全文获取类型
收费全文 | 6365篇 |
免费 | 378篇 |
国内免费 | 46篇 |
专业分类
耳鼻咽喉 | 29篇 |
儿科学 | 157篇 |
妇产科学 | 168篇 |
基础医学 | 1032篇 |
口腔科学 | 80篇 |
临床医学 | 528篇 |
内科学 | 1626篇 |
皮肤病学 | 279篇 |
神经病学 | 592篇 |
特种医学 | 149篇 |
外科学 | 514篇 |
综合类 | 11篇 |
一般理论 | 2篇 |
预防医学 | 376篇 |
眼科学 | 109篇 |
药学 | 400篇 |
中国医学 | 26篇 |
肿瘤学 | 711篇 |
出版年
2024年 | 6篇 |
2023年 | 55篇 |
2022年 | 152篇 |
2021年 | 220篇 |
2020年 | 123篇 |
2019年 | 181篇 |
2018年 | 208篇 |
2017年 | 136篇 |
2016年 | 159篇 |
2015年 | 209篇 |
2014年 | 276篇 |
2013年 | 324篇 |
2012年 | 479篇 |
2011年 | 547篇 |
2010年 | 300篇 |
2009年 | 250篇 |
2008年 | 423篇 |
2007年 | 399篇 |
2006年 | 437篇 |
2005年 | 381篇 |
2004年 | 357篇 |
2003年 | 308篇 |
2002年 | 292篇 |
2001年 | 35篇 |
2000年 | 24篇 |
1999年 | 43篇 |
1998年 | 59篇 |
1997年 | 59篇 |
1996年 | 49篇 |
1995年 | 47篇 |
1994年 | 33篇 |
1993年 | 31篇 |
1992年 | 22篇 |
1991年 | 25篇 |
1990年 | 19篇 |
1989年 | 21篇 |
1988年 | 14篇 |
1987年 | 10篇 |
1986年 | 11篇 |
1985年 | 6篇 |
1984年 | 9篇 |
1983年 | 4篇 |
1981年 | 5篇 |
1980年 | 4篇 |
1978年 | 3篇 |
1977年 | 5篇 |
1969年 | 5篇 |
1968年 | 6篇 |
1966年 | 3篇 |
1909年 | 2篇 |
排序方式: 共有6789条查询结果,搜索用时 0 毫秒
1.
Exhaled nitric oxide in children with allergic rhinitis: A potential biomarker of asthma development 下载免费PDF全文
2.
3.
4.
5.
Rebecca Voltan Arianna Castaldello Egidio Brocca-Cofano Rita De Michele Chiara Triulzi Giuseppe Altavilla Luisa Tondelli Michele Laus Katia Sparnacci Eva Reali Riccardo Gavioli Barbara Ensoli Antonella Caputo 《Vaccine》2009
Cationic block copolymers spontaneously assemble via electrostatic interactions with DNA molecules in aqueous solution giving rise to micellar structures that protect the DNA from enzymatic degradation both in vitro and in vivo. In addition, we have previously shown that they are safe, not immunogenic and greatly increased antigen-specific CTL responses following six intramuscular inoculations of a very low dose (1 μg) of the vaccine DNA as compared to naked DNA. Nevertheless, they failed to elicit detectable humoral responses against the antigen. To gain further insight in the potential application of this technology, here we show that a shorter immunization protocol based on two DNA intramuscular inoculations of 1 μg of DNA delivered by these copolymers and a protein boost elicits in mice broad (both humoral and cellular) and long-lasting responses and increases the antigen-specific Th1-type T cell responses and CTLs as compared to priming with naked DNA. These results indicate that cationic block copolymers represent a promising adjuvant and delivery technology for DNA vaccination strategies aimed at combating intracellular pathogens. 相似文献
6.
Uta Kraus-Tiefenbacher Lelia Bauer Antonella Scheda Carola Schoeber Joerg Schaefer Volker Steil Frederik Wenz 《BMC cancer》2007,7(1):178
Background
For patients suffering of recurrent breast cancer within the irradiated breast, generally mastectomy is recommended. The normal tissue tolerance does not permit a second full-dose course of radiotherapy to the entire breast after a second breast-conserving surgery (BCS). A novel option is to treat these patients with partial breast irradiation (PBI). This approach is based on the hypothesis that re-irradiation of a limited volume will be effective and result in an acceptable frequency of side effects. The following report presents a single center experience with intraoperative radiotherapy (IORT) during excision of recurrent breast cancer in the previously irradiated breast. 相似文献7.
Maria Cristina Locatelli Lucilla Tedeschi Maurizia Clerici Antonella Romanelli Adelaide D'Antona Roberto Labianca Gino Luporini 《Supportive care in cancer》1996,4(3):218-219
We have reviewed the incidence of cisplatin-induced anaemia in patients affected with solid tumours treated with at least three courses of first-line cisplatincontaining regimens. In our experience, a low percentage (5%) of patients required transfusions of red blood cells. We think it is of the utmost importance to adopt uniform criteria in monitoring and treatment of patients at risk of developing cisplatin anaemia and to identify subsets of patients to eventually treat with erythropoietin. 相似文献
8.
Antonio Amoroso Pierluigi Garzia Marta Vadacca Sara Galluzzo Flavia Del Porto Anna P Mitterhofer Antonella Afeltra 《The Journal of adolescent health》2003,32(1):94-97
We report on a 26-year-old female affected by Noonan syndrome (NS), a congenital disorder characterized by various phenotypic features and congenital anomalies) associated with a variety of autoimmune diseases, including systemic lupus erythematosus, celiac disease, and Hashimoto thyroiditis. Autoimmunity is seldom described in NS and the association between this congenital disease and three autoimmune disorders has not been previously reported. Should the occurrence of autoimmune disorders in NS be confirmed, a relevant clinical and laboratory evaluation of NS patients should be performed in order to clarify whether the immune system involvement represents only an occasional event or is a feature of the disease. 相似文献
9.
10.
Fabio Ghezzi Maurizio Serati Antonella Cromi Stefano Uccella Stefano Salvatore Paola Triacca Pierfrancesco Bolis 《International urogynecology journal》2006,17(4):335-339
The purpose of this study was to evaluate the outcome of tension-free vaginal tape (TVT) procedure in women with urodynamic stress incontinence diagnosed as having intrinsic sphincteric deficiency (ISD). The combination of a maximal urethral closure pressure <20 cm H2O and a Valsalva leak point pressure <60 cm H2O was considered as diagnostic of ISD. Subjects with detrusor overactivity on preoperative urodynamics were excluded. A total of 35 patients with both low closure pressure and leak point pressure were enrolled. Bladder perforation occurred in three (8.6%) cases. Postoperative urinary voiding difficulties occurred in nine (25.7%) women. Two patients underwent surgical detension of the tape, with complete resolution of urinary retention and no relapse of incontinence. Women with postoperative voiding dysfunction had a significantly lower detrusorial pressure at the peak flow on preoperative urodynamics compared to those who voided efficiently after TVT. The mean (range) follow-up time was 12.5 months (3–36). The objective cure rate for stress incontinence was 91.4%. Two of the three (66%) patients in whom the TVT procedure failed had a fixed urethra. De novo urge incontinence was found in five (14.3%) patients. 相似文献