全文获取类型
收费全文 | 48976篇 |
免费 | 3185篇 |
国内免费 | 188篇 |
专业分类
耳鼻咽喉 | 524篇 |
儿科学 | 1231篇 |
妇产科学 | 859篇 |
基础医学 | 6401篇 |
口腔科学 | 1252篇 |
临床医学 | 4759篇 |
内科学 | 9953篇 |
皮肤病学 | 725篇 |
神经病学 | 4797篇 |
特种医学 | 2551篇 |
外国民族医学 | 6篇 |
外科学 | 7212篇 |
综合类 | 593篇 |
一般理论 | 40篇 |
预防医学 | 4025篇 |
眼科学 | 1199篇 |
药学 | 2928篇 |
中国医学 | 69篇 |
肿瘤学 | 3225篇 |
出版年
2023年 | 206篇 |
2022年 | 348篇 |
2021年 | 808篇 |
2020年 | 612篇 |
2019年 | 810篇 |
2018年 | 953篇 |
2017年 | 773篇 |
2016年 | 915篇 |
2015年 | 1052篇 |
2014年 | 1472篇 |
2013年 | 2044篇 |
2012年 | 3103篇 |
2011年 | 3286篇 |
2010年 | 1866篇 |
2009年 | 1712篇 |
2008年 | 3056篇 |
2007年 | 3149篇 |
2006年 | 3104篇 |
2005年 | 3038篇 |
2004年 | 2843篇 |
2003年 | 2762篇 |
2002年 | 2655篇 |
2001年 | 614篇 |
2000年 | 567篇 |
1999年 | 634篇 |
1998年 | 602篇 |
1997年 | 469篇 |
1996年 | 421篇 |
1995年 | 402篇 |
1994年 | 323篇 |
1993年 | 292篇 |
1992年 | 370篇 |
1991年 | 338篇 |
1990年 | 310篇 |
1989年 | 326篇 |
1988年 | 296篇 |
1987年 | 308篇 |
1986年 | 280篇 |
1985年 | 301篇 |
1984年 | 306篇 |
1983年 | 294篇 |
1982年 | 320篇 |
1981年 | 297篇 |
1980年 | 263篇 |
1979年 | 227篇 |
1978年 | 234篇 |
1977年 | 195篇 |
1976年 | 168篇 |
1975年 | 177篇 |
1974年 | 183篇 |
排序方式: 共有10000条查询结果,搜索用时 0 毫秒
81.
Pierre-Michel Cahen Jean-Christophe Turlot Robert M. Frank Gérard Clement Gil Seckler 《Community dentistry and oral epidemiology》1987,15(4):211-215
A representative sample of 1650 children randomly selected in the 6-15-yr-old schoolchild population of Strasbourg was examined by well-calibrated examiners. The prevalence of caries was determined with the DMFT, DMFS and dft indices using bitewing radiographs. Plaque, calculus and gingival indices were also determined. The results obtained were compared with the initial study of 1974 performed in Strasbourg using the same epidemiologic methods. Whereas no important variations were observed in caries prevalence of primary teeth, a significant reduction of caries activity was observed in DMFT and DMFS indices in all age groups. There was a reduction of these two indices of respectively 32% and 33% in the 12-yr-old children. The reduction was the most significant on approximal surface lesions. A statistically significant decrease of the calculus and gingival indices was also observed between 1974 and 1984. A less significant decrease was observed for the plaque index. 相似文献
82.
W Frank R Karlstadt F Rockhold R Palmer M Malone M Young 《Clinical pharmacology and therapeutics》1989,46(2):234-239
The relative effectiveness of intermittent infusions and primed continuous infusions of cimetidine in the maintenance of intragastric pH greater than or equal to 4.0 was evaluated in a double-blind crossover trial in 26 patients who had active or healed gastroduodenal ulcers. During the intermittent phase, each patient received 300 mg cimetidine intravenously every 6 hours. During the continuous infusion phase, each patient was given a continuous infusion of 37.5 mg cimetidine per hour, preceded by a priming dose of 300 mg cimetidine that was given for 15 minutes. Intragastric pH was monitored continuously. During the last 12 hours of the study, the continuous infusion regimen provided 20% more time in which the pH was more [corrected] than 4.0 with 25% less medication than did the intermittent infusion regimen. 相似文献
83.
Hamid R Djalilian Khashayar Lessan Vahid Grami Stefan E Pambuccian Stephen R Spellman Walter C Low Walter A Hall Frank G Ondrey 《Otolaryngology--head and neck surgery》2004,131(5):781-783
OBJECTIVES: To develop an immune-competent animal model for mucosally derived squamous cell carcinoma (SCCA). STUDY DESIGN: Fifteen Fischer 344 rats were inoculated with 1, 2, 5, 10, or 20 x 10(6) FAT7 cells in their flanks. The animals were observed for tumor growth and metastasis. RESULTS: All animals developed tumors that grew exponentially. Pulmonary metastases developed in all animals and 13% developed lymph node metastases. CONCLUSION: The FAT7 flank tumor in Fischer 344 rats is a new animal model that closely resembles the behavior of human mucosal head and neck cancer. SIGNIFICANCE: The existence of an immune-competent, mucosally derived, and reliable animal model of SCCA that somewhat resembles human head and neck SCCA gives the opportunity to perform immune-modulating experiments on head and neck cancer in these animals. EBM rating: B-3. 相似文献
84.
