Embolic Control of Massive Haematobilia After Liver Biopsy

Life threatening haematobilia following liver biopsy was successfully treated by percutaneous transcatheter embolization of the right hepatic artery. Complications of liver biopsy and aspects of their treatment are discussed.     

The release of β glucuronidase from leukocytes in the presence of immune complexes

The lysosomal enzyme beta glucuronidase was selectively released from leukocytes when these were incubated with insoluble immnue complexes and also from the leukocytes of patients with immune complex disease when these were incubated with their own plasma.     

BLACK PIGMENT STONE IN A MALE CHILD AGED TWO YEARS AND SEVEN MONTHS

A case of cholelithiasis is reported occurring in a boy aged two years and seven months. The patient presented with biliary colic, and cholecystectomy was performed. Detailed analysis of the stone, including electron-probe studies, showed it to be an example of a polybilirubinate stone, containing also calcium, carbonate, and phosphate, with some sulphur, sodium, and magnesium. There were also traces of chlorine, aluminium, copper, nickel, and manganese.     

ENDOMETRIOSIS OF THE SIGMOID COLON AND RECTUM

Endometriosis is a common disease of women which occasionally causes serious symptoms in virtue of involvement of the distal large intestine. Two cases are reported, illustrating opposite ends of the spectrum of this disorder, one presenting with a complete large-bowel obstruction, and the other with periodical per-rectal bleeding. Endometriosis in these locations can closely mimic carcinoma, and from a consideration of our cases and the literature, those features which might help to distinguish one from the other are discussed. The treatment of endometriosis itself is briefly outlined. Either to avoid unnecessarily radical surgery, or to plan appropriate specific treatment at the time of surgery for the colorectal lesion, a preoperative diagnosis is desirable, but it Is unlikely unless the clinician is aware of this unusual form of endometriosis.     

The etiology of chronic otitis media*

Various current theories regarding the aetiology of chronic otitis media are considered in detail. The concept that it originates from an acute middle ear infection no longer appears tenable. Recent experimental work has demonstrated the role of invading skin causing invasive osteitis. It is postulated that in some instances osteitis may follow erosion of the meatal skin and proceed to widespread chronic disease of the temporal bone. The important difference between obstruction and inadequacy of the Eustachian tube and the significance of the latter in chronic middle ear disease is emphsized. The Eustachian mechanism of cholesteatoma formation may best be studied by observing the development of retraction pockets following tympanoplasty.     

Superoxide dismutase gene expression and activity in the brain of spontaneously hypertensive rats and normotensive rats

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A comparison of bonfils fiberscope‐assisted laryngoscopy and standard direct laryngoscopy in simulated difficult pediatric intubation: a manikin study

Introduction: Difficult airway management in children is challenging. One alternative device to the gold standard of direct laryngoscopy is the STORZ Bonfils fiberscope (Karl Storz Endoscopy, Tuttlingen, Germany), a rigid fiberoptic stylette‐like scope with a curved tip. Although results in adults have been encouraging, reports regarding its use in children have been conflicting. We compared the effectiveness of a standard laryngoscope to the Bonfils fiberscope in a simulated difficult infant airway. Methods: Ten pediatric anesthesiologists were recruited for this study and asked to perform three sets of tasks. For the first task, each participant intubated an unaltered manikin (SimBaby ^TM, Laerdal, Puchheim, Germany) five times using a styletted 3.5 endotracheal tube (ETT) and a Miller 1 blade (group DL‐Normal). For the second task, a difficult airway configuration simulating a Cormack‐Lehane grade 3B view was created by fixing a Miller‐1 blade into position in the manikin using a laboratory stand. Each participant then intubated the manikin five times with a styletted 3.5 ETT using conventional technique but without touching the laryngoscope (group DL‐Difficult). In the third task, the manikin was kept in the same difficult airway configuration, and each participant intubated the manikin five times using a 3.5‐mm ETT mounted on the Bonfils fiberscope as an adjunct to direct laryngoscopy with the Miller‐1 blade (group BF‐Difficult). Primary outcomes were time to intubate and success rate. Results: A total of 150 intubations were performed. Correct ETT placement was achieved in 100% of attempts in group DL‐Normal, 90% of attempts in group DL‐Difficult and 98% of attempts in BF‐Difficult. Time to intubate averaged 14 s (interquartile range 12–16) in group DL‐Normal; 12 s (10–15) in group DL‐Difficult; and 11 s (10–18) in group BF‐Difficult. The percentage of glottic opening seen (POGO score) was 70% (70–80) in group DL‐Normal; 0% (0–0) in group DL‐Difficult; and 100% (100–100) in group BF‐Difficult. Discussion: The Bonfils fiberscope‐assisted laryngoscopy was easier to use and provided a better view of the larynx than simple direct laryngoscopy in the simulated difficult pediatric airway, but intubation success rate and time to intubate were not improved. Further studies of the Bonfils fibrescope as a pediatric airway adjunct are needed.