 74篇 |
妇产科学 | 53篇 |
基础医学 | 465篇 |
口腔科学 | 45篇 |
临床医学 | 336篇 |
内科学 | 541篇 |
皮肤病学 | 27篇 |
神经病学 | 248篇 |
特种医学 | 65篇 |
外科学 | 369篇 |
综合类 | 261篇 |
一般理论 | 2篇 |
预防医学 | 439篇 |
眼科学 | 86篇 |
药学 | 287篇 |
中国医学 | 89篇 |
肿瘤学 | 438篇 |
出版年
2023年 | 39篇 |
2022年 | 78篇 |
2021年 | 136篇 |
2020年 | 73篇 |
2019年 | 75篇 |
2018年 | 97篇 |
2017年 | 66篇 |
2016年 | 74篇 |
2015年 | 79篇 |
2014年 | 97篇 |
2013年 | 108篇 |
2012年 | 200篇 |
2011年 | 369篇 |
2010年 | 224篇 |
2009年 | 208篇 |
2008年 | 176篇 |
2007年 | 162篇 |
2006年 | 150篇 |
2005年 | 168篇 |
2004年 | 295篇 |
2003年 | 190篇 |
2002年 | 120篇 |
2001年 | 75篇 |
2000年 | 68篇 |
1999年 | 43篇 |
1998年 | 31篇 |
1997年 | 28篇 |
1996年 | 21篇 |
1995年 | 9篇 |
1994年 | 12篇 |
1993年 | 11篇 |
1992年 | 37篇 |
1991年 | 19篇 |
1990年 | 19篇 |
1989年 | 16篇 |
1988年 | 15篇 |
1987年 | 26篇 |
1986年 | 23篇 |
1985年 | 18篇 |
1984年 | 9篇 |
1983年 | 12篇 |
1982年 | 8篇 |
1981年 | 8篇 |
1979年 | 8篇 |
1977年 | 10篇 |
1975年 | 8篇 |
1974年 | 9篇 |
1972年 | 10篇 |
1968年 | 9篇 |
1966年 | 7篇 |
排序方式: 共有3840条查询结果,搜索用时 781 毫秒
81.
Cassandra R. OLenick Amir Baniassadi Ryan Michael Andrew Monaghan Jennifer Boehnert Xiao Yu Mary H. Hayden Christine Wiedinmyer Kai Zhang Peter J. Crank Jannik Heusinger Paige Hoel David J. Sailor Olga V. Wilhelmi 《Environmental health perspectives》2020,128(12)
Background: Despite the substantial role indoor exposure has played in heat wave–related mortality, few epidemiological studies have examined the health effects of exposure to indoor heat. As a result, knowledge gaps regarding indoor heat–health thresholds, vulnerability, and adaptive capacity persist.Objective: We evaluated the role of indoor heat exposure on mortality and morbidity among the elderly ( of age) in Houston, Texas.Methods: Mortality and emergency hospital admission data were obtained through the Texas Department of State Health Services. Summer indoor heat exposure was modeled at the U.S. Census block group (CBG) level using building energy models, outdoor weather data, and building characteristic data. Indoor heat–health associations were examined using time-stratified case-crossover models, controlling for temporal trends and meteorology, and matching on CBG of residence, year, month, and weekday of the adverse health event. Separate models were fitted for three indoor exposure metrics, for individual lag days 0–6, and for 3-d moving averages (lag 0–2). Effect measure modification was explored via stratification on individual- and area-level vulnerability factors.Results: We estimated positive associations between short-term changes in indoor heat exposure and cause-specific mortality and morbidity [e.g., circulatory deaths, (95% CI: 1.03, 1.30)]. Associations were generally positive for earlier lag periods and weaker across later lag periods. Stratified analyses suggest stronger associations between indoor heat and emergency hospital admissions among African Americans compared with Whites.Discussion: Findings suggest excess mortality among certain elderly populations in Houston who are likely exposed to high indoor heat. We developed a novel methodology to estimate indoor heat exposure that can be adapted to other U.S. locations. In locations with high air conditioning prevalence, simplified modeling approaches may adequately account for indoor heat exposure in vulnerable neighborhoods. Accounting for indoor heat exposure may improve the estimation of the total impact of heat on health. https://doi.org/10.1289/EHP6340 相似文献
82.
83.
84.
85.
Abraham Khan Aram Kim Cassandra Sanossian Fritz Francois 《World journal of gastroenterology : WJG》2016,(4):1627-1638
Gastroesophageal reflux disease(GERD) is a frequently encountered disorder. Obesity is an important risk factor for GERD, and there are several pathophysiologic mechanisms linking the two conditions. For obese patients with GERD, much of the treatment effort is focused on weight loss and its consistent benefit to symptoms, while there is a relative lack of evidence regarding outcomes after novel or even standard medical therapy is offered to this population. Physicians are hesitant to recommend operative anti-reflux therapy to obese patients due to the potentially higher risks and decreased efficacy, and these patients instead are often considered for bariatric surgery. Bariatric surgical approaches are broadening, and each technique has emerging evidence regarding its effect on both the risk and outcome of GERD. Furthermore, combined antireflux and bariatric options are now being offered to obese patients with GERD. However, currently Rouxen-Y gastric bypass remains the most effective surgical treatment option in this population, due to its consistent benefits in both weight loss and GERD itself. This article aims to review the impact of both conservative and aggressive approaches of obesity treatment on GERD. 相似文献
86.
George Fein Kameron Key Michael D. Szymanski 《Alcoholism, clinical and experimental research》2010,34(7):1127-1139
Background: There is considerable evidence that alcoholics differ from nonalcoholics in the processing of stimuli that have emotional content. The current study examines those differences that are present in multi‐year abstinent individuals. Methods: We compared reaction time (RT), accuracy, and Event Related Potentials (ERP) measures in long‐term abstinent alcoholics (LTAA, n = 52) with that in age‐ and gender‐comparable nonalcoholic controls (NAC, n = 47). Subjects were presented with male and female faces exhibiting happy, neutral, or sad facial expressions and were instructed to identify the picture gender in 1 task and the emotion being expressed in a subsequent task. Results: LTAA had slower RTs than NAC when instructed to identify emotion, while RT was comparable when identifying gender. There were no differences between groups on task accuracy. P160 latency was increased in LTAA for both tasks compared to NAC, though P160 amplitude did not differ between groups. The P160 effect was about 5 × as large as the RT effect and was statistically independent of the RT effect, while the RT effect was no longer present after removing variance because of the P160 effect. Conclusions: Our data demonstrate slower early processing of emotional facial stimuli in alcoholics that is unresolved by long‐term abstinence and is most sensitively indexed by delayed P160 latency in LTAA. 相似文献
87.
Key NS 《British journal of haematology》2004,127(4):379-391
The development of inhibitory 'allo' antibodies to a deficient coagulation factor is arguably now the most severe and important complication of clotting factor concentrate exposure in haemophilia and other congenital coagulation disorders. Furthermore, development of an inhibitor to the factor VIII or factor IX transgene product remains a significant concern in gene therapy protocols for haemophilia. Although the development of an inhibitor does not usually change the rate, initial severity or pattern of bleeding, it does compromise the ability to manage haemorrhage in affected individuals, resulting in a greater rate of complications, cost and disability. The purpose of this review is to summarize current understanding of the epidemiology, immunobiology, laboratory evaluation and management of inhibitors arising in patients with congenital coagulation disorders. An attempt has been made to focus on recent advances in the immunology of inhibitors, and to speculate on their potential clinical application. 相似文献
88.
89.
90.