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101.
Wehner Christian Husejnagic Selma Laky Brenda Rausch-Fan Xiaohui Moritz Andreas Haririan Hady 《Clinical oral investigations》2021,25(1):87-94
Clinical Oral Investigations - The aim of this randomized controlled trial was to evaluate the interproximal cleaning efficacy of waist-shaped compared with straight soft interdental brushes in... 相似文献
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Stability of Diagnoses of Cognitive Impairment,Not Dementia in a Veterans Affairs Primary Care Population 下载免费PDF全文
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ObjectiveTo determine the incidence of stillbirth in women who have regular ante-natal ultrasound compared to those that have infrequent scans in a low risk population.ResultsOur study included 23,519 ‘low-risk’ deliveries spanning 2007-2011. This included 2,088 (9%) patients who had frequent ultrasound surveillance and delivery at term and 21,431 (91%) patients who did not. The overall stillbirth rate was 0.34% and 0.20% respectively which was not statistically different (p=0.31).ConclusionThere is no difference in the rate of stillbirth between patients who have more frequent ante-natal ultrasound surveillance compared with those who do not in a low risk population. 相似文献
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Meng Niu Brenda Morsey Benjamin G. Lamberty Katy Emanuel Fang Yu Rosiris Len-Rivera Joan W. Berman Peter J. Gaskill Stephanie M. Matt Pawel S. Ciborowski Howard S. Fox 《Viruses》2020,12(11)
Both substance use disorder and HIV infection continue to affect many individuals. Both have untoward effects on the brain, and the two conditions often co-exist. In the brain, macrophages and microglia are infectable by HIV, and these cells are also targets for the effects of drugs of abuse, such as the psychostimulant methamphetamine. To determine the interaction of HIV and methamphetamine, we isolated microglia and brain macrophages from SIV-infected rhesus monkeys that were treated with or without methamphetamine. Cells were subjected to single-cell RNA sequencing and results were analyzed by statistical and bioinformatic analysis. In the animals treated with methamphetamine, a significantly increased proportion of the microglia and/or macrophages were infected by SIV. In addition, gene encoding functions in cell death pathways were increased, and the brain-derived neurotropic factor pathway was inhibited. The gene expression patterns in infected cells did not cluster separately from uninfected cells, but clusters comprised of microglia and/or macrophages from methamphetamine-treated animals differed in neuroinflammatory and metabolic pathways from those comprised of cells from untreated animals. Methamphetamine increases CNS infection by SIV and has adverse effects on both infected and uninfected microglia and brain macrophages, highlighting the dual and interacting harms of HIV infection and drug abuse on the brain. 相似文献
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Temporal patterns of gene expression in developing maize endosperm identified through transcriptome sequencing 总被引:1,自引:0,他引:1
Guosheng Li Dongfang Wang Ruolin Yang Kyle Logan Hao Chen Shanshan Zhang Megan I. Skaggs Alan Lloyd William J. Burnett John D. Laurie Brenda G. Hunter Joanne M. Dannenhoffer Brian A. Larkins Gary N. Drews Xiangfeng Wang Ramin Yadegari 《Proceedings of the National Academy of Sciences of the United States of America》2014,111(21):7582-7587