A Fetal Hemoglobin Variant of Unusual Genetic Interest

A fetal hemoglobin variant abnormal in the peptide chains has beenfound in an umbilical cord blood sample obtained from an infant who hadinherited Hb-G (presumably identical with G_Phila.) from his father. This provides evidence that chain synthesis in fetal and adult life is under a singlegenetic control and that chain mutations, unlike chain mutations, may bemanifested in intrauterine life.

     

Blunt Trauma and Liver Abscess

Three cases of pyogenic liver abscess following blunt trauma to the torso are described. The association between blunt trauma with liver contusion and the development of bacterial pyogenic liver abscess is explored. Reported series of liver abscess are reviewed. It is suggested that physicians look for the development of liver abscess in patients who have had major blunt trauma to the torso. Physicians should also inquire about blunt trauma in patients with documented pyogenic liver abscesses.