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Pathology of Streptococcal meningitis following intravenous intracisternal and natural routes of infection 总被引:1,自引:0,他引:1
The distribution of pathological lesions present in 20 cases of naturally-occurring Streptococcus suis type 2 meningitis and 20 cases of the disease induced experimentally by intravenous or intracisternal inoculation was examined. It was found that the distribution of lesions was similar; mild lesions were present at the choroid plexuses whilst the most dense cellular accumulations were found at sites of cerebrospinal fluid (CSF) efflux, such as arachnoid villi and olfactory nerve sheaths. The distribution of changes was considered to reflect the dynamics of CSF flow rather than indicate the site of entry of the organisms into the CSF compartment. 相似文献
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BLAKEMORE AH 《Annals of surgery》1948,128(4):825-841
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Serological markers of hepatitis B in patients with alcoholic liver disease: a multi-centre survey 总被引:5,自引:3,他引:2
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In a study of 195 patients derived from five centres in northern Britain and with histologically confirmed alcoholic liver disease we have found an increased prevalence of serological markers of hepatitis B. This increased prevalence was found in each of the five centres; the overall frequency ranged from 11% sero-positivity in fatty liver, 12% in alcoholic hepatitis and 27% in cirrhosis. 相似文献
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Fish C.J. & Blakemore W.F. (1983) Neuropathology and Applied Neurobiology 9 , 109–120
A model of chronic spinal cord compression in the cat
An experimental method of producing chronic compression of the cat spinal cord is described. A ligature placed around the lumbar spinal cord of 3-month-old kittens restricts the growth of the spinal cord to produce compression with a slow onset and an insidious progression. The methods of following the clinical progress of affected animals and of sampling the spinal cord after perfusion fixation are presented. The sampling method used allowed analysis of the three dimensional distribution of the pathological changes caused by the compression. These changes were not symmetrically distributed: the spinal cord caudal to the ligature became swollen and extensive partial demyelination occurred under the ligature and caudal to it, in the swollen region of the cord, whereas cranial to the ligature there was only minimal damage. It is concluded that the method produces a useful model of chronic compression of the spinal cord, which will be of value in studying partial demyelination. 相似文献
A model of chronic spinal cord compression in the cat
An experimental method of producing chronic compression of the cat spinal cord is described. A ligature placed around the lumbar spinal cord of 3-month-old kittens restricts the growth of the spinal cord to produce compression with a slow onset and an insidious progression. The methods of following the clinical progress of affected animals and of sampling the spinal cord after perfusion fixation are presented. The sampling method used allowed analysis of the three dimensional distribution of the pathological changes caused by the compression. These changes were not symmetrically distributed: the spinal cord caudal to the ligature became swollen and extensive partial demyelination occurred under the ligature and caudal to it, in the swollen region of the cord, whereas cranial to the ligature there was only minimal damage. It is concluded that the method produces a useful model of chronic compression of the spinal cord, which will be of value in studying partial demyelination. 相似文献
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