关节镜下与切开复位Herbert钉内固定治疗桡骨小头骨折短期疗效比较

目的 比较关节镜下与切开复位Herbert钉内固定治疗桡骨小头骨折的短期临床疗效.方法 采用回顾性病例对照研究分析2017年1月至2018年12月上海中冶医院收治的38例单侧桡骨小头骨折(Mason Ⅱ型)患者的临床资料,其中男22例,女16例;年龄20～65岁[(37.4±12.6)岁].20例采用关节镜下复位Her...     

骨折相关感染治疗的研究进展

骨折相关感染(FRI)是骨科常见的手术并发症,FRI发生的多样性以及近年来对抗生素的滥用给FRI的诊断和治疗带来了一定难度.术前体格检查、影像学检查及相关的实验室检查对明确诊断具有重要意义.治疗方法主要以静脉应用抗生素、局部清创、术中植入抗生素载体为主,目前临床应用效果最好且满意度较高的是术中植入抗生素载体,其具有较好...     

空心钉联合内侧支撑钢板术治疗中青年PauwelsⅢ型股骨颈骨折的疗效

目的 观察空心钉联合内侧支撑钢板术治疗中青年PauwelsⅢ型股骨颈骨折的临床疗效.方法 回顾性分析2016年12月—2018年3月河南省洛阳正骨医院髋部损伤科收治PauwelsⅢ型股骨颈骨折中青年患者74例,按手术方式不同分为对照组和观察组,各37例.观察组行空心螺钉联合内侧支撑钢板术治疗,男性17例,女性20例;年...     

皮瓣移植修复躯干部慢性放射性溃疡疗效观察

目的 总结、探讨轴型肌皮瓣及穿支皮瓣在躯干部慢性放射性溃疡中的应用体会.方法 对2019年1月至2019年12月北京积水潭医院烧伤科收治的13例躯干部慢性放射性溃疡患者实施外科清创后应用腹直肌肌皮瓣、背阔肌肌皮瓣及肋间动脉穿支皮瓣进行修复,观察治疗效果.结果 13例患者中行纵行腹直肌肌皮瓣修复者6例、背阔肌肌皮瓣修复者...     

Quantitative Evaluation of Gastrocnemius Medialis Stiffness During Passive Stretching Using Shear Wave Elastography in Patients with Parkinson's Disease: A Prospective Preliminary Study

ObjectiveTo prospectively investigate the feasibility of shear wave elastography (SWE) as a new quantitative and objective method for evaluating the stiffness of the gastrocnemius medialis (GM) muscle during passive stretching in patients with Parkinson''s disease (PD).Materials and MethodsSWE of the GM muscle was performed in 28 patients with PD [13 female and 15 male; mean age ± standard deviation (SD): 63.0 ± 8.5 years] and 12 healthy controls (5 female and 7 male; mean age ± SD: 59.3 ± 6.4 years) during passive ankle rotation. A Young''s modulus-ankle angle curve was constructed. The GM slack angle and baseline Young''s modulus (E₀) were compared between the markedly symptomatic and mildly symptomatic sides of patients with PD, and healthy controls. Additionally, the correlation between the GM slack angle and the severity of rigidity, and the observer reproducibility of SWE in determining the GM slack angle were evaluated.ResultsThe GM slack angle was smaller on both the markedly and mildly symptomatic sides in patients with PD than in healthy controls (mean ± SD of −29.13° ± 3.79° and −25.65° ± 3.39°, respectively, vs. −21.22° ± 3.52°; p < 0.001 and p = 0.006, respectively). Additionally, in patients with PD, the GM slack angle on the markedly symptomatic side was smaller than that on the mildly symptomatic side (p = 0.003). The E₀ value was lower on both the markedly and mildly symptomatic sides in patients with PD than in healthy controls (mean ± SD of 10.11 ± 2.85 kPa and 10.08 ± 1.88 kPa, respectively, vs. 12.23 ± 1.02 kPa; p = 0.012 and p < 0.001, respectively). However, no significant difference was found between the markedly and mildly symptomatic sides in patients with PD (p = 0.634). A negative linear relationship was observed between the GM slack angle and lower limb rigidity score on the markedly symptomatic side in patients with PD (r = −0.719; p < 0.001). The intraclass correlation coefficients for observer reproducibility of SWE ranged from 0.880 to 0.951.ConclusionThe slack angle determined by SWE may be a useful quantitative and reproducible method for evaluating muscle stiffness in patients with PD.     

Relationship between ADAMTS4 and carotid atherosclerotic plaque vulnerability in humans

Background

Rupture of atherosclerotic plaques and the resulting thrombosis are vital causes of clinical ischemic events. Recent studies have shown that ADAMTS4 (a disintegrin and metalloproteinase with thrombospondin motifs 4) is a pathogenic factor of plaque vulnerability in mice. However, the relationship between ADAMTS4 and carotid atherosclerotic vulnerable plaques in humans remains unclear.

The diagnosis and staging of pancreatic cancer: A comparison of endoscopic ultrasound and computed tomography with pancreas protocol

Background

Pancreatic cancer is the fourth leading cause of cancer-related death in United States. We compared Computed Tomography (CT) with pancreas protocol and Endoscopic Ultrasound (EUS) in terms of mass detection, mass size, vascular involvement and lymph node involvement.

腹膜透析患者血清白蛋白与体液负荷的关系

目的:血清白蛋白是影响透析患者预后的重要危险因素之一,而且与新发生及复发的心血管并发症及死亡率关系密切。近年发现低白蛋白血症可能更多与容量负荷过度及炎症等有关。因此,拟对腹膜透析患者中血清白蛋白与体液负荷的关系进行分析。方法:对CAPD患者,实行限制水钠摄入治疗2个月,测定患者治疗前后的体重、容量指标及血清白蛋白水平,收集患者治疗前后血压、24h尿量和超滤量等相关资料。结果:CAPD患者35例。经严格的控制水钠摄入治疗后,有26名患者体重明显减轻,从(62.2±8.8)kg减至(60.2±8.2)kg(P=0.000),细胞外液(ECW)从(16.23±2.95)L降至(14.96±2.64)L(P=0.000),而血清白蛋白水平则从(34.9±3.5)g/L升高到(37.3±3.7)g/L(P=0.003),患者自我感觉明显改善;9名患者体重无改善,平均增加(1.1±1.1)kg,ECW增加(0.68±1.28)L,血清白蛋白降低(2.1±2.3)g/L;所有患者24小时尿量和超滤量没有统计学意义上的差别。血清白蛋白变化与各项容量指标的变化间均存在线性相关(P<0.05)。结论:血清白蛋白的变化与患者体液状况的变化显著负相关。严格控制患者的水钠摄入是控制患者容量负荷过多、提高血清白蛋白水平的有效方法,患者对水钠控制的依从性将影响治疗的效果。