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排序方式: 共有1048条查询结果,搜索用时 15 毫秒
71.
72.
A Shnaider A Basok B V Rogachev M Zlotnik A Tomer 《American journal of nephrology》2001,21(6):494-497
BACKGROUND/AIM: Few cases are found in the literature regarding autoimmune hemolytic anemia which is Coombs' test positive in kidney transplant patients, although hemolytic uremic syndrome due to cyclosporin and FK506 has been well described. In the following, we describe a case of severe life-threatening Coombs' test negative autoimmune hemolytic anemia after kidney transplantation. METHODS: Soon after undergoing renal transplantation, the patient presented with hemolytic anemia. Kidney biopsy, routine Coombs' test, gel filtration and flow-cytometric assay were undertaken. RESULTS: Kidney biopsy ruled out hemolytic uremic syndrome; although Coombs' test and gel filtration assay were negative, flow cytometry revealed circulating antierythrocytic autoantibodies. CONCLUSIONS: Our findings indicate that flow cytometry may be an efficient method in the diagnosis of hemolysis of unknown origin in transplant patients. We further hypothesize that the underlying mechanism of autoimmune hemolytic anemia is related to the passenger B lymphocytes in the graft. 相似文献
73.
74.
Andrey A. Toropov Alla P. Toropova Emilio Benfenati 《Chemical biology & drug design》2009,73(4):482-482
75.
Baumann M Bonnetain F Briançon S Alla F 《Journal of clinical pharmacy and therapeutics》2004,29(5):405-415
AIM: To assess the relationships between socio-demographic factors, quality of life and attitudes towards psychotropic drugs and dependency and to compare those relationships in continuous consumers (CC), occasional consumers (OC) and non-consumers (NC) of those drugs. METHODS: Quality of life (SF36) and attitudes (14 statements) were measured in 601 subjects (45-60 years old) from the SUVIMAX cohort (SUpplementation en VItamines et en sels Mineraux AntioXydants). Data were obtained on 334 NC, 142 CC, 125 OC from the inclusion questionnaire and the monthly consumption report notebooks kept by subjects between 1994 and 1998. Dichotomous and polychotomous logistic regressions were used for the analysis. RESULTS: The lower the quality of life score the more frequent was consumption. NC tended to be men, with high quality of life scores. They entertained negative attitudes towards psychotropics and dependency. OC tended to be women reporting a chronic pathology, with fairly high social status. They had intermediate quality of life and denied dependency. CC tended to be men with no professional activity and low quality of life scores in particular for mental health and perceived health. They had positive attitudes towards psychotropics and accept dependency. DISCUSSION: Assessment of patients' quality of life and understanding of their attitudes towards psychotropics can provide essential information for those in charge of health promotion programmes and may help in identifying new intervention strategies. Preventive education and follow-up of therapy may be better suited to the needs of patients. 相似文献
76.
Desirée Schubert Marie-Christine Klein Sarah Hassdenteufel Andrés Caballero-Oteyza Linlin Yang Michele Proietti Alla Bulashevska Janine Kemming Johannes Kühn Sandra Winzer Stephan Rusch Manfred Fliegauf Alejandro A. Schäffer Stefan Pfeffer Roger Geiger Adolfo Cavalié Hongzhi Cao Fang Yang Bodo Grimbacher 《The Journal of allergy and clinical immunology》2018,141(4):1427-1438
77.
Susanne Unger Maximilian Seidl Pauline van Schouwenburg Mirzokhid Rakhmanov Alla Bulashevska Natalie Frede Bodo Grimbacher Jens Pfeiffer Klaudia Schrenk Luis Munoz Leif Hanitsch Ina Stumpf Fabian Kaiser Oliver Hausmann Florian Kollert Sigune Goldacker Mirjam van der Burg Baerbel Keller Klaus Warnatz 《The Journal of allergy and clinical immunology》2018,141(2):730-740
78.
Samira Rostom Karima Benbouaaza Bouchra Amine Rachid Bahiri Yousra Ibn Yacoub Sanae Ali Ou Alla Redouane Abouqal Najia Hajjaj-Hassouni 《Clinical rheumatology》2010,29(7):781-788
The objectives of this study are to translate, adapt in the Moroccan cultural context, and validate in patients with ankylosing
spondylitis (AS) the Bath Ankylosing Spondylitis Functional Index (BASFI) and Bath Ankylosing Spondylitis Disease Activity
Index (BASDAI). The cross-cultural adaptation of the BASFI and BASDAI was obtained in accordance with the guidelines for translation
of the health status measures. Eighty-five patients with AS were included in the study. The test–retest reliability and the
internal consistency were analyzed, and both questionnaires were assessed for external construct validity. Structural validity
was analyzed with correlation matrix. Twenty-four-hour test–retest reliability was good: BASFI intraclass correlation coefficient
(ICC) = 0.96 (confidence interval (CI) at 95%, 0.93–0.97), BASDAI ICC = 0.93 (CI at 95%, 0.90–0.95). Cronbach’s alpha was
0.90 for the BASFI and 0.86 for BASDAI. The construct validity of the instruments was evaluated. The BASFI showed a strong
validity when correlating its results with Schober’s test (r = −0.56), occipital wall distance (r = 0.46), chest expansion (r = −0.46), BASDAI (r = 0.54), Bath Ankylosing Spondylitis Metrology Index (r = 0.70), Bath Ankylosing Spondylitis Global Score (BAS-G; r = 0.58), Bath Ankylosing Spondylitis Radiology Index (r = 0.61), and the radiological changes in sacroiliac joints (r = 0.54). A good correlation was observed between the BASDAI and the spinal pain (r = 0.53), the number of nocturnal awakenings (r = 0.57), the morning stiffness (r = 0.65), the enthesic index (r = 0.47), the BAS-G (r = 0.53), the BASFI (r = 0.54), and the erythrocyte sedimentation rate (r = 0.41; for all p < 0.001). The correlation matrix showed an intermediate correlation between items. The Moroccan version of the BASFI and
the BASDAI showed adequate reliability and validity. These instruments can be used in the clinical evaluation of Moroccan
and Arabic-speaking patients with AS. 相似文献
79.
Sonja von Campenhausen Yaroslav WinterAntonio Rodrigues e Silva Christina SampaioEvzen Ruzicka Paolo BaroneWerner Poewe Alla GuekhtCéu Mateus Karl-P. PfeifferKarin Berger Jana SkoupaKai Bötzel Sabine Geiger-GritschUwe Siebert Monika Balzer-GeldsetzerWolfgang H. Oertel Richard Dodel Jens P. Reese 《European neuropsychopharmacology》2011,21(2):180-191
We investigated the costs of Parkinson's Disease (PD) in 486 patients based on a survey conducted in six countries. Economic data were collected over a 6-month period and presented from the societal perspective. The total mean costs per patient ranged from EUR 2620 to EUR 9820. Direct costs totalled about 60% to 70% and indirect costs about 30% to 40% of total costs. The proportions of costs components of PD vary notably; variations were due to differences in country-specific health system characteristics, macro economic conditions, as well as frequencies of resource use and price differences. However, inpatient care, long-term care and medication were identified as the major expenditures in the investigated countries. 相似文献