Über die ependymalen Mittledorfschen Tumoren

Ohne Zusammenfassung     

Kriegsneurologische Beobachtungen

Ohne ZusammenfassungDer erste der hier besprochenen Fälle wurde auf dem feldärztlichen Abend am 12. IX. 1918 in Udine demonstriert.     

Angiographischer Befund bei Pickscher Atrophie

Ohne Zusammenfassung     

Beiträge zur Rekurrens-Behandlung der progressiven Paralyse

Ohne Zusammenfassung     

Physiological model for distribution of sulfathiazole in swine

A physiological flow model was developed for the distribution of sulfathiazole residues in various tissues in swine. The approach was compartmental, in which the compartments and equilibrium constants had physiological meaning. Differential equations were developed, and appropriate parameter values and initial conditions were substituted and solved by a fourth-order Runga-Kutta technique. Simulation values corresponded with the experimentally determined concentration values in plasma and kidney, liver, muscle, fat, and heart tissues.     

Indomethacin is effective against neurogenic hyperthermia following cranial trauma or brain surgery

The effectiveness of indomethacin treatment (1 mg/kg) as an antipyretic was tested in patients after cranial trauma or brain surgery involving the centromedial forebrain. Indomethacin was effective in reducing temperature in 10 of 11 cases which showed a dipyrone-resistant hyperthermia developing in the first 24 hours after brain damage, while no significant antipyretic effect was seen in hyperthermic cases developing more than 72 hours after cranial trauma or brain surgery. Biochemical tests estimating the effect of indomethacin, and pyrazolone derivatives on the arachidonic acid metabolism showed significant effects of indomethacin only in influencing cyclooxygenase activity and no effect of any drugs on lipoxygenase actions. In view of these observations, the use of indomethacin is recommended as a treatment for neurogenic hyperthermia.