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81.
M McJannett P Butow M H N Tattersall J F Thompson 《European journal of cancer prevention》2003,12(5):397-405
A question prompt list (QPL) is a structured list of questions designed to encourage patients to acquire information during a medical consultation. It has been shown to be an effective, inexpensive means of helping cancer patients ask questions in certain content areas when consulting an oncologist. The objective of this study was to develop a QPL for cancer patients seeing a surgeon initially, targeting issues identified by patients as important. Focus groups and structured interviews were convened with 22 cancer patients. One focus group was conducted with allied health professionals. Focus groups were audiotaped, transcribed and content analysed to ensure all issues were identified. The results led to the identification of 59 questions covering five themes. We have grouped the questions under the following themes: preliminary negotiation and discussion of diagnosis and its implications; further investigations--why and how; am I seeing the right doctor--who else should I see?; treatment information and options; and support. Participants believed that the QPL would be useful not only during diagnosis and discussions regarding the surgical care but also subsequently. Patients felt that provision and endorsement of a QPL would assist them to achieve their information needs and participation preferences. 相似文献
82.
83.
Keri L. Rodriguez Frank J. Gambino Phyllis Butow Rebecca Hagerty Robert M. Arnold 《Supportive care in cancer》2007,15(2):153-161
Goals of work Although there are guidelines regarding how conversations with patients about prognosis in life-limiting illness should occur,
there are little data about what doctors actually say. This study was designed to qualitatively analyze the language that
oncologists and cancer patients use when talking about death.
Subjects and methods We recruited 29 adults who had incurable forms of cancer, were scheduled for a first-time visit with one of six oncologists
affiliated with a teaching hospital in Australia, and consented to having their visit audiotaped and transcribed. Using content
analytic techniques, we coded various features of language usage.
Main results Of the 29 visits, 23 (79.3%) included prognostic utterances about treatment-related and disease-related outcomes. In 12 (52.2%)
of these 23 visits, explicit language about death (“terminal,” variations of “death”) was used. It was most commonly used
by the oncologist after the physical examination, but it was sometimes used by patients or their kin, usually before the examination
and involving emotional questioning about the patient’s future. In all 23 (100%) visits, implicit language (euphemistic or
indirect talk) was used in discussing death and focused on an anticipated life span (mentioned in 87.0% of visits), estimated
time frame (69.6%), or projected survival (47.8%).
Conclusions Instead of using the word “death,” most participants used some alternative phrase, including implicit language. Although oncologists
are more likely than patients and their kin to use explicit language in discussing death, the oncologists tend to couple it
with implicit language, possibly to mitigate the message effects. 相似文献
84.
Background
Whereas testicular metastases are in themselves a rare entity, testicular secondaries from an appendiceal carcinoma have not yet been described. The case also illustrates the diagnostic dilemma of a tumour presenting as epididymo-orchitis. 相似文献85.
Summary The var1 locus on yeast mitochondria) DNA is defined by a set of alleles that affect the apparent size (Mr 40,000–44,000) of a mitochondria) translation product (var1), a protein of the mitochondria) 38S ribosomal subunit. Using petite deletion and restriction endonuclease site mapping, we have defined the physical location of all var1 alleles to a specific restriction fragment of roughly 2.1 kbp located between the antibiotic resistance loci ery1 and olil. Surprisingly, from base sequence studies of this region by Tzagoloff et al. (1980), it appears that the DNA fragment we have mapped contains little or none of the structural gene for the var1 protein since the fragment is composed primarily of long stretches of dA + dT interspersed with short clusters high in dG + dC. Nevertheless, by a type of complementation test termed zygotic gene rescue (Strausberg and Butow, 1977), we show that with petites retaining that restriction fragment and short flanking sequences, var1 polypeptide characteristic of the strain from which the petite was derived, is expressed in zygotes formed between the petite and a wild-type tester. Thus the ability of the var1 determinant to act in trans suggests that control of expression of different var1 species involves intermolecular interactions, perhaps at the level of RNA splicing. Our results are discussed in terms of several possible models for the organization and control of the var1 structural gene. 相似文献
86.
87.