Harvey A Ziessman Frederic H Fahey Frank B Atkins Jonathan Tall 《Journal of nuclear medicine》2004,45(5):760-764
The purposes of this investigation were to standardize and validate a simple quantitative method for performing radionuclide solid gastric emptying that can be used for any dual-head gamma-camera and to establish reference values. METHODS: After eating a solid meal (egg sandwich) labeled with a radionuclide, 20 healthy volunteers (9 male, 11 female) underwent a 90-min gastric-emptying study performed with a triple-head gamma-camera. Two sets of 3 simultaneous projections were acquired sequentially for 30 s each: anterior, right posterior oblique (RPO), left posterior oblique (LPO), posterior, left anterior oblique (LAO), and right anterior oblique (RAO), and this sequence was repeated continuously for 90 min. Time-activity curves were generated using a gastric region of interest for each of the views as well as the conjugate-view geometric mean (GM) data for the anterior/posterior, LAO/RPO, and RAO/LPO combinations. Quantitative parameters were determined: percentage gastric emptying (%GE) at 90 min, half-time (min) based on an exponential fit, and clearance rate (%/min) based on a linear fit. Reference values were determined on the basis of a 95% confidence interval of the t distribution. The results were statistically analyzed and compared. RESULTS: The %GE reference values were greater for the anterior/posterior GM (>or=33%) than for the LAO (>or=31%) and anterior (>or=30%) GMs. The 3 %GE GM methods, the 3 exponential-fit GM methods, and the 3 linear-fit GM methods had high correlation coefficients (r >or= 0.874), and with only a single exception, there was no statistical difference among them. The LAO method and LAO/RPO GM mean method correlated strongly (r = 0.900) and had similar mean values (52% vs. 51%) and reference values (29% vs. 30%). All 3 methods of GM quantification also correlated strongly, and there was no significant difference among them. CONCLUSION: We have described and validated a simple method for radionuclide solid gastric emptying that can be used with a dual-head gamma-camera. We recommend the anterior/posterior GM method and have established reference values (>or=33%). 相似文献
85.
Hepatocyte isolation from pig livers after warm ischaemic injury 总被引:9,自引:0,他引:9
Michael R. Schön Gero Puhl Jörg Gerlach Jorn Frank Peter Neuhaus 《Transplant international》1994,7(S1):159-162
Abstract Hepatocyte cultures have been used extensively for a wide variety of physiological, pharmacological and experimental studies. The warm ischaemic period before isolation is kept to a minimum to achieve a high yield of cells isolated and a good viability for culture. We have recently introduced a new concept of liver resuscitation after warm ischaemia that is based on a 3-h reperfusion period with an improved perfusate and simultaneous dialysis. In this study, we applied the new technique for hepatocyte isolation from livers subjected to 80 min of complete ischaemia at 37 °C. Cell yield was improved by a resuscitating perfusion from 58% to 73% and viability from 39% to 76%. 相似文献
86.
Edward Stepanski Michele Glinn Frank Zorick Timothy Roehrs Thomas Roth 《Stress and health》1994,10(4):261-266
This study assessed physiological activity in patients with chronic insomnia before sleep, during sleep and in response to acute stress. Twenty-four subjects with chronic insomnia and 25 normal sleepers slept in the laboratory overnight and were given a stressful performance task in the morning. Heart rate was significantly higher in the insomniac group at night. The next morning, heart rate was not different at baseline, but was significantly higher during the performance task in the insomniac group. These results are discussed as supporting the notion that insomniacs have greater physiological responsivity to stress. Further research is needed to determine if altered physiological activity is a cause or consequence of insomnia. 相似文献
87.
Carol Sigelman Tamara Didjurgis Brenda Marshall Frank Vargas Amanda Stewart 《Child psychiatry and human development》1992,22(4):265-276
Native American, Hispanic, and Anglo sixth graders reacting to an example of teenage problem drinking expressed similar beliefs and attitudes in many respects. However, Native American children viewed the problem as less serious, subscribed more to a disease theory of alcoholism, attributed less causal responsibility to the individual, and adopted a less aggressive approach toward treatment than did Hispanic, and especially Anglo, children. Their less conventional value orientations accounted for all these differences except their stronger endorsement of a disease theory of problem drinking. 相似文献
88.
89.
90.
To better understand adjustment following spinal cord injury (SCI), 106 subjects from two samples (N = 53 each) were administered the SCL-90-R, a symptom checklist, and the Multidimensional Health Locus of Control scales. Sample 1 subjects were admitted for rehabilitation during 1981 to 1982 and sample 2 subjects were admitted during 1984 to 1986. Sample 2 subjects entered rehabilitation programs more quickly after injury and reported more anxiety, phobic anxiety, and hostility than sample 1 subjects. Within each sample, there was no evidence for a relationship between age or time since injury and health beliefs or psychological distress. This study does not support stage theory for adjustment after catastrophic injury, but does suggest the importance of understanding the impact of social policy changes in adjustment following spinal cord injury. 相似文献