全文获取类型
收费全文 | 332篇 |
免费 | 12篇 |
国内免费 | 8篇 |
专业分类
儿科学 | 12篇 |
妇产科学 | 4篇 |
基础医学 | 37篇 |
口腔科学 | 8篇 |
临床医学 | 57篇 |
内科学 | 51篇 |
皮肤病学 | 8篇 |
神经病学 | 7篇 |
特种医学 | 93篇 |
外科学 | 20篇 |
综合类 | 6篇 |
预防医学 | 11篇 |
眼科学 | 1篇 |
药学 | 34篇 |
肿瘤学 | 3篇 |
出版年
2023年 | 1篇 |
2021年 | 4篇 |
2020年 | 3篇 |
2019年 | 5篇 |
2018年 | 4篇 |
2017年 | 4篇 |
2016年 | 6篇 |
2015年 | 6篇 |
2014年 | 10篇 |
2013年 | 8篇 |
2012年 | 10篇 |
2011年 | 9篇 |
2010年 | 23篇 |
2009年 | 11篇 |
2008年 | 8篇 |
2007年 | 12篇 |
2006年 | 14篇 |
2005年 | 9篇 |
2004年 | 4篇 |
2003年 | 4篇 |
2002年 | 2篇 |
2001年 | 3篇 |
2000年 | 2篇 |
1998年 | 18篇 |
1997年 | 19篇 |
1996年 | 13篇 |
1995年 | 11篇 |
1994年 | 13篇 |
1993年 | 13篇 |
1992年 | 2篇 |
1991年 | 4篇 |
1990年 | 3篇 |
1989年 | 9篇 |
1988年 | 8篇 |
1987年 | 6篇 |
1986年 | 10篇 |
1985年 | 6篇 |
1984年 | 3篇 |
1983年 | 2篇 |
1982年 | 7篇 |
1981年 | 2篇 |
1980年 | 8篇 |
1979年 | 5篇 |
1978年 | 3篇 |
1977年 | 7篇 |
1976年 | 7篇 |
1975年 | 9篇 |
1972年 | 2篇 |
排序方式: 共有352条查询结果,搜索用时 8 毫秒
181.
Pien EH; Zeman RK; Benjamin SB; Barth KH; Jaffe MH; Choyke PL; Clark LR; Paushter DM 《Radiology》1985,156(2):329-330
A case of common hepatic duct stricture secondary to hepatic artery chemotherapy infusion is described. CT and endoscopic retrograde cholangiopancreatography (ERCP) may be used in concert to differentiate this entity from other causes of jaundice--namely, hepatic replacement by tumor, porta hepatis adenopathy, and chemotherapy hepatotoxicity. 相似文献
182.
Lack of acute effects of ascorbic acid on spirometry and airway responsiveness to histamine in subjects with asthma 总被引:1,自引:0,他引:1
Jean-Luc Malo M.D. Andr Cartier M.D. Line Pineau R.T. Jocelyne L'Archevêque LR. T. Herberto Ghezzo Ph.D. Richard R. Martin M.D. 《The Journal of allergy and clinical immunology》1986,78(6):1153-1158
Sixteen adult subjects with asthma in a clinical steady state were studied. On day 1, after baseline spirometry, they underwent four histamine inhalation tests with functional recovery between each test. The provocative concentration causing a 20% fall in FEV1 (PC20) was obtained after each test. On days 2, 3, and 4, after baseline spirometry, active and placebo ascorbic acid (2 gm) was administered orally, double-blind, according to a 4.3.1 two-treatment crossover study design. One hour later, spirometry was performed, and PC20 was reassessed. We found no significant changes in FEV1 and FVC after ascorbic acid as compared with placebo administration. There was no difference between PC20 on days 2, 3, and 4 and by standardizing for the four PC20 results obtained on day 1. We conclude that ascorbic acid has no acute bronchodilator effect and does not alter bronchial responsiveness to histamine in subjects with asthma. 相似文献
183.
184.
185.
186.
J Vanagaite Vingen JA Pareja O Støren LR White LJ Stovner 《Cephalalgia : an international journal of headache》1998,18(5):243-249
Quantitative measurement of sound-induced discomfort and pain thresholds showed that migraineurs ( n =65) were significantly more sensitive than headache-free controls ( n =80), both during and outside attack ( p <0.0001). Patients tested with head pain had lower thresholds than those tested without pain ( p <0.01). Migraine with and without aura did not differ as to sound sensitivity. There were no significant differences in thresholds between the symptomatic and nonsymptomatic sides ( p ≥0.78). Patients with unilateral headache or pain of pulsating character were more sensitive than those with bilateral headache or pressing pain ( p <0.05). Phonophobia did not correlate significantly with duration, frequency, or severity of attacks. The main results were in accordance with a questionnaire study concerning subjective evaluation of sound sensitivity Similarities between phonophobia and photophobia in migraine provide evidence that both phenomena share a common pathophysiological mechanism in this condition. 相似文献
187.
188.
189.
190.
Plasmids in bacteria exposed to activated neutrophils mediate mutagenesis when transferred to new hosts 总被引:1,自引:0,他引:1
The plasmid pUC18 contains a lacZ alpha-complementation gene that codes for a small peptide that can complement the delta M15 mutation of the Escherichia coli lacZ (beta-galactosidase) gene, converting bacteria carrying that mutated gene from the lacZ- to the lacZ+ phenotype. This plasmid was used in experiments designed to study mutagenesis by human neutrophils. E coli carrying pUC18 were incubated with neutrophils under conditions in which little ingestion of the bacteria took place; the plasmid was then isolated and transformed into an E coli strain (BOZO) that carries the lacZ delta M15 mutation. Of these transformants, 11 of 205,000 were lacZ, suggesting that in these 11, alpha-complementation had been lost through a mutation. No lac- colonies were detected among several hundred thousand BOZO transformed with plasmid isolated from incubations in which phagocytosis could take place, nor from incubations from which neutrophils were omitted. Despite the lac- phenotype of these 11 transformants, plasmids reisolated from nine of them showed normal alpha-complementing ability when transformed into fresh BOZO. These findings indicated that in these nine, the mutations were located in the chromosomes of the transformed BOZO. It thus appears that on exposure to activated neutrophils, a plasmid may acquire a lesion (? mutation) that can somehow be transferred to the genome of a recipient microorganism, resulting in repair of the damaged plasmid accompanied by mutation of the recipient's chromosome. Restriction mapping of the DNA from four of these nine chromosomal mutants suggested that the mutations did not represent major insertions or deletions in the portion of the bacterial chromosome corresponding to the pUC18 lac operon insert, nor in the remainder of the lacZ delta M15 gene. These results confirm previous work showing that exposure to activated neutrophils can induce mutations in biological systems, and provides an experimental model in which the mechanism of neutrophil-mediated mutagenesis may be examined. 相似文献