Sclerosing stromal tumor of the ovary in a 30-year-old woman. A case report and review of the literature

Sclerosing stromal tumor of the ovary (SST) is an extremely rare neoplasm occurring predominantly in the second and third decades of life. It is a distinct benign neoplasm that differs from fibromas, thecomas, luteinized tumors and lipoid cell tumors. It presents most often with non-specific symptoms. We describe the case of a 30-year-old woman who developed menstrual irregularities and pelvic pain. She was diagnosed and treated operatively at our Department. During surgery, a benign tumor was found in the right ovary. Light microscopic and ultrastructural study confirmed the diagnosis of sclerosing stromal tumor of the ovary.     

Pulsed dose brachytherapy--a review of clinical applications in the treatment of gynecological malignancies

Pulsed Dose Rate (PDR) treatment is a new brachytherapy modality that combines physical advantages of High-Dose-Rate (HDR) technology (isodose optimization, radiation safety) with the radiobiological advantages of Low-Dose-Rate (LDR) brachytherapy. Pulsed brachytherapy consists of using a stronger radiation source than for LDR brachytherapy and is giving a series of short exposures of 10 to 30 minutes in every hour to approximately the same total dose in the same overall as with the LDR. Modern afterloading equipment offers some advantages over interstitial or intracavitary insertion of separate needles, tubes, seeds or wires. Isodose volumes in tissue can be created flexibly by a combination of careful placement of the catheter and adjustment of the dwell times of the computerized stepping source. Automatic removal of the radiation sources into a shielded safe eliminates radiation exposures to staff and visitors. Radiation exposure is also eliminated to the staff who formerly loaded and unloaded a multiplicity of radioactive sources into the catheters, ovoids, tubes etc. This retrospective study based on summarized clinical investigations analyses the feasibility, reasons for introducing PDR brachytherapy, preliminary results of PDR brachytherapy in treatment of gynecological malignancies and proposed treatment schema.     

The mode of anaesthesia for caesarean section in the opinion of pregnant and delivering women

OBJECTIVES: Conduction anaesthesia is regarded as a very safe method for the mother and for a newborn. This kind of anaesthesia reduces the risk of gastric contents aspiration and does not cause the respiratory depression. However in every case it is essential to take into consideration the woman's opinion, for whom delivering of the child is the particularly important event. DESIGN: The aim of the study was the evaluation the presence and the intensification grade of side effects of the anaesthesia to the caesarean section and establishing, which kind of anaesthesia to this operation: general or conduction is assessed as the best method for the delivering women. RESULTS: In study group among 76 women after cesarean section were 49 (64.5%) after epidural anaesthesia, 22 women (28.9%)--after spinal anaesthesia, and 5 patients (6.6%) were operated in general anaesthesia. The most common side effects after anaesthesia for cesarean section were: weakness and backache. After POP the headache was much more often symptom. CONCLUSIONS: Most of pregnant women preferred epidural anaesthesia during delivering of the child by caesarean section.     

Effective Smoking Intervention During Pregnancy

ABSTRACT: About one-third of women enter their pregnancies as smokers. Attempts to help those who do not quit on their own have not been effective. As part of a 3-year study to test the hypothesis that smoking reduction during pregnancy improves the birthweight of the infant (an hypothesis which was confirmed), a smoking intervention program was developed that resulted in a twofold increase in the percentage of women who stopped smoking cigarettes during their pregnancy. There was no comparative evaluation of the different kinds of intervention activities that were used, but because they were successful in the aggregate, they are described here and a judgment made of the effectiveness of the different components. The main method of contact for the counseling was a single face-to-face session at the smoker's home, followed by frequent phone contacts. Although information was given on the risks of smoking during pregnancy, the emphasis was on how to stop through the use of behavioral skills such as developing commitment, self-monitoring, stimulus control, substitute and incompatible behaviors, and positive associations with not smoking. A series of contacts through mailed information was maintained throughout the pregnancy. The findings have implications for strengthening the intervention activities that are presently offered to pregnant smokers.     

Disseminate cerebral gliomatosis with fibrillary degeneration of the glia and with rosenthal fibres

Summary An unusual case of disseminate cerebral gliomatosis is reported. Numerous blastomatous foci distributed within the white matter of both hemispheres, showed annular arrangement around the plaques of uncomplete demyelinisation and fibrous gliosis; these foci contained Rosenthal fibres as well as glial cells, showing in their cytoplasm peculiar changes called by the author gliofibrillary degeneration. The nature of the reported process is discussed.

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Zusammenfassung Ein ungewöhnlicher Fall von disseminierter cerebraler Sklerose wird beschrieben. Zahlreiche blastomatöse, im Markweiß beider Hemispheren verteilte Herde zeigten um die Plaques ringförmig angeordnete, unvollständige Entmarkung und Fasergliose; diese Herde enthielten Rosenthalsche Fasern und Gliazellen, die in ihrem Cytoplasma eigenartige, vom Autor als gliofibrilläre Degeneration bezeichnete Veränderungen aufweisen. Die Wesensart des dargestellten Prozesses wird diskutiert.

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With 7 Figures in the Text