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SISTO PERDONÀ RICCARDO AUTORINO LUIGI GALLO MARCO DE SIO LUIGI MARRA LUIGI CLAUDIO CORRADO CARACÒ RENATO FRANCO FLAVIO FAZZIOLI ANTONIO GALLO 《International journal of urology》2005,12(4):401-404
Solitary metastases to the small bones and/or to the soft tissue of the hands and feet (acrometastases) are rare. We report a case of renal cell carcinoma (RCC) with big toe metastasis revealed before the primary tumor became apparent. The best treatment for a single metastasis is always surgical excision, regardless of the lesion being synchronous or metachronous. The biological behavior of metastatic RCC is unpredictable and only early diagnosis and treatment may favorably affect patient survival. Thus, metastatic RCC should be included in the differential diagnosis of all enlarging cutaneous nodules, wherever they develop. 相似文献
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Association between Beta1‐Adrenergic Receptor Polymorphism and Risk of ICD Shock in Heart Failure Patients
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Miniaturized Implantable Loop Recorder in Small Patients: An Effective Approach to the Evaluation of Subjects at Risk of Sudden Death
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SILVIA PLACIDI M.D. FABRIZIO DRAGO M.D. MADDALENA MILIONI M.D. LETIZIA VERTICELLI C.C.P. ILARIA TAMBURRI C.C.P. MASSIMO STEFANO SILVETTI M.D. CORRADO DI MAMBRO M.D. DANIELA RIGHI M.D. FABRIZIO GIMIGLIANO M.D. MARIO SALVATORE RUSSO M.D. Ph.D. ROSALINDA PALMIERI M.D. ROMOLO REMOLI M.D. LORENZO MARIA SANTUCCI M.D. Ph.D. ALBERTO EUGENIO TOZZI M.D. 《Pacing and clinical electrophysiology : PACE》2016,39(7):669-674
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GIUSEPPE COPPOLA M.D. Ph .D. DANIELA GUTTILLA M.D. EGLE CORRADO M.D. CALOGERO FALLETTA M.D. † GIANLUCA MARRONE M.D. ‡ RICCARDO AIRÒ FARULLA M.D. GIANFRANCO CIARAMITARO M.D. Ph .D. PASQUALE ASSENNATO M.D. SALVATORE NOVO M.D. F.P. 《Pacing and clinical electrophysiology : PACE》2009,32(8):1092-1095
Isolated noncompaction of the ventricular myocardium (INVM) is an uncommon cardiomyopathy characterized by the persistence of fetal myocardium with prominent trabecular meshwork and deep intertrabecular recesses, often associated with systolic dysfunction and ventricular dilatation. A 23-year-old man from Burkina Faso was referred to our operative unit with a diagnosis of INVM, made with echocardiogram and magnetic resonance imaging and nonsustained ventricular tachycardia. The literature reports the incidence of malignant ventricular arrhythmias in as many as 47% of the patients and sudden cardiac death in almost 50% of them and this supported our decision to perform implantable cardioverter-defibrillators implantation. 相似文献
66.
VALENTIN LOZANOV CORRADO GUARNACCIA ANDRS PATTHY SALVATORE FOT SNDOR PONGOR 《Chemical biology & drug design》1997,50(1):65-72
We report here the total synthesis of the α-amylase inhibitor (AAI), a 32-residue-long peptide with three disulfide bridges, isolated from amaranth seeds (Chagolla-Lopez, A., Blanco-Labra, A., Patthy, A., Sanchez, R. & Pongor S. (1994) J. Biol. Chem. 269 , 23675–23680). The synthesis was carried out using a stepwise solid-phase approach based on the Fmoc/t-Bu chemistry, combined with the S-acetamidomethyl protection for cysteines. The linear, reduced peptide was obtained after two reduction steps, using 1, 4-dithio-dl -threitol and tri(2-carboxyethyl)phosphine hydrochloride in basic and acidic conditions, respectively. Disulfide bridges were formed by oxidative folding in a cystine/cysteine redox buffer, these conditions were found superior to air oxidation and to glutathione-catalyzed oxidative folding. The physicochemical and enzyme inhibitory properties of synthetic AAI were found identical with those of the natural product. Several orthogonal protection schemes proved unsuccessful in obtaining a biologically active product. 相似文献
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ANDREA GIUSTINA CORRADO BODINI SIMONETTA BOSSONI MAURO DOGA ANGELA GIRELLI GIUSEPPE PIZZOCOLO WILLIAM B. WEHRENBERG 《Clinical endocrinology》1990,33(3):375-380
Studies in man demonstrated that salmon calcitonin (sCT) administration blunts the pituitary GH response to GH-releasing hormone (GHRH). However, the mechanisms underlying this inhibitory action of CT in man are unclear. Pyridostigmine (PD), an acetylcholinesterase inhibitor, is hypothesized to enhance the GH response to GHRH in normal subjects probably via a decrease in the somatostatinergic tone. The aim of the present study was to investigate the mechanism of the inhibitory action of sCT on the GH response to human GHRH (1-29) NH2 by concomitant PD administration in normal humans. The GH response to GHRH was significantly suppressed by prior administration of sCT. Pretreatment of subjects with PD significantly enhanced the GH response to GHRH but did not alter the inhibitory actions of sCT. We conclude that sCT is able to inhibit GHRH-stimulated GH secretion in man without influencing the hypothalamic somatostatinergic tone. 相似文献
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