Bettina Meiser Melanie A. Price Phyllis N. Butow Belinda Rahman Kathy Tucker Benjamin Cheah Adrian Bickerstaffe John Hopper Kelly-Anne Phillips 《Familial cancer》2014,13(2):153-162
This study assessed the sociodemographic, medical and psychological predictors of accuracy of perceived risk in women at increased genetic risk for ovarian cancer. Women participating in a large cohort study who were at increased risk of ovarian and fallopian tube cancer, had no personal history of cancer and had ≥1 ovary in situ at cohort enrolment, were eligible. Women completed self-administered questionnaires and attended an interview at enrolment. Of 2,868 women unaffected with cancer at cohort enrolment, 561 were eligible. 335 women (59.8 %) overestimated their ovarian cancer risk, while 215 women (38.4 %) accurately estimated their risk, and 10 (1.8 %) underestimated it. Women who did not know their mutation status were more likely to overestimate their risk (OR 1.74, 95 % CI 1.10, 2.77, p = 0.018), as were those with higher cancer-specific anxiety (OR 1.05, 95 % CI 1.02, 1.08, p < 0.001) and/or a mother who had been diagnosed with ovarian cancer (OR 1.98, 95 % CI 1.23, 3.18, p = 0.005). Amongst the group of women who did not know their mutation status, 63.3 % overestimated their risk and the mean perceived lifetime risk of developing ovarian cancer was 42.1 %, compared to a mean objective risk of 6.4 %. A large number of women at increased risk for ovarian cancer overestimate their risk. This is of concern especially in women who are at moderately increased risk only; for this sub-group of women, interventions are needed to reduce potentially unnecessary psychological distress and minimise engagement in unnecessary surgery or screening. 相似文献
88.
Dimoska A Butow PN Lynch J Hovey E Agar M Beale P Tattersall MH 《Patient education and counseling》2012,86(2):252-258
Objective
To examine the feasibility and acceptability of routine provision of patient question prompt lists (QPLs) to promote patient participation and patient-clinician communication in medical consultations.Methods
Four cancer centres across NSW, Australia (two rural, two urban) were invited to participate, involving distribution of QPLs to patients seeing a medical or radiation oncologist, or palliative care clinician. Patients rated their satisfaction after their next consultation. Cancer specialists provided their views at the end of the study.Results
Sixty-four percent (389/606) of patients attending consultations received a QPL. Of patients offered a QPL (426), 91% accepted. Of 139 patients surveyed post-consultation, 89% reported reading the QPL and, of these, 44% referred to the QPL during the consultation at least once. All of 10 cancer specialists providing their views post-implementation reported that QPL implementation in routine practice was feasible and did not strain resources.Conclusions
Cancer patients and cancer specialists showed support for routine dissemination of the QPL.Practice implications
For successful implementation of evidence-based tools we recommend promotion by local clinical champions, negotiation with clinic staff about dissemination methods, raised patient awareness through on-site project facilitators, media, consumer and support groups, and availability of resources in hard copy and via online sources. 相似文献89.
Rachel D. Zordan Phyllis N. Butow Laura Kirsten Ilona Juraskova Amanda O’Reilly John Friedsam Nataly Bovopolous Paul Heinrich Margaret Charles Kim Hobbs David Kissane 《Supportive care in cancer》2012,20(3):445-454
Purpose
The literature on cancer support groups supports the provision of ongoing education and training for cancer support group leaders, with evidence suggesting that more skilled and experienced leaders create better outcomes for group members. To address support and training needs reported by leaders, three novel interventions were developed and pilot-tested. These included a leaders' website and discussion forum, DVD and manual, and a 2-day training workshop.Methods
The interventions were developed using a combination of literature review, expert consensus, and consumer feedback. A convenience sample of ten leaders pilot-tested the Website and discussion forum. Using a mixed-method approach, evaluation of the workshop and the DVD and manual was conducted with 35 leaders.Results
Overall, satisfaction with all aspects of the Website and discussion forum was high. Analysis of the quantitative data revealed extremely high satisfaction with the workshop and DVD and manual. The qualitative responses of workshop participants further supported the quantitative findings with enhanced knowledge, understanding, and confidence reported by leaders.Conclusions
All three interventions exhibited a high degree of user acceptance, regardless of the skill or experience of the cancer support group leader. The overall positive findings from the evaluation of the leader Website and discussion forum, the DVD and manual, and the workshop for cancer support group leaders provides evidence to support more rigorous evaluation of these resources in a randomized controlled trial. 相似文献90.
Butow PN Phillips F Schweder J White K Underhill C Goldstein D;Clinical Oncological Society of Australia 《Supportive care in cancer》2012,20(1):1-22