Social Factors Associated with Readiness for Sexual Activity in Adolescents: A Population-Based Cohort Study

Archives of Sexual Behavior - Various factors are associated with sexual activity in adolescence and it is important to identify those that promote healthy and adaptive romantic and sexual...     

Efficacy of Heat Treatment of Factor VIII Concentrate

Two batches of heat-treated factor VIII concentrate were found to contain anti-HIV-positive plasma donations. The batches were dry-heat-treated at 68 degrees C for 2 and 24 h, respectively. No HIV seroconversions occurred in 13 susceptible haemophiliacs receiving a total of 540 bottles of these factor VIII preparations.     

The effect of astaxanthin supplementation on performance and fat oxidation during a 40 km cycling time trial

ObjectivesThis study aimed to investigate whether supplementation with 12 mg?day^?1 astaxanthin for 7 days can improve exercise performance and metabolism during a 40 km cycling time trial.DesignA randomised, double-blind, crossover design was employed.MethodsTwelve recreationally trained male cyclists (VO_2peak: 56.5 ± 5.5  mL?kg^?1?min^?1, W_max: 346.8 ± 38.4  W) were recruited. Prior to each experimental trial, participants were supplemented with either 12 mg?day^?1 astaxanthin or an appearance-matched placebo for 7 days (separated by 14 days of washout). On day 7 of supplementation, participants completed a 40 km cycling time trial on a cycle ergometer, with indices of exercise metabolism measured throughout.ResultsTime to complete the 40 km cycling time trial was improved by 1.2 ± 1.7% following astaxanthin supplementation, from 70.76 ± 3.93 min in the placebo condition to 69.90 ± 3.78 min in the astaxanthin condition (mean improvement = 51 ± 71 s, p = 0.029, g = 0.21). Whole-body fat oxidation rates were also greater (+0.09 ± 0.13 g?min^?1, p = 0.044, g = 0.52), and the respiratory exchange ratio lower (?0.03 ± 0.04, p = 0.024, g = 0.60) between 39–40 km in the astaxanthin condition.ConclusionsSupplementation with 12 mg?day^?1 astaxanthin for 7 days provided an ergogenic benefit to 40 km cycling time trial performance in recreationally trained male cyclists and enhanced whole-body fat oxidation rates in the final stages of this endurance-type performance event.     

Long-term serological follow-up after primary Coxiella burnetii infection in patients with vascular risk factors for chronic Q fever

We evaluated the long-term serological follow-up of patients with vascular risk factors for chronic Q fever that were previously Coxiella burnetii seropositive. C. burnetii phase I IgG titers were reevaluated in patients that gave informed consent or retrospectively collected in patients already deceased or lost to follow-up. Of 107 patients, 25 (23.4%) became seronegative, 77 (72.0%) retained a profile of past resolved Q fever infection, and five (4.7%) developed chronic Q fever. We urge clinicians to stay vigilant for chronic Q fever beyond two years after primary infection and perform serological testing based on clinical presentation.