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121.
Hiroya Minami Nobuhiko Mukohara Hidefumi Obo Masato Yoshida Ayako Maruo Kim Hyun IL Junichiro Kitahara Takeshi Inoue Akiko Tanaka Tsutomu Shida 《The Japanese Journal of Thoracic and Cardiovascular Surgery》2005,53(3):133-137
Objectives: Coronary artery disease (CAD) and abdominal aortic aneurysms (AAA) commonly coexist. However, each disease treatment complicates
the management of the other. In this study, we evaluate whether a simultaneous operation of AAA repair and off pump coronary
artery bypass (OPCAB) would be safe and acceptable, compared with either procedure alone. Subjects and Methods: We retrospectively reviewed all patients who underwent simultaneous AAA repair and OPCAB (AAA/OPCAB, n=18), compared AAA
repair alone (AAA, n=239) and OPCAB alone (OPCAB, n=137) from June 1999 to December 2003. There were no significant differences
with regard to age or gender, but the AAA/OPCAB group had significantly larger aneurysms (60.6 vs. 53.2 mm) and significantly
lower ejection fractions (EF) (54.9 vs. 60.3%). Results: The patients in the AAA/OPCAB group underwent a significantly longer operative time than AAA, OPCAB (403 vs. 360,296 minutes,
respectively), there was significantly greater blood loss (726 vs. 426, 462 ml), and more transfusion required (8.13 vs. 1.69,
2.8 units). The number of bypass grafts in AAA/OPCAB group (1–5 per patients) was significantly smaller (1.78 vs. 2.93). The
AAA/OPCAB patients had a significantly longer hospital stay than the AAA (38 vs. 22 days), but was not significantly longer
than the OPCAB. There were no significant differences with regard to the morbidity and mortality rate among the three groups.
Conclusion: This study suggests that the simultaneous operation of AAA and OPCAB can be done with the same morbidity and mortality as
independent surgical procedures. Key words: coronary artery bypass grafting, abdominal aortic aneurysm, off pump coronary
artery bypass, simultaneous operation 相似文献
122.
S100A7 (psoriasin) inhibits human epidermal differentiation by enhanced IL‐6 secretion through IκB/NF‐κB signalling 下载免费PDF全文
Eui Dong Son Hyoung‐June Kim Kyu Han Kim Bum Ho Bin IL‐Hong Bae Kyung‐Min Lim Seok Jong Yu Eun‐Gyung Cho Tae Ryong Lee 《Experimental dermatology》2016,25(8):636-641
Psoriasin (S100A7), a member of the S100 protein family, is a well‐known antimicrobial peptide and a signalling molecule which regulates cellular function and is highly expressed in hyperproliferative skin conditions such as atopic dermatitis (AD) and psoriasis with disrupted skin barrier function. However, its role in epidermal differentiation remains unknown. We examined the effect of S100A7 on epidermal differentiation in normal human keratinocytes (NHKs) and on a reconstituted human epidermis model. When NHKs were exposed to disruptive stimuli such as Staphylococcus aureus, ultraviolet irradiation and retinoic acid, the secretion of S100A7 into the culture medium increased and the expression of epidermal differentiation markers decreased. Treatment of NHKs with S100A7 significantly inhibited epidermal differentiation by reducing the expression of keratin 1, keratin 10, involucrin and loricrin and by increasing the expression of abnormal differentiation markers (keratin 6 and keratin 16). We verified that the MyD88‐IκB/NF‐κB signal cascade was activated via RAGE after S100A7 treatment, resulting in the upregulation of interleukin‐6. Finally, we confirmed that S100A7 is a negative regulator of epidermal differentiation using a reconstituted human epidermis model. This study suggests that S100A7‐related signalling molecules could be potent targets for recovering skin barrier function in AD and psoriasis where S100A7 is accumulated excessively. 相似文献
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125.
Min-Jung Choi PhD RN Hyun-Ju Seo PhD MPH RN IL Han Choo PhD MD Jeong Lan Kim PhD MD Jeong-Min Park PhD RN 《Nursing & health sciences》2023,25(3):402-410
This study aimed to examine the association of COVID-19-related stress, anxiety, access to public healthcare services, and the presence of secondary caregivers (CGs) on the burden of caregiving and health-related quality of life (HRQoL) for CGs of people with dementia (PwD). A cross-sectional survey with 218 family CGs for PwD was completed in various settings between August and September 2021. The CGs had moderate and severe stress (42.7%) and reported having difficulty accessing public healthcare services (51.8%) and receiving help from secondary CGs (42.7%). In the multivariable linear regression, the stress and anxiety levels related to COVID-19 had a positive association with caregiver burden (β = 4.25, p < 0.001, and β = 5.73, p = 0.032, respectively), with no statistically significant association to HRQoL. Unexpectedly, accessing public healthcare services and supporting the secondary CGs were unrelated to the caregiving burden and HRQoL. Therefore, interventions aiming to alleviate family CGs' stress and anxiety levels should be provided to ensure PwD live in their homes in terms of continuity of public health service delivery. 相似文献
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127.
Summary We report a case of acquired cutaneous lymphangiectasia associated with underlying malignancy, and following an arthrotomy. Clinical and histological features were identical with those of acquired lymphangioma. Lymphangiography showed signs of acquired lymphatic obstruction. Both the underlying tumour and the arthrotomy were thought to be contributory factors. 相似文献
128.
FitzGerald M. P. Mulligan M. Parthasarathy S. 《世界核心医学期刊文摘》2006,2(9):17-18
目的:本研究旨在探讨夜尿与阻塞性睡眠呼吸暂停(O SA)之间的关系及持续气道正压通气(CPA P)治疗对夜尿频率的影响。研究设计:这是一项回顾性研究,研究对象在CPAP治疗前、后(相关阶段)有或无OSA证据,根据睡眠诊断χ2检验比较夜尿发生率,logistic回归分析确定夜尿的预测因子,并用 相似文献
129.
Surgical sperm retrieval through percutaneous epididymal aspiration was
used to manage effectively unexpected obstructive azoospermia on the day of
oocyte retrieval.
相似文献
130.
Female pelvic floor: endovaginal MR imaging of normal anatomy 总被引:4,自引:0,他引:4